Diphenhydramine / Phenylephrine Dosage
Applies to the following strength(s): 6.25 mg-2.5 mg/5 mL ; 6.25 mg-6.25 mg/5 mL ; 12.5 mg-5 mg ; 25 mg-7.5 mg/5 mL ; 25 mg-10 mg ; 12.5 mg-5 mg/5 mL
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Allergic Rhinitis
diphenhydrAMINE-phenylephrine 25 mg-10 mg oral tablet:
diphenhydrAMINE-phenylephrine 12.5 mg-5 mg oral tablet, chewable, extended release:
1 to 2 tablets orally every 12 hours
diphenhydrAMINE-phenylephrine 25 mg-7.5 mg/5 mL oral suspension, extended release:
5 to 10 mL orally every 12 hours
diphenhydrAMINE-phenylephrine 25 mg-7.5 mg/5 mL oral liquid:
5 mL orally every 4 to 6 hours, not to exceed 30 mL in 24 hours
diphenhydrAMINE-phenylephrine 6.25 mg-2.5 mg/5 mL oral liquid:
20 mL orally every 4 to 6 hours, not to exceed 120 mL in 24 hours
Usual Adult Dose for Cold Symptoms
diphenhydrAMINE-phenylephrine 25 mg-10 mg oral tablet:
diphenhydrAMINE-phenylephrine 12.5 mg-5 mg oral tablet, chewable, extended release:
1 to 2 tablets orally every 12 hours
diphenhydrAMINE-phenylephrine 25 mg-7.5 mg/5 mL oral suspension, extended release:
5 to 10 mL orally every 12 hours
diphenhydrAMINE-phenylephrine 25 mg-7.5 mg/5 mL oral liquid:
5 mL orally every 4 to 6 hours, not to exceed 30 mL in 24 hours
diphenhydrAMINE-phenylephrine 6.25 mg-2.5 mg/5 mL oral liquid:
20 mL orally every 4 to 6 hours, not to exceed 120 mL in 24 hours
Usual Adult Dose for Sinusitis
diphenhydrAMINE-phenylephrine 25 mg-10 mg oral tablet:
diphenhydrAMINE-phenylephrine 12.5 mg-5 mg oral tablet, chewable, extended release:
1 to 2 tablets orally every 12 hours
diphenhydrAMINE-phenylephrine 25 mg-7.5 mg/5 mL oral suspension, extended release:
5 to 10 mL orally every 12 hours
diphenhydrAMINE-phenylephrine 25 mg-7.5 mg/5 mL oral liquid:
5 mL orally every 4 to 6 hours, not to exceed 30 mL in 24 hours
diphenhydrAMINE-phenylephrine 6.25 mg-2.5 mg/5 mL oral liquid:
20 mL orally every 4 to 6 hours, not to exceed 120 mL in 24 hours
Usual Pediatric Dose for Allergic Rhinitis
diphenhydrAMINE-phenylephrine 25 mg-10 mg oral tablet:
diphenhydrAMINE-phenylephrine 12.5 mg-5 mg oral tablet, chewable, extended release:
13 yrs or older: 1 to 2 tablets orally every 12 hours
6 to 12 yrs: 1/2 to 1 tablet orally every 12 hours
diphenhydrAMINE-phenylephrine 25 mg-7.5 mg/5 mL oral suspension:
13 yrs or older: 5 to 10 mL orally every 12 hours
6 to 12 yrs: 2.5 to 5 mL orally every 12 hours
2 to less than 6 yrs: 1.25 to 2.5 mL orally every 12 hours
diphenhydrAMINE-phenylephrine 6.25 mg-6.25 mg/5 mL oral suspension, extended release:
6 to 11 yrs: 10 mL orally every 4 hours, not to exceed 6 doses in 24 hours.
