Comparing Esmolol vs Propranolol

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Esmolol	Propranolol	Enter another drug to compare

Esmolol

Propranolol

Prescription only

Prescribed for Supraventricular Tachycardia, High Blood Pressure, Intra- or Post-op SVT or Hypertension, Atrial Fibrillation, Atrial Flutter. Esmolol may also be used for purposes not listed in this... View more

Prescription only

Propranolol is mainly used for blood pressure and angina control; however, it also has a role in migraine prevention and the treatment of essential tremor. Propranolol may cause vivid dreams and is... View more

More about Esmolol

More about Propranolol

Ratings & Reviews

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Propranolol has an average rating of 8.2 out of 10 from a total of 1382 ratings on Drugs.com. 77% of reviewers reported a positive effect, while 12% reported a negative effect.

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Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Esmolol side effects

Tremors (10.4%)
Anxiety (6.7%)
Tiredness (6.7%)
Increased heart rate (6.4%)
Dizziness (5.1%)
Sweating (4.8%)
Headaches (4.1%)

View all Propranolol side effects

Drug Class

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	100 mL
Strength	10 mg/mL
Per unit^*	$0.71
Cost^*	$71.25

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Quantity	50 each
Strength	20 mg
Per unit^*	$0.35
Cost^*	$17.39

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Dosage Forms

Intravenous solution

Intravenous solution
Oral capsule, extended release
Oral solution
Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

1 hour

6.4 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 413 drugs are known to interact with Esmolol:

28 major drug interactions (134 brand and generic names)
365 moderate drug interactions (1626 brand and generic names)
20 minor drug interactions (160 brand and generic names)

A total of 591 drugs are known to interact with Propranolol:

47 major drug interactions (215 brand and generic names)
494 moderate drug interactions (3307 brand and generic names)
50 minor drug interactions (612 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Esmolol and alcohol may have additive effects in lowering your blood pressure. You may experience... View more

Food can enhance the levels of propranolol in your body. You shoud take propranolol at the same... View more

Disease Interactions

First Approval Date

April 07, 2016

November 13, 1967

WADA Class View classifications

P1 - Beta-Blockers

P1 - Beta-Blockers

More Information

Patient Resources

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Esmolol vs Propranolol

See also:

Cardizem

Adenocard

Ozempic

Pacerone

Zebeta

Brevibloc

Adenosine

Phenylephrine

Flecainide

Bisoprolol

Further information

Comparing Esmolol vs Propranolol

See also:

Further information

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