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Medications for Macular Degeneration

Macular degeneration is a disorder that affects the macula (the central part of the retina of the eye) causing decreased visual acuity and possible loss of central vision.

Drugs used to treat Macular Degeneration

The following list of medications are in some way related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Eylea 6.4 23 reviews
Rx C N

Generic name: aflibercept ophthalmic

Drug class: anti-angiogenic ophthalmic agents

For consumers: dosage, side effects

For professionals: Prescribing Information

Lucentis 7.5 7 reviews
Rx C N

Generic name: ranibizumab ophthalmic

Drug class: anti-angiogenic ophthalmic agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Beovu 10 1 review
Rx N

Generic name: brolucizumab systemic

Drug class: anti-angiogenic ophthalmic agents

For consumers: dosage, side effects

For professionals: Prescribing Information

ranibizumab 7.7 8 reviews
Rx C N

Generic name: ranibizumab ophthalmic

Brand names:  Lucentis, Byooviz, Susvimo

Drug class: anti-angiogenic ophthalmic agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

bevacizumab Off-label 10 4 reviews
Rx C N

Generic name: bevacizumab systemic

Drug class: VEGF/VEGFR inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

Off-label: Yes

brolucizumab 10 1 review
Rx N

Generic name: brolucizumab systemic

Brand name:  Beovu

Drug class: anti-angiogenic ophthalmic agents

For consumers: dosage, side effects

For professionals: AHFS DI Monograph

Visudyne Rate Add review
Rx C N X

Generic name: verteporfin systemic

Drug class: miscellaneous antineoplastics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

aflibercept 6.1 25 reviews
Rx C N

Generic name: aflibercept ophthalmic

Brand name:  Eylea

Drug class: anti-angiogenic ophthalmic agents

For consumers: dosage, side effects

For professionals: AHFS DI Monograph

verteporfin Rate Add review
Rx C N X

Generic name: verteporfin systemic

Brand name:  Visudyne

Drug class: miscellaneous antineoplastics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

Byooviz Rate Add review
Rx C N

Generic name: ranibizumab ophthalmic

Drug class: anti-angiogenic ophthalmic agents

For consumers: dosage, interactions, side effects

Susvimo Rate Add review
Rx C N

Generic name: ranibizumab ophthalmic

Drug class: anti-angiogenic ophthalmic agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

faricimab Rate Add review
Rx U

Generic name: faricimab systemic

Brand name:  Vabysmo

For consumers: side effects

For professionals: AHFS DI Monograph

Vabysmo Rate Add review
Rx U

Generic name: faricimab systemic

For consumers: dosage, side effects

For professionals: Prescribing Information

Learn more about Macular Degeneration

Care guides

Symptoms and treatments

Medicine.com guides (external)

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.