Faricimab Ophthalmic Side Effects
Medically reviewed by Drugs.com. Last updated on May 14, 2024.
Applies to faricimab ophthalmic: intraocular solution.
Precautions
Your eye doctor will want to check your progress at regular visits, especially during the first few days after you receive this medicine, to make sure this medicine is working properly and to check for unwanted effects.
Receiving this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant during treatment and for at least 3 months after the last dose. If you think you have become pregnant while receiving this medicine, tell your doctor right away.
Serious eye or vision problems (eg, eye infection, retinal detachment, retinal vasculitis, or retinal vascular occlusion) may occur with this medicine. Check with your eye doctor right away if your have blurred or other change in vision, eye pain, eye redness, headache, seeing flashes or sparks of light, seeing floating spots before the eyes, or a veil or curtain appearing across part of vision, or tearing of the eyes several days after you receive this medicine. Also, tell your eye doctor if you feel increased pressure in your eye.
This medicine may increase your risk of blood clots, heart attack, or stroke. Check with your doctor right away if you are having pain in your chest, groin, or legs, especially the calves, difficulty or trouble breathing, a severe, sudden headache, slurred speech, sudden loss of coordination, sudden, severe weakness or numbness in your arm or leg, or vision changes.
This medicine may cause temporary blurred vision. Do not drive or do anything else that could be dangerous until you can see clearly.
Serious side effects
Along with its needed effects, faricimab ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking faricimab ophthalmic:
More common side effects
- bloody eye
- redness of the eye
Less common side effects
- blurred vision
- change in vision
- eye pain
- loss of vision
- red, sore eyes
- seeing floaters, veil or curtain appearing across part of vision
- seeing floating dark spots or material before the eyes
- tearing
Rare side effects
- eye irritation
- seeing light flashes
- watering of the eyes
Incidence not known
- chest pain, discomfort, or tightness
- fast heartbeat
- fever
- hives, itching, rash
- hoarseness
- irritation
- joint pain, stiffness, or swelling
- nausea
- pain or discomfort in the arms, jaw, back, or neck
- redness of the skin
- stroke
- sweating
- swelling of the eyelids, face, lips, hands, or feet
- trouble breathing
- vomiting
For healthcare professionals
Applies to faricimab ophthalmic: intravitreal solution.
Cardiovascular adverse events
- Common (1% to 10%): Arterial thromboembolic events (defined as nonfatal stroke, nonfatal myocardial infarction, vascular death [including deaths of unknown cause])[Ref]
In the neovascular age-related macular degeneration studies, arterial thromboembolic events were reported in 1% of patients during the first year. In the diabetic macular edema studies, arterial thromboembolic events were reported in 2% of patients during the first year.[Ref]
Hypersensitivity
- Frequency not reported: Hypersensitivity reactions[Ref]
Immunologic
- Very common (10% or more): Anti-drug antibodies (up to 10.4%)[Ref]
Ocular
- Very common (10% or more): Cataract (10.7%)
- Common (1% to 10%): Conjunctival hemorrhage, eye pain, increased intraocular pressure, increased lacrimation, retinal pigment epithelial tear, vitreous floaters
- Uncommon (0.1% to 1%): Blurred vision, corneal abrasion, conjunctival hyperemia, endophthalmitis, eye irritation, eye pruritus, iridocyclitis, iritis, ocular discomfort, ocular hyperemia, retinal tear, sensation of foreign body, uveitis, reduced visual acuity, vitreous hemorrhage, vitritis
- Rare (0.01% to 0.1%): Rhegmatogenous retinal detachment, transiently reduced visual acuity[Ref]
See also:
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Syfovre
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Eylea
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Ozurdex
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Aflibercept ophthalmic
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Fluocinolone ophthalmic
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Triamcinolone ophthalmic
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References
1. (2022) "Product Information. Vabysmo (faricimab ophthalmic)." Genentech
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Further information
Faricimab ophthalmic side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.