Comparing Clonidine vs Sinemet
Clonidine | Sinemet |
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Clonidine | Sinemet (carbidopa / levodopa) |
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Prescription only
Clonidine can be used to lower blood pressure and treat ADHD; however, it causes sedation, and tolerance can develop to its blood pressure-lowering effects. Clonidine should not be stopped suddenly... View more |
Prescription only
Sinemet is a medication that may be used for the treatment of Parkinson's disease that is available in three different strengths: Sinemet 25/100, Sinemet 25/250, and Sinemet 10/100. Dyskinesias... View more |
Related suggestions Restless Legs Syndrome
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More about Clonidine | More about Sinemet (carbidopa / levodopa) | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Clonidine has an average rating of 7.2 out of 10 from a total of 756 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 21% reported a negative effect. |
Sinemet has an average rating of 7.8 out of 10 from a total of 30 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 11% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: clonidine side effects in more detail. |
See also: Sinemet side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all clonidine prices |
View all Sinemet prices |
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Dosage Form(s) Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Catapres, Catapres-TTS, Clonidine ER, Duraclon, Kapvay, Nexiclon XR | Other carbidopa / levodopa brands include: Atamet, Dhivy, Duopa, Parcopa, Rytary | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
15 hours |
2.3 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 371 drugs are known to interact with clonidine:
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A total of 486 drugs are known to interact with Sinemet:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
September 03, 1974 |
May 02, 1975 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.