Generic Name: verteporfin (Intravenous route, Injection route)
Medically reviewed by Drugs.com. Last updated on Sep 26, 2019.
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Photosensitizing Agent
Uses for Visudyne
Verteporfin is used together with a special laser light, to treat abnormal blood vessel formation in a part of the eye which, if left untreated, can lead to a loss of eyesight.
Verteporfin may also be used for the following problems:
- Pathologic myopia (changes in the eyeball causing vision problems);
- Ocular histoplasmosis (damage to the eye from a fungus found in the soil)
This medicine is to be administered only by or under the immediate supervision of your doctor.
Before using Visudyne
Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of verteporfin in children with use in other age groups.
Studies show that the effects of verteporfin are less in patients 75 years of age or older.
|All Trimesters||C||Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.|
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Other medical problems
- Liver function impairment
- Porphyria—Sensitivity to light may be increased
- Previous reaction to verteporfin—Reaction is more likely to occur again
Proper use of Visudyne
Treatment with verteporfin and laser light occurs in two steps. First, the verteporfin is injected into your body. Second, 15 minutes later, a laser light is directed at the affected eye.
Precautions while using Visudyne
For 5 days after you receive an injection of verteporfin, your eyes will be extra sensitive to light, including sunlight and bright indoor lights. Certain types of sunglasses can help protect your eyes during this time. Check with your doctor about which sunglasses to use.
For 5 days after you receive an injection of verteporfin, your skin will be extra sensitive to sunlight and to very bright indoor lights, such as tanning lamps, bright halogen lighting and lights in dental offices or operating rooms. Do not expose your skin to direct sunlight or to bright indoor lights during this time. Sunscreens will not protect your skin from a severe reaction to light (blistering, burning, and swelling of the skin). However, exposure to normal amounts of indoor light (for example, daylight or light from lamps with shades) will help clear up the verteporfin remaining in your skin. Therefore, do not protect your skin from normal amounts of indoor light. If you have any questions about whether the light in your home is too bright, check with your doctor or nurse. If you do have a severe reaction to light, call your doctor immediately.
Visudyne side effects
Check with your doctor immediately if any of the following side effects occur:
- Blurred vision or other change in vision
- Decrease in vision, may be severe
- dull nervousness
- eye pain
- fast, slow, or irregular heartbeat
- itching, redness, or other irritation of eye
- pale skin
- pounding in the ears
- troubled breathing on exertion
- unusual bleeding or bruising
- unusual tiredness or weakness
- Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, infection, itching, numbness, pain, rash, redness, scarring, stinging, swelling, tenderness, tingling, ulceration, and/or warmth at the injection site
- Back pain (during infusion of verteporfin)
- cloudy urine
- decreased hearing
- decreased sensitivity to touch
- difficult or painful urination
- difficulty in moving
- double vision
- dry eyes
- feeling of constant movement of self or surroundings
- general feeling of discomfort or illness
- increased sensitivity of skin to sunlight
- joint pain
- light headedness
- loss of appetite
- loss of strength or energy
- muscle pain or stiffness
- pain, swelling, or redness in joints
- pelvic discomfort
- redness or other discoloration of skin
- runny nose
- severe sunburn
- skin rash
- sore throat
- tender, swollen glands in neck
- throat congestion
- trouble in sleeping
- trouble in swallowing
- trouble sleeping
- varicose veins
- voice changes
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More about Visudyne (verteporfin)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: miscellaneous antineoplastics