Skip to Content
Diagnosed with AS? Biologics can help >

Cortisone Pregnancy and Breastfeeding Warnings

Cortisone is also known as: Cortone Acetate

Cortisone Pregnancy Warnings

Cortisone has not been formally assigned to pregnancy category by the FDA. Cortisone has been assigned to pregnancy Risk Factor C (Risk Factor D if used in the 1st trimester) by Briggs et al. Animal studies involving cortisol administration have revealed evidence of an increased incidence of cleft palate in offspring, stillborn fetuses, and decreased fetal size. There are no controlled data in human pregnancy. Cortisone is only recommended for use during pregnancy when there are no alternatives and benefit outweighs risk.

See references

Cortisone Breastfeeding Warnings

There are no data on the excretion of cortisone into human milk. Some corticosteroids are excreted into human milk in small amounts. The manufacturer recommends that due to the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

See references

References for pregnancy information

  1. Dancis J, Jansen V, Levitz M, Rosner W "Effect of protein binding on transfer and metabolism of cortisol in perfused human placenta." J Clin Endocrinol Metab 46 (1978): 863-8
  2. "Product Information. Cortone Acetate (cortisone)." Merck & Co, Inc, West Point, PA.
  3. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 7th ed." Philadelphia, PA: Lippincott Williams & Wilkins (2005):

References for breastfeeding information

  1. "Product Information. Cortone Acetate (cortisone)." Merck & Co, Inc, West Point, PA.

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.