diphenhydrAMINE-phenylephrine 25 mg-7.5 mg/5 mL oral liquid:
12 yrs or older: 5 mL orally every 4 to 6 hours, not to exceed 30 mL in 24 hours
6 to 11 yrs: 2.5 mL orally every 4 to 6 hours, not to exceed 15 mL in 24 hours
diphenhydrAMINE-phenylephrine 6.25 mg-2.5 mg/5 mL oral liquid:
12 yrs or older: 20 mL orally every 4 hours, not to exceed 120 mL in 24 hours
6 to 11 yrs: 10 mL orally every 4 hours, not to exceed 60 mL in 24 hours
diphenhydrAMINE-phenylephrine 12.5 mg-5 mg/5 mL oral liquid:
6 to 11 yrs: 5 mL orally every 4 hours, not to exceed 30 mL in 24 hours
diphenhydrAMINE-phenylephrine 12.5 mg-5 mg oral disintegrating strip:
6 to 11 yrs: dissolve 1 strip on tongue
Usual Pediatric Dose for Cold Symptoms
diphenhydrAMINE-phenylephrine 25 mg-10 mg oral tablet:
diphenhydrAMINE-phenylephrine 12.5 mg-5 mg oral tablet, chewable, extended release:
13 yrs or older: 1 to 2 tablets orally every 12 hours
6 to 12 yrs: 1/2 to 1 tablet orally every 12 hours
diphenhydrAMINE-phenylephrine 25 mg-7.5 mg/5 mL oral suspension:
13 yrs or older: 5 to 10 mL orally every 12 hours
6 to 12 yrs: 2.5 to 5 mL orally every 12 hours
2 to less than 6 yrs: 1.25 to 2.5 mL orally every 12 hours
diphenhydrAMINE-phenylephrine 6.25 mg-6.25 mg/5 mL oral suspension, extended release:
6 to 11 yrs: 10 mL orally every 4 hours, not to exceed 6 doses in 24 hours.
diphenhydrAMINE-phenylephrine 25 mg-7.5 mg/5 mL oral liquid:
12 yrs or older: 5 mL orally every 4 to 6 hours, not to exceed 30 mL in 24 hours
6 to 11 yrs: 2.5 mL orally every 4 to 6 hours, not to exceed 15 mL in 24 hours
diphenhydrAMINE-phenylephrine 6.25 mg-2.5 mg/5 mL oral liquid:
12 yrs or older: 20 mL orally every 4 hours, not to exceed 120 mL in 24 hours
6 to 11 yrs: 10 mL orally every 4 hours, not to exceed 60 mL in 24 hours
diphenhydrAMINE-phenylephrine 12.5 mg-5 mg/5 mL oral liquid:
6 to 11 yrs: 5 mL orally every 4 hours, not to exceed 30 mL in 24 hours
diphenhydrAMINE-phenylephrine 12.5 mg-5 mg oral disintegrating strip:
6 to 11 yrs: dissolve 1 strip on tongue
Usual Pediatric Dose for Sinusitis
diphenhydrAMINE-phenylephrine 25 mg-10 mg oral tablet:
diphenhydrAMINE-phenylephrine 12.5 mg-5 mg oral tablet, chewable, extended release:
13 yrs or older: 1 to 2 tablets orally every 12 hours
6 to 12 yrs: 1/2 to 1 tablet orally every 12 hours
diphenhydrAMINE-phenylephrine 25 mg-7.5 mg/5 mL oral suspension:
13 yrs or older: 5 to 10 mL orally every 12 hours
6 to 12 yrs: 2.5 to 5 mL orally every 12 hours
2 to less than 6 yrs: 1.25 to 2.5 mL orally every 12 hours
diphenhydrAMINE-phenylephrine 6.25 mg-6.25 mg/5 mL oral suspension, extended release:
6 to 11 yrs: 10 mL orally every 4 hours, not to exceed 6 doses in 24 hours.
diphenhydrAMINE-phenylephrine 25 mg-7.5 mg/5 mL oral liquid:
12 yrs or older: 5 mL orally every 4 to 6 hours, not to exceed 30 mL in 24 hours
6 to 11 yrs: 2.5 mL orally every 4 to 6 hours, not to exceed 15 mL in 24 hours
diphenhydrAMINE-phenylephrine 6.25 mg-2.5 mg/5 mL oral liquid:
12 yrs or older: 20 mL orally every 4 hours, not to exceed 120 mL in 24 hours
6 to 11 yrs: 10 mL orally every 4 hours, not to exceed 60 mL in 24 hours
diphenhydrAMINE-phenylephrine 12.5 mg-5 mg/5 mL oral liquid:
6 to 11 yrs: 5 mL orally every 4 hours, not to exceed 30 mL in 24 hours
diphenhydrAMINE-phenylephrine 12.5 mg-5 mg oral disintegrating strip:
6 to 11 yrs: dissolve 1 strip on tongue
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Dialysis
Data not available
More about diphenhydramine/phenylephrine
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- Dosage Information
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- En Español
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- Drug class: upper respiratory combinations
Consumer resources
- Diphenhydramine/phenylephrine
- Diphenhydramine/phenylephrine chewable tablets
- Diphenhydramine/phenylephrine liquid
- Diphenhydramine/phenylephrine strips
- Diphenhydramine/phenylephrine suspension
- Diphenhydramine and phenylephrine
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