Comparing Estradiol Topical vs Estrogel
| Estradiol topical | Estrogel (estradiol) |
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| Estradiol topical | Estrogel (estradiol) |
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Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis, Overactive Bladder, Dyspareunia. Estradiol topical may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Atrophic Vaginitis, Postmenopausal Symptoms, Atrophic Urethritis. Estrogel may also be used for purposes not listed in this medication guide. |
Related suggestions Atrophic Vaginitis
Atrophic Urethritis
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| More about Estradiol topical | More about Estrogel (estradiol) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Estradiol topical has an average rating of 5.1 out of 10 from a total of 489 ratings on Drugs.com. 37% of reviewers reported a positive effect, while 45% reported a negative effect. |
Be the first to share your experience with this drug. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Estradiol topical side effects |
View all Estrogel side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Estradiol topical prices |
View all Estrogel prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Estrace Vaginal Cream, Estring, Imvexxy, Vagifem, Yuvafem | Other estradiol brands include: Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estrace, Estraderm, Estradiol Patch, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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N/A |
16 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 258 drugs are known to interact with Estradiol topical:
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A total of 390 drugs are known to interact with Estrogel:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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January 31, 1984 |
February 09, 2004 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.