Siliq (brodalumab) Disease Interactions
There are 2 disease interactions with Siliq (brodalumab):
Brodalumab (Includes Siliq) ↔ Crohn's disease
Severe Potential Hazard, Moderate plausibility. Applies to: Inflammatory Bowel Disease
The use of brodalumab is contraindicated in patients with Crohn's disease as this agent may cause worsening of the disease. It is recommended to discontinue the use of brodalumab if patients develop Crohn's disease while on treatment.
Brodalumab (Includes Siliq) ↔ depression
Severe Potential Hazard, Moderate plausibility. Applies to: Depression
Suicidal ideation and behavior, including completed suicides, have occurred in patients treated with brodalumab. Patients with depression and other psychiatric disorders may experience worsening of their symptoms and may have the emergence of suicidal thoughts and behavior. Patients should be monitored appropriately and observed closely for worsening of their symptoms, suicidality or changes in their behavior. Prescribers should weigh the potential risks and benefits before using brodalumab in patients with a history of depression or suicidality. Families and caregivers should be advised of the need for close observation and communication with the treating physician.
Siliq (brodalumab) drug interactions
There are 110 drug interactions with Siliq (brodalumab)
More about Siliq (brodalumab)
- Siliq Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- 7 Reviews
- Drug class: interleukin inhibitors
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
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