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Zoledronic acid and Body Aches: What Users Say (Page 2)

Brand names: Reclast, Zometa, Aclasta

Reviews for Zoledronic acid

Commonly mentioned side effects
  • kat...
  • Taken for less than 1 month
  • June 26, 2022

Zoledronic acid for Osteoporosis "This drug, Reclast, is hideous! The side effects included fevers of 103, horrible body aches, diarrhea, neck pain, bone pain, swelling, and pain of hands and feet. Ten days out from my infusion and I am still feeling miserable. 'Take 2 APAP and you will be fine,' said my MD; what a crock! Every patient should be told the significant risk for hideous side effects that last much longer than 48 hours."

1 / 10
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  • 54_...
  • Taken for less than 1 month
  • July 5, 2022

Zoledronic acid for Osteoporosis "After reading all of the really negative comments, I was very anxious. However, I'm a 54-year-old female diagnosed with the spine of an 80-year-old. I weighed the pros and cons of potentially having a really nasty flu-like several days vs. a potentially shortened and pain-filled, miserable life and decided that Reclast was worth it. I have arthritis in my knees, hips, spine, etc., so I was anticipating a nasty interaction, but that was not the case. I had my infusion at 9:30 on a Thursday morning and felt okay for most of the day. I woke up around 2:00 a.m. on Friday with aches, pains, and chills much like the flu, though the last time I got the flu, it was MUCH worse. I ran a low-grade fever for a few hours, but by Friday afternoon, I was able to go to the grocery store. I took off-brand arthritis-strength acetaminophen throughout and drank as much water as I could. I highly recommend Reclast if you're able to rationally weigh the pros and cons of being sick compared to BROKEN."

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • May 9, 2022

Zoledronic acid for Osteoporosis "I’m an active, fit 69-year-old woman. I still work full time and am a daily gym visitor. Neither Prolia nor Evenity worked. My doctor recommended Reclast. I was simply advised to drink extra water. My infusion was in the morning. The day was uneventful until later in the evening, I had side effects of chills, feverishness, and body aches. A rough night followed by a rough morning. I actually fainted and, thank goodness, didn’t hurt anything. Days of fatigue followed. Lots of Aleve. Weird symptoms like severe pain in both thumbs! Writing now difficult. A bit better each day, but highly doubtful I’d do it again."

3 / 10
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Frequently asked questions

  • Sha...
  • October 22, 2021

Zoledronic acid for Osteoporosis "I had my Reclast infusion on 10-19-21 and will say I was extremely nervous from all the negative reviews. However, my experience wasn’t bad at all. I’m on my 4th day after and feel great. I did, however, after 12 hours, develop fever, chills, body aches, headache, but they weren’t that bad. Very tolerable. The worst was the chills and severe night sweats on the second night. Felt a little tired and headache on the 3rd day, but great after. My Dexa scan was -2.4. I will get another bone density test and pray it’s improved. I will definitely do it again. Trust my doctors."

9 / 10
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  • Wil...
  • Taken for less than 1 month
  • March 8, 2022

Zoledronic acid for Osteoporosis "Had Reclast infusion last Thursday. I was fine during the day. I even rode my stationary bike the same night. But oh boy!! At 1:30 am, I woke up with chills and body aches like I had just done a marathon. I could not lift my left arm up, it was so painful. Every part of my body hurt, especially joints and areas that I have arthritis (osteoarthritis). I am at day 5, and the body, muscle, and joint pain are gone, but I have no energy, I am so tired, and I have this headache for 4 days that is bothersome. I called the infusion center, and the nurse stated headaches this far from the infusion date is not the norm to call my primary care doctor. Made an appointment. I would not tell anyone not to take this medication. Each person's reaction can be different. I believe that if this medication works as it is stated, I can deal with the temporary discomfort. But time will tell. All I know is I would rather have these symptoms that are not great than to have the pain of a fracture or, worse, be debilitated."

7 / 10
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  • Jil...
  • Taken for less than 1 month
  • July 31, 2022

Zoledronic acid for Osteoporosis "I was nervous to proceed with Reclast but happy to report my symptoms were mild and manageable. I’m 57 with a T score below -3, diagnosed about 9 months ago. Extra calcium, bone-building exercises with weights hadn’t decreased T score after 6 months. Needed additional intervention. Of options, Reclast seemed best. I hydrated well prior to the infusion and kept up with acetaminophen for about a week. The infusion was about an hour. The first 2 days had achiness in molars and jaws. Then had achiness on one side of my back, followed by more jaw pain and upper left arm achiness. None of this was too uncomfortable as I kept acetaminophen on board. A week after the injection, I had neck and head pain for about 5 days. On day 6, I had odd swelling in my right thumb joint. It receded, then left middle finger, then 2nd left toe, then ball of right foot swelled. This lasted only about 2-3 days. I am 2 months post now and okay. Hope it worked!"

