Loratadine / Pseudoephedrine Dosage

Medically reviewed on October 9, 2018.

Usual Adult Dose for Allergic Rhinitis

1 tablet (5 mg-120 mg) orally twice a day
-or-
1 tablet (10 mg-240 mg) orally once daily.

Usual Adult Dose for Nasal Congestion

1 tablet (5 mg-120 mg) orally twice a day
-or-
1 tablet (10 mg-240 mg) orally once daily.

Usual Pediatric Dose for Allergic Rhinitis

over 12 years:

1 tablet (5 mg-120 mg) orally twice a day
-or-
1 tablet (10 mg-240 mg) orally once daily.

Usual Pediatric Dose for Nasal Congestion

over 12 years:

1 tablet (5 mg-120 mg) orally twice a day
-or-
1 tablet (10 mg-240 mg) orally once daily.

Renal Dose Adjustments

1 tablet (5 mg-120 mg) orally once daily
-or-
1 tablet (10 mg-240 mg) orally every other day.

Liver Dose Adjustments

The manufacturer recommends that tablets containing loratadine in fixed combination with pseudoephedrine sulfate generally not be used in patients with hepatic impairment.

Dose Adjustments

Pseudoephedrine is eliminated by the kidney and may accumulate in patients with renal dysfunction. Patients with renal dysfunction should be monitored for signs and symptoms of toxicity when using pseudoephedrine.

Precautions

The FDA has not approved use of over-the-counter cough and cold medications to children aged less than 2 years, and proper dosing for children in this age group has not been studied. Clinicians should be aware of the risk for serious illness or fatal overdose from administration of cough and cold medications to children aged less than 2 years. Clinicians should be certain that caregivers understand 1) the importance of administering cough and cold medications only as directed and 2) the risk for overdose if they administer additional medications that might contain the same ingredient.

Dialysis

Pseudoephedrine is partially removed by hemodialysis, therefore doses should be given following dialysis sessions.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer