Orphenadrine Disease Interactions
There is 1 disease interaction with orphenadrine:
Orphenadrine (Includes Orphenadrine) ↔ Anticholinergic Effects
Severe Potential Hazard, Moderate plausibility
Applies to: Gastrointestinal Obstruction, Glaucoma/Intraocular Hypertension, Myasthenia Gravis, Urinary Retention, Esophageal Obstruction
Orphenadrine has mild anticholinergic activity, to which elderly patients are particularly sensitive. The manufacturer considers the use of orphenadrine to be contraindicated in patients with glaucoma, pyloric or duodenal obstruction, achalasia, prostatic hypertrophy, bladder neck obstruction, or myasthenia gravis. Orphenadrine should be used cautiously in other conditions that are likely to be exacerbated by anticholinergic activity, such as urinary retention and gastrointestinal obstructive disorders.
- "Product Information. Norflex (orphenadrine)." 3M Pharmaceuticals, St. Paul, MN.
orphenadrine drug Interactions
There are 801 drug interactions with orphenadrine
orphenadrine alcohol/food Interactions
There is 1 alcohol/food interaction with orphenadrine
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
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