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Pentothal (thiopental) Disease Interactions

There are 8 disease interactions with Pentothal (thiopental):

Major

Thiopental (Includes Pentothal) ↔ Addison disease

Severe Potential Hazard, Moderate plausibility. Applies to: Adrenal Insufficiency

Thiopental should not be used in patients with Addison disease or any adrenal gland disorder.

Major

Thiopental (Includes Pentothal) ↔ asthma

Severe Potential Hazard, Moderate plausibility. Applies to: Asthma

Thiopental should not be used in patients with asthma as it can lead to intraoperative bronchospasm which can be catastrophic.

Major

Thiopental (Includes Pentothal) ↔ liver disease

Severe Potential Hazard, Moderate plausibility. Applies to: Liver Disease

Thiopental should not be used in patients with liver dysfunction. The distribution half-life and the duration of the drug action will be prolonged.

Major

Thiopental (Includes Pentothal) ↔ myasthenia gravis

Severe Potential Hazard, Moderate plausibility. Applies to: Myasthenia Gravis

Thiopental should not be used in patients with myasthenia gravis as it can prompt myasthenic crises.

Major

Thiopental (Includes Pentothal) ↔ porphyria

Severe Potential Hazard, Moderate plausibility. Applies to: Porphyria

The use of thiopental is contraindicated in patients with porphyria.

Major

Thiopental (Includes Pentothal) ↔ renal impairment

Severe Potential Hazard, Moderate plausibility. Applies to: Renal Dysfunction

Thiopental should not be used in patients with renal impairment. If so, the dose needs to be considerably reduced.

Major

Thiopental (Includes Pentothal) ↔ severe anemia

Severe Potential Hazard, Moderate plausibility. Applies to: Anemia

Thiopental should not be used in patients with severe anemia.

Major

Thiopental (Includes Pentothal) ↔ thyroid disorder

Severe Potential Hazard, Moderate plausibility. Applies to: Thyroid Disease

Thiopental should not be used in patients with thyroid disorder as it influences thyroid metabolism.

Pentothal (thiopental) drug interactions

There are 601 drug interactions with Pentothal (thiopental)

Pentothal (thiopental) alcohol/food interactions

There is 1 alcohol/food interaction with Pentothal (thiopental)

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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