Comparing Rexulti vs Wellbutrin XL
| Rexulti (brexpiprazole) | Wellbutrin XL (bupropion) |
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| Rexulti (brexpiprazole) | Wellbutrin XL (bupropion) |
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Prescription only
Rexulti is an atypical antipsychotic that may be used to treat adults with schizophrenia or depression, or used to relieve agitation associated with dementia in Alzheimer's disease. Most people... View more |
Prescription only
Prescribed for Major Depressive Disorder, Depression, Seasonal Affective Disorder. Wellbutrin XL may also be used for purposes not listed in this medication guide. |
Related suggestions Depression
Major Depressive Disorder
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| More about Rexulti (brexpiprazole) | More about Wellbutrin XL (bupropion) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Rexulti has an average rating of 6.6 out of 10 from a total of 497 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 25% reported a negative effect. |
Wellbutrin XL has an average rating of 7.5 out of 10 from a total of 493 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 16% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Rexulti side effects |
View all Wellbutrin XL side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Rexulti prices |
View all Wellbutrin XL prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Other bupropion brands include: Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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91 hours |
30 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 601 drugs are known to interact with Rexulti:
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A total of 559 drugs are known to interact with Wellbutrin XL:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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July 10, 2015 |
August 28, 2003 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.