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Solganal (aurothioglucose) Disease Interactions

There is 1 disease interaction with Solganal (aurothioglucose):

Major

Auranofin (Includes Solganal) ↔ bone marrow aplasia

Severe Potential Hazard, High plausibility. Applies to: Bone Marrow Depression/Low Blood Counts

The use of auranofin and other gold compounds is contraindicated in patients with a history of gold- induced bone marrow aplasia. Prior to gold compounds therapy, a complete blood count with a differential, platelet count, urinalysis, and renal and liver function tests should be performed. A complete blood count with a differential, platelet count, and urinalysis should be done at least monthly during therapy. Hematological warning signs of gold toxicity include a drop in hemoglobin, leukopenia (WBC < 4,000/mm3), granulocytopenia (< 1,500/mm3), and thrombocytopenia (<100,000/mm3).

References

  1. "Product Information. Ridaura (auranofin)." SmithKline Beecham, Philadelphia, PA.
  2. "Product Information. Solganal (aurothioglucose)." Schering Laboratories, Kenilworth, NJ.
  3. "Product Information. Myochrysine (gold sodium thiomaleate)." Merck & Co, Inc, West Point, PA.

Solganal (aurothioglucose) drug interactions

There are 140 drug interactions with Solganal (aurothioglucose)

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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