Comparing Alesse vs Seasonale

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Alesse (ethinyl estradiol / levonorgestrel)	Seasonale (ethinyl estradiol / levonorgestrel)	Enter another drug to compare

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Alesse (ethinyl estradiol / levonorgestrel)	Seasonale (ethinyl estradiol / levonorgestrel)	Enter another drug to compare
Prescription only Prescribed for Endometriosis, Abnormal Uterine Bleeding, Birth Control, Ovarian Cysts, Polycystic Ovary Syndrome, Gonadotropin Inhibition. Alesse may also be used for purposes not listed in this... View more	Prescription only Prescribed for Endometriosis, Abnormal Uterine Bleeding, Birth Control, Ovarian Cysts, Polycystic Ovary Syndrome, Gonadotropin Inhibition. Seasonale may also be used for purposes not listed in this... View more	Related suggestions Birth Control Mirena Nexplanon Lo Loestrin Fe Depo Provera NuvaRing Sprintec Abnormal Uterine Bleeding Medroxyprogesterone Norethindrone Provera Megestrol Sprintec Premarin Endometriosis Norethindrone Lupron Depot Orilissa Progesterone Medroxyprogesterone Zoladex Polycystic Ovary Syndrome Metformin Ethinyl estradiol / levonorgestrel Desogestrel / ethinyl estradiol Ethinyl estradiol / norethindrone Drospirenone / ethinyl estradiol Drospirenone / ethinyl estradiol / levomefolate calcium Popular comparisons Alesse vs Aviane
More about Alesse (ethinyl estradiol / levonorgestrel)	More about Seasonale (ethinyl estradiol / levonorgestrel)
Ratings & Reviews
Alesse has an average rating of 5.2 out of 10 from a total of 229 ratings on Drugs.com. 31% of reviewers reported a positive effect, while 39% reported a negative effect.	Seasonale has an average rating of 5.8 out of 10 from a total of 55 ratings on Drugs.com. 42% of reviewers reported a positive effect, while 33% reported a negative effect.
View all 229 reviews	View all 55 reviews
Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.
Acne (33.2%) Weight gain (21.8%) Mood swings (21.4%) Depression (20.5%) Nausea (20.1%) Cramps (17.0%) Anxiety (12.2%) View all Alesse side effects	Bleeding (41.8%) Cramps (30.9%) Spotting (29.1%) Weight gain (16.4%) Sexual dysfunction (12.7%) Acne (10.9%) Headaches (10.9%) View all Seasonale side effects
Drug Class
Contraceptives	Contraceptives
Generic Availability
Lower cost generic approved	Lower cost generic approved
Pricing and Coupons * Prices are without insurance
We could not find an exact match for this medicine. Try searching the Price Guide directly.	We could not find an exact match for this medicine. Try searching the Price Guide directly.
Get free Discount Card	Get free Discount Card

Dosage Forms
N/A	Oral tablet
Brand Names
Other ethinyl estradiol / levonorgestrel brands include: Afirmelle, Altavera, Amethia, Amethia Lo, Amethyst, Ashlyna, Aubra, Aubra EQ, Aviane, Ayuna, Balcoltra, Camrese, CamreseLo, Cerinta, Chateal, Chateal EQ, Daysee, Delyla, Dolishale, Elifemme, Enpresse, Falmina, Fayosim, Iclevia, Introvale, Jaimiess, Jolessa, Joyeaux, Kurvelo, Larissia, Lessina, Levlen, Levonest, Levora, Lillow, Lo Simpesse, LoJaimiess, LoSeasonique, Lutera, Marlissa, Minzoya, Myzilra, Orsythia, Portia, Quartette, Rivelsa, Rosyrah, Seasonale, Seasonique, Setlakin, Simpesse, Sronyx, Trivora, Twirla, Tyblume, Vienva View more	Other ethinyl estradiol / levonorgestrel brands include: Afirmelle, Altavera, Amethia, Amethia Lo, Amethyst, Ashlyna, Aubra, Aubra EQ, Aviane, Ayuna, Balcoltra, Camrese, CamreseLo, Cerinta, Chateal, Chateal EQ, Daysee, Delyla, Dolishale, Elifemme, Enpresse, Falmina, Fayosim, Iclevia, Introvale, Jaimiess, Jolessa, Joyeaux, Kurvelo, Larissia, Lessina, Levlen, Levonest, Levora, Lillow, Lo Simpesse, LoJaimiess, LoSeasonique, Lutera, Marlissa, Minzoya, Myzilra, Orsythia, Portia, Quartette, Rivelsa, Rosyrah, Seasonique, Setlakin, Simpesse, Sronyx, Trivora, Twirla, Tyblume, Vienva View more
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.
45 hours	45 hours
CSA Schedule ¹ View glossary of CSA terms
N Not a controlled drug Is not subject to the Controlled Substances Act.	N Not a controlled drug Is not subject to the Controlled Substances Act.
Pregnancy Category
X Category X Not for use in pregnancy See the full pregnancy warnings document.	X Category X Not for use in pregnancy See the full pregnancy warnings document.
Drug Interactions
A total of 501 drugs are known to interact with Alesse: 77 major drug interactions (199 brand and generic names) 374 moderate drug interactions (1405 brand and generic names) 50 minor drug interactions (620 brand and generic names)	A total of 501 drugs are known to interact with Seasonale: 77 major drug interactions (199 brand and generic names) 374 moderate drug interactions (1405 brand and generic names) 50 minor drug interactions (620 brand and generic names)
Alcohol/Food/Lifestyle Interactions
Grapefruit juice may increase the blood levels of certain medications such as levonorgestrel. You... View more	Grapefruit juice may increase the blood levels of certain medications such as levonorgestrel. You... View more
Disease Interactions
Smoking Abnormal genital bleeding Abnormal vaginal bleeding Carcinomas (estrogenic) Hypercalcemia in breast cancer Hypertension Thromboembolism/cardiovascular Hepatic neoplasms Breast malignancy Liver disease Angioedema Gallbladder disease Hypercalcemia Hyperlipidemia Liver disease Melasma Depression Fluid retention Glucose intolerance Retinal thrombosis Thyroid function tests Cardiovascular disease Hyperlipidemia Weight gain	Smoking Abnormal genital bleeding Abnormal vaginal bleeding Carcinomas (estrogenic) Hypercalcemia in breast cancer Hypertension Thromboembolism/cardiovascular Hepatic neoplasms Breast malignancy Liver disease Angioedema Gallbladder disease Hypercalcemia Hyperlipidemia Liver disease Melasma Depression Fluid retention Glucose intolerance Retinal thrombosis Thyroid function tests Cardiovascular disease Hyperlipidemia Weight gain
First Approval Date
March 27, 1997	September 05, 2003
WADA Class View classifications
N/A	N/A
More Information
Side effects Drug interactions Dosage Pregnancy warnings Drug images Support group	Side effects Drug interactions Dosage Pregnancy warnings Drug images Support group
Patient Resources
Alesse uses	Seasonale uses
Professional Resources
Prescribing information	Prescribing information
Related Treatment Guide
Endometriosis Abnormal Uterine Bleeding Birth Control Ovarian Cysts Polycystic Ovary Syndrome Gonadotropin Inhibition	Endometriosis Abnormal Uterine Bleeding Birth Control Ovarian Cysts Polycystic Ovary Syndrome Gonadotropin Inhibition

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

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Comparing Alesse vs Seasonale

See also:

Provera

Slynd

Botox

Yaz

Depo Provera

Nexplanon

Sprintec

Mirena

Lo Loestrin Fe

Levonorgestrel

Further information