Comparing Minoxidil Topical vs Spironolactone

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
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Minoxidil topical

Spironolactone

Prescribed for Alopecia. minoxidil topical may also be used for purposes not listed in this medication guide.

Spironolactone is a diuretic that may be used to remove excess fluid (edema) from the body, lower blood pressure, or treat hyperaldosteronism. It does not cause potassium loss from the body; however... View more

Prescription and OTC

Prescription only

Pricing and Coupons

* Prices are without insurance

Quantity	60 mL
Dosage	5%
Per Unit^*	$0.52
Cost^*	$30.92

View all minoxidil topical prices

Quantity	100 each
Dosage	25 mg
Per Unit^*	$0.23
Cost^*	$23.28

View all spironolactone prices

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Generic Availability

Yes (this medicine)

Dosage Form(s) Available

Topical foam
Topical solution

Oral tablet

Brand Names

Hair Regrowth Treatment for Men, Hair Regrowth Treatment for Women, Rogaine, Rogaine Extra Strength, Rogaine Men's Extra Strength, Rogaine Women's Aldactone, CaroSpir

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

N/A

37 hours

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Drug Interactions

A total of 37 drugs are known to interact with minoxidil topical:

37 moderate drug interactions (132 brand and generic names)

A total of 354 drugs are known to interact with spironolactone:

49 major drug interactions (234 brand and generic names)
282 moderate drug interactions (1339 brand and generic names)
23 minor drug interactions (192 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Spironolactone and alcohol may have additive effects in lowering your blood pressure. You may... View more

Disease Interactions

Systemic effects

First Approval Date

August 17, 1988

January 21, 1960

WADA Class

View World Anti-Doping Agency classifications.

N/A

S5 - Diuretics and Other Masking Agents

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

Alopecia

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer