Comparing Acyclovir vs Valtrex
| Acyclovir | Valtrex (valacyclovir) |
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| Acyclovir | Valtrex (valacyclovir) |
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Prescription only
Acyclovir is an antiviral drug that treats infections caused by HSV-1, HSV-2, and varicella-zoster viruses such as chickenpox, genital herpes, and shingles. It is most effective when started within... View more |
Prescription only
Prescribed for Cold Sores, Herpes Simplex - Suppression, Herpes Simplex - Mucocutaneous/Immunocompetent Host, Herpes Simplex - Mucocutaneous/Immunocompromised Host, Herpes Zoster, Ramsay Hunt... View more |
Related suggestions Cold Sores (Herpes Simplex Labialis)
Herpes Simplex, Suppression
Herpes Zoster
Herpes Simplex, Mucocutaneous/Immunocompetent Host
Popular comparisons
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| More about Acyclovir | More about Valtrex (valacyclovir) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Acyclovir has an average rating of 8.2 out of 10 from a total of 189 ratings on Drugs.com. 77% of reviewers reported a positive effect, while 11% reported a negative effect. |
Valtrex has an average rating of 8.6 out of 10 from a total of 303 ratings on Drugs.com. 82% of reviewers reported a positive effect, while 10% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Acyclovir side effects |
View all Valtrex side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Acyclovir prices |
View all Valtrex prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Sitavig, Zovirax |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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4 hours |
3.1 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 67 drugs are known to interact with Acyclovir:
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A total of 91 drugs are known to interact with Valtrex:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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January 25, 1985 |
June 23, 1995 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.