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Comparing Lupron Depot-PED vs Tamoxifen

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Lupron Depot-PED Remove Lupron Depot-PED from your drug comparison	Tamoxifen Remove Tamoxifen from your drug comparison	Add another drug to compare

Lupron Depot-PED leuprolide

Tamoxifen

Prescribed for Precocious Puberty. Lupron Depot-PED may also be used for purposes not listed in this medication guide.

Prescribed for Breast Cancer - Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Breast Cancer - Male, Breast Cancer - Palliative, McCune-Albright Syndrome, Precocious Puberty. May also be... View more

Prescription only

Ratings & Reviews

View all 23 reviews

View all 83 reviews

Drug Class

Side Effects

See the full Lupron Depot-PED side effects document.

Commonly reported side effects include: amenorrhea, fluid retention, hot flash, nausea, vaginal discharge, vaginal hemorrhage, weight loss, and skin changes.

See the full tamoxifen side effects document.

Pricing and Coupons

* Prices are without insurance

Quantity	1 kit
Dosage	7.5 mg/month
Per Unit^*	$1,872.29
Cost^*	$1,872.29

View all Lupron Depot-PED prices and generic prices

Quantity	100 each
Dosage	10 mg
Per Unit^*	$0.44
Cost^*	$44.19

View all tamoxifen prices

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Generic Availability

Yes

Yes (this medicine)

Dosage Form(s) Available

Intramuscular kit
Intramuscular powder for injection, extended release

Oral tablet

Brand Names

Other leuprolide brands include: Eligard, Fensolvi, Lupron Depot Soltamox

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

4.25 hours

231 hours

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category X Not for use in pregnancy

See the full Pregnancy Warnings document.

Category D Positive evidence of risk

See the full Pregnancy Warnings document.

FDA Alerts

N/A

Drug Interactions

A total of 259 drugs are known to interact with Lupron Depot-PED:

53 major drug interactions (145 brand and generic names)
204 moderate drug interactions (788 brand and generic names)
2 minor drug interactions (11 brand and generic names)

A total of 375 drugs are known to interact with tamoxifen:

99 major drug interactions (373 brand and generic names)
267 moderate drug interactions (877 brand and generic names)
9 minor drug interactions (33 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Talk to your doctor before using tamoxifen with soy products. There is some evidence that... View more

Disease Interactions

First Approval Date

N/A

December 30, 1977

WADA Class

View World Anti-Doping Agency classifications.

N/A

S4 - Hormone and Metabolic Modulators

More Information

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer