Comparing Estradiol Topical vs Ospemifene
| Estradiol topical | Ospemifene |
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| Estradiol topical | Ospemifene |
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Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis, Overactive Bladder, Dyspareunia. Estradiol topical may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Dyspareunia, Vaginal Dryness, Atrophic Vaginitis, Perimenopausal Symptoms, Postmenopausal Symptoms. Ospemifene may also be used for purposes not listed in this medication guide. |
Related suggestions Atrophic Vaginitis
Dyspareunia
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| More about Estradiol topical | More about Ospemifene | ||||||||
| Ratings & Reviews | |||||||||
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Estradiol topical has an average rating of 5.1 out of 10 from a total of 491 ratings on Drugs.com. 37% of reviewers reported a positive effect, while 45% reported a negative effect. |
Ospemifene has an average rating of 5.3 out of 10 from a total of 45 ratings on Drugs.com. 36% of reviewers reported a positive effect, while 40% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Estradiol topical side effects |
View all Ospemifene side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||
View all Estradiol topical prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
| Estrace Vaginal Cream, Estring, Imvexxy, Vagifem, Yuvafem | Osphena | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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N/A |
26 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 260 drugs are known to interact with Estradiol topical:
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A total of 98 drugs are known to interact with Ospemifene:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||
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| First Approval Date | |||||||||
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January 31, 1984 |
February 26, 2013 |
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| WADA Class View classifications | |||||||||
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N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.