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Pamabrom Disease Interactions

There is 1 disease interaction with pamabrom.


Pamabrom (applies to pamabrom) hypokalemia

Moderate Potential Hazard, Moderate plausibility.

The use of pamabrom (a theobromine derivative) has been associated with the renal elimination of potassium due to its diuretic effects. Therapy with pamabrom should be administered cautiously in patients with hypokalemia.


  1. Niemeyer C, Hasenfub G, Wais U, et al. (1983) "Pharmacokinetics of hydrochlorothiazide in relation to renal function." Eur J Clin Pharmacol, 24, p. 661-5
  2. (2002) "Product Information. Lozol (indapamide)." Rhone Poulenc Rorer
  3. (2001) "Product Information. Thalitone (chlorthalidone)." Monarch Pharmaceuticals Inc
  4. "Product Information. Minizide (polythiazide-prazosin)." Pfizer U.S. Pharmaceuticals
  5. (2001) "Product Information. Enduron (methyclothiazide)." Abbott Pharmaceutical
  6. (2001) "Product Information. Diucardin (hydroflumethiazide)." Wyeth-Ayerst Laboratories
  7. (2001) "Product Information. Exna (benzthiazide)." Wyeth-Ayerst Laboratories
View all 7 references

Pamabrom drug interactions

There are 20 drug interactions with pamabrom.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.