Gold Sodium Thiomalate Dosage

Usual Adult Dose for Rheumatoid Arthritis

Initial dose: 10 mg IM one time as a test dose.
Observe for 15-30 minutes for adverse/allergic reaction.
25 mg IM one week later and repeat in another week. Then 50 mg IM once a week until a cumulative dose of 1000 mg has been reached.
Maintenance dose: 25 to 50 mg every other week for 2 to 20 weeks. If the clinical course remains stable, give 25 to 50 mg every third and subsequently every fourth week indefinitely.

Renal Dose Adjustments

Gold sodium thiomalate is contraindicated in patients with renal dysfunction.

Precautions

Gold sodium thiomalate is contraindicated in patients with renal dysfunction. Prior to initiation of therapy, a CBC with differential, platelet count, urinalysis, renal and liver function tests should be performed. Thereafter, a CBC with differential, platelet count, and urinalysis should be done prior to each injection.

Other Comments

If no response is noted after 1000-1200 mg, alternative therapy should be considered.

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer