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Visudyne

Generic Name: verteporfin (VER te PORE fin)
Brand Name: Visudyne

What is Visudyne?

Visudyne works by enhancing the eye's sensitivity to light. This medicine affects abnormal blood vessels in the eye.

Visudyne is used together with "photodynamic" laser light therapy to treat blood vessel disorders in the eye caused by macular degeneration and other eye diseases.

Visudyne may also be used for purposes not listed in this medication guide.

Important Information

You should not receive this medicine if you have porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).

Before taking this medicine

You should not receive Visudyne if you are allergic to it, or if you have porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).

To make sure Visudyne is safe for you, tell your doctor if you have:

FDA pregnancy category C. It is not known whether Visudyne will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

Verteporfin can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using verteporfin.

How is verteporfin given?

Visudyne is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. This medicine must be given slowly, and the IV infusion can take at least 10 minutes to complete.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Visudyne is injected.

You will receive laser light treatment to your eye(s) within 15 minutes after the start of your Visudyne infusion.

After receiving Visudyne, you must protect your eyes from natural sunlight and bright indoor light for at least 5 days.. For best protection, wear dark sunglasses whenever you are outdoors or while indoors under bright lighting.

You should not stay in the dark while you are indoors, as this can actually cause the drug to stay active in your body longer. It is best to spend your time in ambient indoor light such as indirect sunlight through a window, or low-wattage incandescent lighting. Avoid areas where you will be exposed to halogen or fluorescent light.

Your doctor will need to check your progress on a regular basis. Do not miss any scheduled appointments.

What happens if I miss a dose?

Since Visudyne is given by a healthcare professional only in preparation for laser light treatment, you will not be on a frequent dosing schedule.

Your doctor should check your condition every 3 months to determine if you need repeat treatment.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severely decreased vision.

What should I avoid after I receive Visudyne?

Visudyne will make your eyes and your skin more sensitive to light. Natural sunlight and bright indoor light can expose you to harmful UV rays, which may cause severe sunburn or damage to your vision.

Avoid exposure to sunlight, tanning beds, bright halogen lights, or other bright lighting for at least 5 days after you are treated with Visudyne.

To avoid exposing your skin to sunlight, keep all parts of your skin covered with clothing. Sunscreen will not be effective in protecting you from UV rays during the 5-day period after you have received Visudyne.

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Visudyne side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; sweating; dizziness; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have:

  • severe decrease in vision;

  • sudden and severe pain;

  • severe redness or other discoloration of your eyes;

  • eye pain or seeing halos around lights;

  • feeling like you might pass out;

  • chest pain; or

  • flushing (warmth, redness, or tingly feeling).

Common side effects may include:

  • slight changes in your vision, seeing flashes of light;

  • dry eyes;

  • redness, swelling, or itching of your eyelids;

  • headache, feeling weak or tired;

  • mild itching or skin rash;

  • constipation, nausea;

  • joint pain, muscle weakness;

  • fever, chills, flu symptoms; or

  • pain, swelling, bleeding, or itching where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Visudyne?

Other drugs may interact with verteporfin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

This list is not complete and other drugs may interact with Visudyne. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

  • Your doctor or pharmacist can provide more information about Visudyne.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 2.03.

Date modified: January 03, 2018
Last reviewed: July 15, 2014

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