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Sipuleucel-T Disease Interactions

There are 2 disease interactions with sipuleucel-T:


Sipuleucel-T (Includes Sipuleucel-T) ↔ Thromboembolism

Moderate Potential Hazard, Moderate plausibility

Applies to: Thrombotic/Thromboembolic Disorder

The use of sipuleucel-T can cause thromboembolism, including deep venous thrombosis and pulmonary embolism. It is recommended to exercise caution when using this agent in patients with risk factors for thromboembolic events. Close monitoring is recommended.


  1. "Product Information. Adagen (pegademase bovine)." Enzon Inc, Piscataway, NJ.

Sipuleucel-T (Includes Sipuleucel-T) ↔ Vascular Disorder

Moderate Potential Hazard, Moderate plausibility

Applies to: Myocardial Infarction, Cerebral Vascular Disorder

Vascular disorders that include, cerebrovascular and cardiovascular events have occurred with the use of sipuleucel-T. It is recommended to exercise caution when using this agent in patients with risk factors for vascular disorders such as, hemorrhagic and ischemic strokes, and myocardial infarctions. Close monitoring is recommended.

sipuleucel-T drug Interactions

There are 199 drug interactions with sipuleucel-T

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

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