Diphenhydramine/naproxen Interactions
There are 798 drugs known to interact with diphenhydramine/naproxen, along with 19 disease interactions, and 4 alcohol/food interactions. Of the total drug interactions, 114 are major, 663 are moderate, and 21 are minor.
- View all 798 medications that may interact with diphenhydramine/naproxen
- View diphenhydramine/naproxen alcohol/food interactions (4)
- View diphenhydramine/naproxen disease interactions (19)
Most frequently checked interactions
View interaction reports for diphenhydramine / naproxen and the medicines listed below.
- Advair HFA (fluticasone / salmeterol)
- Aleve-D Sinus & Cold (naproxen / pseudoephedrine)
- Aricept (donepezil)
- Aspir 81 (aspirin)
- Augmentin (amoxicillin / clavulanate)
- Belbuca (buprenorphine)
- Benadryl (diphenhydramine)
- Benylin DM (dextromethorphan)
- Buckley's Complete (acetaminophen)
- Celebrex (celecoxib)
- Cialis (tadalafil)
- Ginger Root (ginger)
- Imitrex (sumatriptan)
- Imodium (loperamide)
- Keflex (cephalexin)
- Keppra (levetiracetam)
- Lamictal (lamotrigine)
- Lasix (furosemide)
- Lexapro (escitalopram)
- Lidocaine Viscous (lidocaine topical)
- Lipitor (atorvastatin)
- Lyrica (pregabalin)
- Milk of Magnesia (magnesium hydroxide)
- Monistat 7 (miconazole topical)
- Monistat Soothing Care Itch Relief Cream (hydrocortisone topical)
- Mucus Relief D (guaifenesin / pseudoephedrine)
- Naproxen Sodium DS (naproxen)
- Nuvigil (armodafinil)
- Pepto-Bismol InstaCool (bismuth subsalicylate)
- Probiotic Formula (bifidobacterium infantis / lactobacillus acidophilus)
Diphenhydramine/naproxen alcohol/food interactions
There are 4 alcohol/food interactions with diphenhydramine / naproxen.
Diphenhydramine/naproxen disease interactions
There are 19 disease interactions with diphenhydramine / naproxen which include:
- depression
- asthma
- fluid retention
- GI toxicity
- rash
- renal toxicities
- thrombosis
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- sodium
- anemia
- hepatotoxicity
- hyperkalemia
- platelet aggregation inhibition
Report options
More about diphenhydramine / naproxen
- diphenhydramine/naproxen consumer information
- Compare alternatives
- Reviews (43)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: analgesic combinations
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
