Mulpleta Disease Interactions
There are 2 disease interactions with Mulpleta (lusutrombopag).
Lusutrombopag (applies to Mulpleta) severe renal impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
Pharmacokinetics information in patients with severe renal impairment (CrCl less than 30 mL/min) is limited. Caution is advised if using in this patient population.
References (1)
- (2018) "Product Information. Mulpleta (lusutrombopag)." Shionogi USA Inc
TPO receptor agonists (applies to Mulpleta) thrombotic / thromboembolic complications
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Thrombotic/Thromboembolic Disorder, History - Thrombotic/Thromboembolic Disorder, Protein C Deficiency
Thromboembolic complications may result from increases in platelet counts with TPO receptor agonists such as avatrombopag, lusutrombopag, and eltrombopag. Consider the potential for increased risk of thromboembolism when administering these medications to patients with known risk factors for thromboembolism, including genetic prothrombotic conditions (Factor V Leiden, Prothrombin 20210 A, Antithrombin deficiency or Protein C or S deficiency).
References (3)
- (2008) "Product Information. Promacta (eltrombopag)." GlaxoSmithKline
- (2018) "Product Information. Doptelet (avatrombopag)." Dova Pharmaceuticals
- (2018) "Product Information. Mulpleta (lusutrombopag)." Shionogi USA Inc
Switch to consumer interaction data
Mulpleta drug interactions
There are 156 drug interactions with Mulpleta (lusutrombopag).
Report options
More about Mulpleta (lusutrombopag)
- Mulpleta consumer information
- Check interactions
- Compare alternatives
- Pricing & coupons
- Drug images
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: platelet-stimulating agents
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Decadron
Decadron is used for addison's disease, adrenal insufficiency, adrenocortical insufficiency ...
Dexamethasone Intensol
Dexamethasone Intensol is used for addison's disease, adrenal insufficiency, adrenocortical ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Deltasone
Deltasone is used for acute lymphocytic leukemia, adrenocortical insufficiency, allergic reactions ...
Rituxan
Rituxan infusion is used to treat certain leukemias and lymphomas and some non-cancer conditions ...
Promacta
Promacta is used to prevent bleeding episodes in patients with chronic immune (idiopathic) ...
Rayos
Rayos (prednisone, delayed-release) is used to treat rheumatoid arthritis, polymyalgia rheumatica ...
Nplate
Nplate is used to prevent bleeding episodes in people with chronic immune thrombocytopenic purpura ...
Eltrombopag
Eltrombopag is used for aplastic anemia, immune thrombocytopenia, thrombocytopenia ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
