Linagliptin Disease Interactions
There is 1 disease interaction with linagliptin.
DPP-4 inhibitors (applies to linagliptin) pancreatitis
Moderate Potential Hazard, Low plausibility.
There have been postmarketing reports of acute pancreatitis in patients taking DPP-4 inhibitors. These drugs should be used with caution in patients with a history of pancreatitis or pancreatic disease, although it is unknown if they are at increased risk. Patients should be observed for signs and symptoms of pancreatitis during treatment. If pancreatitis is suspected, treatment should be discontinued immediately and appropriate management should be initiated.
References (4)
- (2006) "Product Information. Januvia (sitagliptin)." Merck & Co., Inc
- (2009) "Product Information. Onglyza (saxagliptin)." Bristol-Myers Squibb
- (2011) "Product Information. Tradjenta (linagliptin)." Boehringer Ingelheim
- (2013) "Product Information. Nesina (alogliptin)." Takeda Pharmaceuticals America
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Linagliptin drug interactions
There are 349 drug interactions with linagliptin.
Linagliptin alcohol/food interactions
There is 1 alcohol/food interaction with linagliptin.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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