Skip to Content

Formoterol / Glycopyrrolate Dosage

Applies to the following strength(s): 4.8 mcg-9 mcg/inh

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Chronic Obstructive Pulmonary Disease - Maintenance

2 inhalations orally twice a day, in the morning and in the evening
Maximum dose: 2 inhalations twice daily

Comments:
-Two inhalations of formoterol 4.8 mcg-glycopyrrolate 9 mcg equal one dose.

Uses: Long-term, maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema

Renal Dose Adjustments

No adjustment recommended.

Liver Dose Adjustments

No adjustment recommended.

Precautions

US BOXED WARNING(S):
Asthma -Related Death:
Long-acting beta2-adrenergic agonists (LABAs) increase the risk of asthma-related death. Data from a large placebo-controlled US trial that compared the safety of another LABA (salmeterol) with placebo added to usual asthma therapy showed an increase in asthma-related deaths in subjects receiving salmeterol. This finding with salmeterol is considered a class effect of all LABAs, including formoterol fumarate, one of the active ingredients in this combination drug.
The safety and efficacy of this combination drug in patients with asthma have not been established and it is not indicated for the treatment of asthma.

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-For oral inhalation only.
-Priming the inhalation device before using for the first time to ensure appropriate drug content in each actuation. The manufacturer product information should be consulted for additional instructions for its use.
-Shake well before using.

Missed dose:
-If a dose is missed, take the next dose at the usual time.
-Do not use more often or more puffs than prescribed.

Storage requirements:
-Store at controlled room temperature 20C to 25C (68F to 77F)
-The canister should be at room temperature before use

Limitations of use:
-This drug is not indicated for the relief of acute bronchospasm or for the treatment of asthma.

Patient advice:
-Patients should read the medication guide and instructions for the use of this drug.
-A rescue inhaler should be provided to patients to treat acute symptoms. Patients should be instructed on how to use the rescue inhaler.
-Seek medical attention immediately if symptoms get worse, or if more inhalations than usual of their rescue inhaler are needed.
-Therapy should not be stopped without physician/provider guidance since symptoms may recur after discontinuation.
-Discontinue previous regular use of short acting beta2-agonist and use them only for the symptomatic relief of acute symptoms.

Hide