Comparing Differin vs Duac
| Differin (adapalene) | Duac (benzoyl peroxide / clindamycin) |
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| Differin (adapalene) | Duac (benzoyl peroxide / clindamycin) |
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Prescription and OTC
Prescribed for Acne. Differin may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Acne. Duac may also be used for purposes not listed in this medication guide. |
Related suggestions |
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| More about Differin (adapalene) | More about Duac (benzoyl peroxide / clindamycin) | ||||||||
| Ratings & Reviews | |||||||||
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Differin has an average rating of 6.1 out of 10 from a total of 345 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 36% reported a negative effect. |
Duac has an average rating of 7.3 out of 10 from a total of 279 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 17% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Differin side effects |
View all Duac side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||
View all Differin prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Other adapalene brands include: Plixda | Other benzoyl peroxide / clindamycin brands include: Acanya, Benzaclin, Neuac, Onexton, Z-Clinz 10 | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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51 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 12 drugs are known to interact with Differin:
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A total of 21 drugs are known to interact with Duac:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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May 31, 1996 |
August 26, 2002 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.