Comparing Insulin Glargine vs Novolog

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Insulin glargine	Novolog (insulin aspart)	Enter another drug to compare

Insulin glargine

Novolog (insulin aspart)

Prescription only

Prescribed for Type 2 Diabetes, Diabetes - Type 1. Insulin glargine may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Type 2 Diabetes, Diabetes - Type 1, Diabetic Ketoacidosis, Nonketotic Hyperosmolar Syndrome. Novolog may also be used for purposes not listed in this medication guide.

More about Insulin glargine

More about Novolog (insulin aspart)

Ratings & Reviews

Insulin glargine has an average rating of 4.2 out of 10 from a total of 293 ratings on Drugs.com. 25% of reviewers reported a positive effect, while 56% reported a negative effect.

Novolog has an average rating of 5.5 out of 10 from a total of 32 ratings on Drugs.com. 31% of reviewers reported a positive effect, while 34% reported a negative effect.

View all 293 reviews

View all 32 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Headaches (6.5%)
Weight gain (5.8%)
Pain (4.4%)
Swelling (4.4%)
Rash (3.4%)
Anxiety (3.1%)
Blood sugar (3.1%)

View all Insulin glargine side effects

View all Novolog side effects

Drug Class

Insulin

Insulin

Generic Availability

Lower cost generic

N/A

Pricing and Coupons * Prices are without insurance

Quantity	10 mL
Strength	yfgn 100 units/mL
Per unit^*	$7.72
Cost^*	$77.22

View all Insulin glargine prices

Quantity	10 mL
Strength	100 units/mL
Per unit^*	$8.72
Cost^*	$87.23

View all Novolog prices

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Dosage Forms

Subcutaneous solution

Injectable solution
Subcutaneous solution

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

24 hours

1.5 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category B No proven risk in humans

See the full pregnancy warnings document.

Drug Interactions

A total of 394 drugs are known to interact with Insulin glargine:

15 major drug interactions (39 brand and generic names)
358 moderate drug interactions (1888 brand and generic names)
21 minor drug interactions (210 brand and generic names)

A total of 394 drugs are known to interact with Novolog:

15 major drug interactions (39 brand and generic names)
358 moderate drug interactions (1888 brand and generic names)
21 minor drug interactions (210 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood... View more

Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood... View more

Disease Interactions

First Approval Date

April 20, 2000

June 07, 2000

WADA Class View classifications

N/A

More Information

Patient Resources

Novolog uses

Professional Resources

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Insulin Glargine vs Novolog

See also:

Ozempic

Rybelsus

Mounjaro

Trulicity

Lantus

Tresiba

Victoza

Basaglar

Humalog

Levemir

Further information

Comparing Insulin Glargine vs Novolog

See also:

Further information

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