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Chlorpheniramine / Pseudoephedrine Dosage

Medically reviewed by Drugs.com. Last updated on Aug 1, 2023.

Applies to the following strengths: 1 mg-15 mg/5 mL; 3 mg-45 mg/5 mL; 2 mg-30 mg/5 mL; 4 mg-60 mg; 1 mg-15 mg; 8 mg-120 mg; 10 mg-65 mg; 12 mg-120 mg; 2 mg-30 mg; 4.5 mg-75 mg/5 mL; 12 mg-100 mg; 5 mg-75 mg/5 mL; 0.8 mg-9 mg/mL; 2 mg-15 mg; 6 mg-30 mg/5 mL; 4 mg-30 mg; tannate 4 mg-30 mg

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Allergic Rhinitis

Chlorpheniramine-pseudoephedrine 2 mg-15 mg oral tablet, chewable:
2 tablets orally every 4 to 6 hours.

Chlorpheniramine-pseudoephedrine 2 mg-30 mg oral tablet, chewable:
2 tablets orally every 4 to 6 hours not to exceed 4 doses per day.

Chlorpheniramine-pseudoephedrine 4 mg-30 mg oral tablet, chewable, extended release:
1 to 2 tablets orally every 12 hours.

Chlorpheniramine-pseudoephedrine 5 mg-75 mg/5 mL oral suspension, extended release:
10 to 20 mL orally every 12 hours not to exceed 40 mL daily.

Chlorpheniramine-pseudoephedrine tannate 4 mg-30 mg oral tablet, chewable, extended release:
1 to 2 tablets orally every 12 hours.

Usual Adult Dose for Sinusitis

Chlorpheniramine-pseudoephedrine 2 mg-15 mg oral tablet, chewable:
2 tablets orally every 4 to 6 hours.

Chlorpheniramine-pseudoephedrine 2 mg-30 mg oral tablet, chewable:
2 tablets orally every 4 to 6 hours not to exceed 4 doses per day.

Chlorpheniramine-pseudoephedrine 4 mg-30 mg oral tablet, chewable, extended release:
1 to 2 tablets orally every 12 hours.

Chlorpheniramine-pseudoephedrine 5 mg-75 mg/5 mL oral suspension, extended release:
10 to 20 mL orally every 12 hours not to exceed 40 mL daily.

Chlorpheniramine-pseudoephedrine tannate 4 mg-30 mg oral tablet, chewable, extended release:
1 to 2 tablets orally every 12 hours.

Usual Pediatric Dose for Allergic Rhinitis

Chlorpheniramine-pseudoephedrine 0.8 mg-9 mg/mL oral liquid:
6 to 12 months: 0.5 mL orally four times daily not to exceed 4 doses per day.
1 to 2 years: 0.75 mL orally four times daily not to exceed 4 doses per day.
2 to 3 years: 1 mL orally four times daily not to exceed 4 doses per day.

Chlorpheniramine-pseudoephedrine 2 mg-15 mg oral tablet, chewable:
6 to 11 years: 1 tablet orally every 4 to 6 hours.
12 years or older: 2 tablets orally every 4 to 6 hours.

Chlorpheniramine-pseudoephedrine 2 mg-30 mg oral tablet, chewable
6 to 11 years: 1 tablet orally every 4 to 6 hours not to exceed 4 doses per day.
12 years or older: 2 tablets orally every 4 to 6 hours not to exceed 4 doses per day.

Chlorpheniramine-pseudoephedrine 4 mg-30 mg oral tablet, chewable, extended release:
2 to 5 years: 1/2 tablet orally every 12 hours.
6 to 11 years: 1/2 to 1 tablet orally every 12 hours.
12 years or older: 1 to 2 tablets orally every 12 hours.

Chlorpheniramine-pseudoephedrine 5 mg-75 mg/5 mL oral suspension, extended release:
2 to 5 years: 2.5 to 5 mL orally every 12 hours not to exceed 10 mL daily.
6 to 11 years: 5 to 10 mL orally every 12 hours not to exceed 20 mL daily.
12 years or older: 10 to 20 mL orally every 12 hours not to exceed 40 mL daily.

Chlorpheniramine-pseudoephedrine tannate 4 mg-30 mg oral tablet, chewable, extended release:
2 to 5 years: 1/2 tablet orally every 12 hours.
6 to 11 years: 1/2 to 1 tablet orally every 12 hours.
12 years or older: 1 to 2 tablets orally every 12 hours.

Usual Pediatric Dose for Sinusitis

Chlorpheniramine-pseudoephedrine 0.8 mg-9 mg/mL oral liquid:
6 to 12 months: 0.5 mL orally four times daily not to exceed 4 doses per day.
1 to 2 years: 0.75 mL orally four times daily not to exceed 4 doses per day.
2 to 3 years: 1 mL orally four times daily not to exceed 4 doses per day.

Chlorpheniramine-pseudoephedrine 2 mg-15 mg oral tablet, chewable:
6 to 11 years: 1 tablet orally every 4 to 6 hours.
12 years or older: 2 tablets orally every 4 to 6 hours.

Chlorpheniramine-pseudoephedrine 2 mg-30 mg oral tablet, chewable
6 to 11 years: 1 tablet orally every 4 to 6 hours not to exceed 4 doses per day.
12 years or older: 2 tablets orally every 4 to 6 hours not to exceed 4 doses per day.

Chlorpheniramine-pseudoephedrine 4 mg-30 mg oral tablet, chewable, extended release:
2 to 5 years: 1/2 tablet orally every 12 hours.
6 to 11 years: 1/2 to 1 tablet orally every 12 hours.
12 years or older: 1 to 2 tablets orally every 12 hours.

Chlorpheniramine-pseudoephedrine 5 mg-75 mg/5 mL oral suspension, extended release:
2 to 5 years: 2.5 to 5 mL orally every 12 hours not to exceed 10 mL daily.
6 to 11 years: 5 to 10 mL orally every 12 hours not to exceed 20 mL daily.
12 years or older: 10 to 20 mL orally every 12 hours not to exceed 40 mL daily.

Chlorpheniramine-pseudoephedrine tannate 4 mg-30 mg oral tablet, chewable, extended release:
2 to 5 years: 1/2 tablet orally every 12 hours.
6 to 11 years: 1/2 to 1 tablet orally every 12 hours.
12 years or older: 1 to 2 tablets orally every 12 hours.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

The FDA has not approved use of over-the-counter cough and cold medications to children aged less than 2 years, and proper dosing for children in this age group has not been studied. Clinicians should be aware of the risk for serious illness or fatal overdose from administration of cough and cold medications to children aged less than 2 years. Clinicians should be certain that caregivers understand 1) the importance of administering cough and cold medications only as directed and 2) the risk for overdose if they administer additional medications that might contain the same ingredient.

Dialysis

Data not available

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.