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Cortisone Pregnancy and Breastfeeding Warnings

Cortisone is also known as: Cortone Acetate

Medically reviewed on June 7, 2018

Cortisone Pregnancy Warnings

Cortisone has not been formally assigned to pregnancy category by the FDA. Cortisone has been assigned to pregnancy Risk Factor C (Risk Factor D if used in the 1st trimester) by Briggs et al. Animal studies involving cortisol administration have revealed evidence of an increased incidence of cleft palate in offspring, stillborn fetuses, and decreased fetal size. There are no controlled data in human pregnancy. Cortisone is only recommended for use during pregnancy when there are no alternatives and benefit outweighs risk.

See references

Cortisone Breastfeeding Warnings

There are no data on the excretion of cortisone into human milk. Some corticosteroids are excreted into human milk in small amounts. The manufacturer recommends that due to the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

See references

References for pregnancy information

  1. Dancis J, Jansen V, Levitz M, Rosner W "Effect of protein binding on transfer and metabolism of cortisol in perfused human placenta." J Clin Endocrinol Metab 46 (1978): 863-8
  2. "Product Information. Cortone Acetate (cortisone)." Merck & Co, Inc, West Point, PA.
  3. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 7th ed." Philadelphia, PA: Lippincott Williams & Wilkins (2005):

References for breastfeeding information

  1. "Product Information. Cortone Acetate (cortisone)." Merck & Co, Inc, West Point, PA.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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