Differin Disease Interactions
There are 2 disease interactions with Differin (adapalene topical).
Retinoid/retinoid-like topical (applies to Differin) eczema
Major Potential Hazard, High plausibility.
Topical retinoids may cause severe irritation on eczematous skin. Therapy with topical retinoids should be avoided on abraded or eczematous skin.
Retinoid/retinoid-like topical (applies to Differin) sunburn
Moderate Potential Hazard, High plausibility.
Retinoid-like products can cause extreme irritation when applied to sunburned skin. Patients with sunburn should be cautioned not to use retinoid-like acne products until fully recovered, and to avoid prolonged exposure to sunlight (including sunlamps) and use sunscreen/protective clothing during treatment with these products.
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Differin drug interactions
There are 12 drug interactions with Differin (adapalene topical).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.