Comparing Rexulti vs Wellbutrin XL

For Major Depressive Disorder Mixed bag. On the positive side, it can pull you out of a dark hole really quick. On the negative, I'm starting to suspect it is causing a lot of my anger and irritation symptoms to go off the charts. I'm going to try going off of it for a few days again and if that makes me feel better, time to call my doc for something else.

For Major Depressive Disorder I have been on Rexulti for a little over a month now and it has basically been a godsend. The first week or two I cried nonstop at almost anything. Happy things. Sad things. Funny things. It was more of a delusional cry than a depressive/sad cry. It was really annoying but went away after about 1-2 weeks. I have not gained any weight, which I’m super thankful for. The only side effect I've really had is the fatigue. I’m so tired every single day that I’ve started taking naps. I never take naps. I’ve also started drinking coffee in the mornings to keep myself awake. I’ve also never been a coffee drinker. These two things are starting to worry me a bit because it’s almost interfering with my schoolwork and daily function. But I love this medication otherwise and don’t want to consider anything else if it’s really helping me.

For Depression After being on several medications and therapy for over a year and experiencing numerous suicidal thoughts, I had given up on life. I read reviews on here of people saying “be patient and your life will change.” My life never changed and I was stuck in the same lifeless routine everyday. I now take 187.5mg of Effexor XR with 150 Wellbutrin XR, and trust me it took months for things to improve but everything changed. Suddenly life didn’t seem so awful. I began making goals for myself, and I wanted to get up and be active instead of sleeping my depression away. I do get slightly depressed here and there but nothing so bad that I would want to end my life. Please don’t give up hope... reach out to someone you love and trust, they will help you get through this difficult time. And be patient even if it takes two years. It took me almost two years of suffering to get to where I am now. There is light at the end of the tunnel :) feel free to ask any questions you might have.

For Depression 26 year old male. Been on it for 31 days. 1st week 150mg xl: high speedy energy. Mild insomnia (up till 3am most nights). Waking early and generally good mood. 2nd week 300mg xl. Very high constant anxiety. Emotional swings. Broke down in tears one day. 3rd week: Things were smoothing out. Still slightly anxious. Less emotional. 4th week: Feeling completely normal almost like I'm not on any medication. More level headed and better mood with less swings. Anxiety disappearing and confidence growing. No side effects. This is in combination with seeking help from a counselor, and confiding with a close friend of mine about how depressed I have been over the years. I am happy I took it. It has got me back on my feet and allowed me to seek help.