Diphenhydramine / Naproxen Dosage

Medically reviewed by Drugs.com. Last updated on Dec 8, 2023.

Usual Adult Dose for Insomnia

Initial dose: 2 caplets at bedtime
Maximum dose: 2 caplets in 24 hours

Use: To relief occasional sleeplessness associated with minor aches

Usual Adult Dose for Pain

Initial dose: 2 caplets at bedtime
Maximum dose: 2 caplets in 24 hours

Use: To relief occasional sleeplessness associated with minor aches

Usual Pediatric Dose for Insomnia

For children over 12 years old.
Initial dose: 2 caplets at bedtime
Maximum dose: 2 caplets in 24 hours

Usual Pediatric Dose for Pain

For children over 12 years old.
Initial dose: 2 caplets at bedtime
Maximum dose: 2 caplets in 24 hours

Renal Dose Adjustments

Data not available.

Liver Dose Adjustments

Data not available.

Precautions

US FDA requires a medication guide to assure safe use. For additional information: www.fda.gov/drugs/drug-safety-and-availability/medication-guides

Safety and efficacy have not been established in patients younger than 12 years; this drug is not recommended for use in these patients.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available.

Other Comments

Administration advice:

• Do not take more than directed.
• Take with a full glass of water.
• This drug may take longer to work if administered with food.

Storage requirements:

• Keep outer carton.
• Store at 20 to 25C (68 to 77F), avoiding high humidity and excessive heat (above 40C or 104F).

Patient advice:

• Talk to your doctor before using if you have allergies to other pain medications.
• Do not take unless you have time for a full night sleep.
• Talk to your doctor before using if you have a history of heartburn, stomach bleeding, high blood pressure, heart disease, liver or kidney disease, asthma, emphysema, chronic bronchitis, glaucoma or trouble urinating.
• Do not take if you are already taking other sedatives or tranquilizers or any other antihistamines.
• This drug will make you drowsy. Avoid driving and other activities that require your full attention.
• Stop using immediately and contact your doctor if you feel faint, vomit blood, have bloody or black stools, have stomach pain that does not improve, or difficulty swallowing.
• Talk to your doctor if your sleeplessness persists after 2 weeks.
• In case of overdosage get medical help or contact a Poison Control Center immediately.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer