Comparing Amiodarone vs Sotalol

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Amiodarone	Sotalol	Enter another drug to compare

Amiodarone

Sotalol

Prescription only

Amiodarone should ONLY be used in the treatment of life-threatening ventricular arrhythmias that have not responded to other treatments. Amiodarone does not appear to increase life expectancy and can... View more

Prescription only

Prescribed for Atrial Fibrillation, Atrial Flutter, Ventricular Arrhythmia. Sotalol may also be used for purposes not listed in this medication guide.

More about Amiodarone

More about Sotalol

Ratings & Reviews

Amiodarone has an average rating of 4.9 out of 10 from a total of 95 ratings on Drugs.com. 39% of reviewers reported a positive effect, while 48% reported a negative effect.

Sotalol has an average rating of 6.5 out of 10 from a total of 56 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 25% reported a negative effect.

View all 95 reviews

View all 56 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Tiredness (14.7%)
Dizziness (10.5%)
Insomnia (10.5%)
Shortness of breath (10.5%)
Weakness (6.3%)
Constipation (5.3%)
Cough (5.3%)

View all Amiodarone side effects

Tiredness (16.1%)
Heart palpitations (7.1%)
Anxiety (5.4%)
Blurred vision (5.4%)
Chest pain (5.4%)
Depression (5.4%)
Dizziness (5.4%)

View all Sotalol side effects

Drug Class

Group III antiarrhythmics

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	100 each
Strength	200 mg
Per unit^*	$0.28 - $0.52
Cost^*	$27.86 - $52.44

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Quantity	50 each
Strength	80 mg
Per unit^*	$1.07
Cost^*	$53.73

View all Sotalol prices

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Dosage Forms

Intravenous solution
Oral tablet

Intravenous solution
Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

240 hours

12 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category D Positive evidence of risk

See the full pregnancy warnings document.

Category B No proven risk in humans

See the full pregnancy warnings document.

Drug Interactions

A total of 746 drugs are known to interact with Amiodarone:

279 major drug interactions (953 brand and generic names)
429 moderate drug interactions (1621 brand and generic names)
38 minor drug interactions (191 brand and generic names)

A total of 623 drugs are known to interact with Sotalol:

233 major drug interactions (795 brand and generic names)
359 moderate drug interactions (2836 brand and generic names)
31 minor drug interactions (300 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Amiodarone may be taken with or without food but should be taken at the same way each time. You... View more

Sotalol and alcohol may have additive effects in lowering your blood pressure. You may experience... View more

Disease Interactions

First Approval Date

December 24, 1985

N/A

WADA Class View classifications

N/A

P1 - Beta-Blockers

More Information

Patient Resources

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Amiodarone vs Sotalol

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