Medically reviewed by Drugs.com. Last updated on Mar 20, 2023.
Applies to the following strengths: 5 mg; 10 mg; 15 mg; 20 mg
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Insomnia
10 mg orally once a day at bedtime
Maximum dose: 20 mg once a day
- Take within 30 minutes of going to bed, with at least 7 hours remaining before the planned time of awakening.
- If 10 mg is well-tolerated but not effective, the dose can be increased.
- Time to effect may be delayed if taken with or soon after a meal.
Use: Insomnia characterized by difficulties with sleep onset and/or sleep maintenance.
Renal Dose Adjustments
No adjustment recommended
Liver Dose Adjustments
Mild to moderate liver dysfunction (Child-Pugh up to 9): No adjustment recommended
Severe liver dysfunction: Not recommended
This drug should be used at the lowest effective dose in order to achieve therapeutic efficacy and minimize adverse effects.
- Exposure is increased in women and in obese patients. Particularly in obese women, the increased risk of adverse effects should be considered before increasing the dose.
- When combined with other CNS depressant drugs, dosage adjustment of suvorexant and/or the other drug(s) may be necessary.
CYP450 3A4 inhibitors:
- If combined with a moderate inhibitor: 5 mg a day; generally not to exceed 10 mg a day
- If combined with a strong inhibitor: Not recommended
Safety and efficacy have not been established in patients younger than 18 years.
Consult WARNINGS section for additional precautions.
US Controlled Substance: Schedule IV
Data not available
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- Drug class: miscellaneous anxiolytics, sedatives and hypnotics
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