7 / 10
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  • Anonymous
  • Taken for less than 1 month
  • August 29, 2021

For Osteoporosis "I was on Prolia shot for a couple of years and was great, but due to an insurance change they wouldn't approve it, so I was upset for the fact that they would rather put me through an IV infusion drug instead. Even though I asked many questions, I was told that the only complaints were achiness. OMG, I was fine 'til 2:30 am. I swear someone broke all my ribs on my right side. I couldn't breathe, move, then on day 2 still the same even with pain meds they ended up giving me, but now throwing up and nauseous, headache and stabbing joint pain. Today is day 3, still the ribs hurt but not as bad and still can't even touch them and waking up with being nauseous. I will never do/take this again ever."

2 / 10
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  • Ver...
  • Taken for less than 1 month
  • January 15, 2022

For Osteoporosis "I can honestly say that this has been one of the worst experiences of my life. I’m 54 and live with regular pain due to rheumatoid arthritis, but the pain caused by this drug was another level. I hydrated before the infusion at 9 am and continued afterwards, went back to my desk to work, and all was fine until around 4:30 pm when I was finishing up a meeting and I realized my lower back was hurting. By 9 pm I had severe chills and every part of my body ached. That first night, the pain was almost unbearable and I could only get to the bathroom by having my wife help me. I must have vomited around 40 times. It really was the night from hell. Day 2 was pretty grim, but my wife got anti-sickness pills and codeine from our family doctor, which helped a little. This is day 3 and I can move about now slowly but still feel like I’ve been run over by a truck which then reversed over me. I have no idea how long it’s going to take to recover fully. I will NOT have this drug again."

1 / 10
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  • Lee...
  • Taken for less than 1 month
  • May 15, 2025

"I’m 48, two years post breast cancer and bone density has already dropped 8.6% due to hormone suppressants. So oncologist recommended. Had 4 mg infusion. The infusion was fine. Took about 30 mins all up. Had it at 3 pm. Was perfectly fine until midnight when the pain hit, fevers, chills. Felt worse than the flu or when I had COVID twice. Body aches x 10. Headaches and rigors. Eye socket pain. Jaw pain. Was like that for 2 days, then very slowly started to settle. Pain was mostly in my ribs/torso and fingers for first 36 hrs, then moved to my hips and legs. Had cramping calves one night. Had shooting/stabbing pains across my ribs to lower back and hips. Have been taking paracetamol and codeine for pain pretty regularly and it still hurt a lot! Definitely kept my fluids up. Not eating much. Needed the week off work."

5 / 10
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  • Pop...
  • March 31, 2021

For Osteoporosis "My first infusion for osteoporosis was on a Monday. It went well, and I felt normal the rest of the day. I drank 5 glasses of water to remain hydrated. Tuesday morning I felt weak and tired, yet I still carried through the day. I walked 2 miles in the afternoon and another 2 miles in the evening. My feet felt achy, and my joints felt stiff all day. Every now and then, a quick shot of bone pain. I was exhausted by the evening and took a hot shower. I began feeling feverish, and my temp was 99.5, so I took 650 mg Tylenol and went to bed. I woke up at 3:30 am Wednesday, sweaty and used the restroom to void. I was feeling weak, nauseous, and faint. I have a history of vasovagal syncope and knew it was coming on. I laid flat on the floor supine. The episode passed, and I went back to bed. I woke up at 8:15 am and had another bout of nausea and feeling faint; again, laid flat on the floor, and it passed. Wednesday I felt tired and weak; yet continued to function."

6 / 10
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  • TKB...
  • October 18, 2016

Zoledronic acid for Osteolytic Bone Metastases of Solid Tumors "I have been taking Zometa for breast cancer with metastasis to the bones and have been on it for 8 months now, and I have only had minor aches and pains... no major complications from the drug."

10 / 10
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  • rob...
  • Taken for less than 1 month
  • January 22, 2015

Zoledronic acid for Osteolytic Bone Metastases of Solid Tumors "IV Zometa yesterday. Woke up this morning, body aches, headache, fever, slept all day."

2 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.