Generic Name: tedizolid (Intravenous route)
Medically reviewed by Drugs.com. Last updated on Apr 12, 2019.
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Antibacterial
Chemical Class: Oxazolidinone
Uses for Sivextro
Tedizolid injection is used to treat acute bacterial skin and skin structure infections (ABSSSI). It belongs to the class of drugs called antibiotics. Tedizolid works by killing bacteria or preventing their growth.
This medicine is to be given only by or under the direct supervision of your doctor.
Before using Sivextro
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of tedizolid injection in the pediatric population. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of tedizolid injection in the elderly.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Cholera Vaccine, Live
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Diarrhea—Use with caution. May make this condition worse.
- Neutropenia (low white blood cell count)—Tedizolid may not work as well in patients with this condition.
Proper use of Sivextro
A nurse or other trained health professional will give you this medicine in a medical facility. It is given through a needle placed into one of your veins.
This medicine should come with a patient information leaflet. Read and follow these instructions carefully. Ask your doctor if you have any questions.
Precautions while using Sivextro
It is very important that your doctor check your progress closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to check for any unwanted effects.
This medicine may cause diarrhea, and in some cases it can be severe. It may also occur 2 months or more after you stop receiving this medicine. If you have diarrhea that continues or gets worse, check with your doctor. Do not take any medicine to treat diarrhea without checking first with your doctor.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Sivextro side effects
Check with your doctor or nurse immediately if any of the following side effects occur:
- Blurred vision
- chest tightness
- fast, pounding, or irregular heartbeat or pulse
- hives or welts, itching, or skin rash
- itching of the vagina or genitals
- joint pain, stiffness, or swelling
- pale skin
- pounding in the ears
- redness of the skin
- severe abdominal or stomach cramps and pain
- slow or fast heartbeat
- sore mouth or tongue
- stomach tenderness
- swelling of the eyelids, face, lips, hands, or feet
- thick, white vaginal discharge with mild or no odor
- tightness in the chest
- troubled breathing or swallowing
- troubled breathing with exertion
- unusual bleeding or bruising
- unusual tiredness or weakness
- watery or severe diarrhea, which may also be bloody
- white patches in the mouth or on the tongue
Incidence not known
- Black, tarry stools
- blood in the urine or stools
- lower back or side pain
- painful or difficult urination
- pinpoint red spots on the skin
- Bleeding, blistering, burning, discoloration of the skin, infection, itching, lumps, numbness, pain, redness, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
- burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- double vision
- feeling of warmth
- feeling that you cannot keep your eyes open
- increased sensitivity of the eyes to light
- redness of the face, neck, arms, and occasionally, upper chest
- seeing floating spots before the eyes
- sore neck, shoulders, or back
- sore, tired, burning, or itching eyes
- trouble concentrating
- trouble sleeping
- watery or dry eyes
Copyright 2020 Truven Health Analytics, Inc. All Rights Reserved.
More about Sivextro (tedizolid)
- Side Effects
- During Pregnancy
- Dosage Information
- Imprints, Shape & Color Data
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: oxazolidinone antibiotics
- FDA Approval History