Aspirin / Dipyridamole Dosage

Usual Adult Dose for Ischemic Stroke - Prophylaxis

Aspirin 25 mg-Dipyridamole 200 mg orally twice a day

Comments: If intolerable headaches occur during initial treatment, switch to aspirin 25 mg-dipyridamole 200 mg orally at bedtime and low-dose aspirin in the morning; return to usual regimen as soon as possible, usually within 1 week.

Use: To reduce the risk of stroke in patients who have had transient ischemia of the brain or complete ischemic stroke due to thrombosis.

Renal Dose Adjustments

GFR 10 mL/min or greater: Data not available
GFR less than 10 mL/min: Not recommended

Liver Dose Adjustments

Mild to moderate liver dysfunction: No adjustment recommended
Severe liver dysfunction: Not recommended

Precautions

This drug is not recommended for use in children.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-If a dose is missed, patients should continue with the next regularly scheduled dose.
-This drug is not interchangeable with the individual components.

General: The amount of aspirin in this product may not provide adequate treatment for certain cardiovascular indications.

Monitoring:
-Gastrointestinal: Signs of ulceration and bleeding

Patient advice:
-Inform patients of the bleeding risk, including intracranial and gastrointestinal bleeding.
-Inform patients about signs and symptoms of bleeding, including occult bleeding.
-Counsel patients who consume three or more alcoholic drinks every day about the bleeding risks involved with chronic, heavy alcohol use while taking aspirin.
-If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential harm to the fetus.
-Tell patients to contact their physician if they experience intolerable headaches.