Comparing Mounjaro vs Xigduo XR

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Mounjaro (tirzepatide)	Xigduo XR (dapagliflozin / metformin)	Enter another drug to compare

Mounjaro (tirzepatide)

Xigduo XR (dapagliflozin / metformin)

Prescription only

Prescribed for Weight Loss (Obesity/Overweight), Type 2 Diabetes. Mounjaro may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Heart Failure, Type 2 Diabetes. Xigduo XR may also be used for purposes not listed in this medication guide.

More about Mounjaro (tirzepatide)

More about Xigduo XR (dapagliflozin / metformin)

Ratings & Reviews

Mounjaro has an average rating of 8.5 out of 10 from a total of 1397 ratings on Drugs.com. 79% of reviewers reported a positive effect, while 6% reported a negative effect.

Xigduo XR has an average rating of 7.3 out of 10 from a total of 17 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 24% reported a negative effect.

View all 1397 reviews

View all 17 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Nausea (16.5%)
Constipation (11.5%)
Diarrhea (8.2%)
Upset stomach (4.7%)
Loss of appetite (4.6%)
Vomiting (4.5%)
Burping (4.0%)

View all Mounjaro side effects

View all Xigduo XR side effects

Drug Class

GLP-1 Agonists (Incretin Mimetics)

Antidiabetic combinations

Generic Availability

No lower cost generic approved

Pricing and Coupons * Prices are without insurance

Quantity	2 mL
Strength	2.5 mg/0.5 mL
Per unit^*	$581.34
Cost^*	$1,162.67

View all Mounjaro prices

Quantity	60 tablet, extended release
Strength	5 mg-1000 mg
Per unit^*	$10.84
Cost^*	$650.21

View all Xigduo XR prices

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Dosage Forms

Subcutaneous solution

Oral tablet, extended release

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

120 hours

12.9 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Summary unavailable.

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 415 drugs are known to interact with Mounjaro:

15 major drug interactions (34 brand and generic names)
399 moderate drug interactions (2278 brand and generic names)
1 minor drug interactions (10 brand and generic names)

A total of 479 drugs are known to interact with Xigduo XR:

25 major drug interactions (136 brand and generic names)
442 moderate drug interactions (2110 brand and generic names)
12 minor drug interactions (42 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Tirzepatide may affect the absorption of other medications that you take by mouth. In some cases... View more
Talk to your doctor before using alcohol together with tirzepatide. Alcohol may affect blood... View more

MetFORMIN should be taken with meals, and excessive alcohol intake (either short-term binge... View more

Disease Interactions

First Approval Date

N/A

October 29, 2014

WADA Class View classifications

N/A

More Information

Patient Resources

Mounjaro uses

Xigduo XR uses

Professional Resources

Prescribing information

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Mounjaro vs Xigduo XR

See also:

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Zepbound

Ozempic

Wegovy

Victoza

Contrave

Saxenda

Alli

Amphetamine

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Further information

Comparing Mounjaro vs Xigduo XR

See also:

Further information

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