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Revefenacin Disease Interactions

There are 4 disease interactions with revefenacin:

Moderate

Revefenacin (applies to revefenacin) glaucoma

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Glaucoma (Narrow Angle)

Revefenacin should be used with caution in patients with narrow-angle glaucoma. Prescribers and patients should be alert for signs and symptoms of acute narrow-angle glaucoma (e.g. eye pain or discomfort, blurred vision, visual halos or colored images in association with red eyes from conjunctival congestion and corneal edema). Instruct patients to consult a physician immediately if any of these signs or symptoms develops.

Moderate

Revefenacin (applies to revefenacin) hepatic impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

The systemic exposure of revefenacin is unchanged while that of its active metabolite is increased in subjects with moderate hepatic impairment. The safety of revefenacin has not been evaluated in COPD patients with mild-to-severe hepatic impairment, therefore revefenacin is not recommended in patients with any degree of hepatic impairment.

Moderate

Revefenacin (applies to revefenacin) severe renal impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction

No dosage adjustment is required in patients with renal impairment, however, patients with severe renal impairment should be monitored for systemic antimuscarinic side effects.

Moderate

Revefenacin (applies to revefenacin) urinary retention

Moderate Potential Hazard, Moderate plausibility.

Revefenacin should be used with caution in patients with urinary retention. Health care providers and patients should be alert for signs and symptoms of urinary retention (e.g. difficulty passing urine, painful urination), especially in patients with prostatic hyperplasia or bladder neck obstruction. Instruct patients to consult a healthcare provider immediately if any of these signs or symptoms develops.

Revefenacin drug interactions

There are 138 drug interactions with revefenacin

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.