Cortisone Dosage

Usual Adult Dose for Adrenal Insufficiency

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Idiopathic (Immune) Thrombocytopenic Purpura

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Shock

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Hemolytic Anemia

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Erythroblastopenia

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Loeffler's Syndrome

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Sarcoidosis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Berylliosis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Lymphoma

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Nephrotic Syndrome

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Uveitis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Iritis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Keratitis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Conjunctivitis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Iridocyclitis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Chorioretinitis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Choroiditis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Systemic Lupus Erythematosus

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Dermatomyositis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Ankylosing Spondylitis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Bursitis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Osteoarthritis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Rheumatoid Arthritis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Gouty Arthritis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Psoriatic Arthritis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Epicondylitis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Pediatric Dose for Adrenal Insufficiency

0.5 mg to 0.75 mg/kg/day orally given in equally divided doses every 8 hours. Alternatively, 0.25 mg to 0.35 mg/kg IM once daily

Renal Dose Adjustments

Steroids should be used with caution in patients with renal insufficiency.

Liver Dose Adjustments

Steroids should be used with caution in patients with cirrhosis.

Dose Adjustments

Dosages smaller than 25 mg per day may be enough in less severe diseases. In severe diseases dosages higher than 300 mg per day may be required.

Maintain patient on lowest dosage that provides an adequate clinical response, by decreasing the initial dosage gradually in small amounts.

Titrate patient off therapy gradually if drug has been used for a few days.

Precautions

Secondary adrenocortical insufficiency may result from rapid withdrawal of cortisone and may be minimized with gradual tapering of dosage.

Dialysis

Supplemental dose is not necessary.

Other Comments

The injectable suspension is intended for intramuscular administration only.