Enoxacin Dosage

Usual Adult Dose for Gonococcal Infection - Uncomplicated

400 mg orally one time.

Usual Adult Dose for Urinary Tract Infection

Uncomplicated: 200 mg orally every 12 hours for 7 days.
Complicated: 400 mg orally every 12 hours for 14 days.

Usual Adult Dose for Prostatitis

400 mg orally every 12 hours for 14 to 30 days.

Usual Adult Dose for Pyelonephritis

400 mg orally every 12 hours for 14 days.

Usual Adult Dose for Epididymitis - Non-Specific

200 mg orally every 12 hours for 14 days.

Renal Dose Adjustments

CrCl<30 mL/min/1.73 m2: After a normal initial dose, one-half the recommended dose orally every 12 hours.

Dialysis

Enoxacin is poorly removed (<5%) by hemodialysis.

Other Comments

Enoxacin should be taken at least one hour before or at least two hours after a meal.

In patients being treated with enoxacin for gonococcal infections, doxycycline therapy is also recommended to treat potential coexisting chlamydial infections, unless the patient is pregnant.

Patients should be instructed to refer sex partner(s) for evaluation and treatment.