Reclast and Fatigue: What Users Say

• Anonymous
• June 29, 2020

For Osteoporosis "I had my first infusion of Reclast in early March 2020. Within a day, I was in the ER. I suffered greatly with nausea, vomiting, extreme bone pain, and fever. The fever, loss of appetite, fatigue, malaise, and other symptoms lasted for 21 days. My rheumatologist was beside herself with worry yet very helpful and compassionate. I could not eat more than toast and soup and kept a thermometer and Tylenol at bedside to treat the recurring fever. By the way, I tested negative twice for Covid-19 with a negative antibody test so coronavirus was excluded as the cause. Please do your research when deciding on an osteoporosis drug. I cannot rate the effectiveness until my next DEXA scan in 2021. But in the words of my doctor, 'never, ever again will you receive Reclast.'"

• Anonymous
• June 29, 2020

For Osteoporosis "I had my first infusion of Reclast in early March 2020. Within a day, I was in the ER. I suffered greatly with nausea, vomiting, extreme bone pain, and fever. The fever, loss of appetite, fatigue, malaise, and other symptoms lasted for 21 days. My rheumatologist was beside herself with worry yet very helpful and compassionate. I could not eat more than toast and soup and kept a thermometer and Tylenol at bedside to treat the recurring fever. By the way, I tested negative twice for Covid-19 with a negative antibody test so coronavirus was excluded as the cause. Please do your research when deciding on an osteoporosis drug. I cannot rate the effectiveness until my next DEXA scan in 2021. But in the words of my doctor, 'never, ever again will you receive Reclast.'"

• Lin...
• Taken for less than 1 month
• April 30, 2022

For Prevention of Osteoporosis "I had my infusion on a Wednesday afternoon. Woke up at 1:30 a.m. in the worst pain I've ever experienced. For the next 24 hours, I was in pain, especially my sternum and ribs. Fatigue was so severe I could not walk without support, even my teeth were painful. I was constantly nauseous. After 24 hours, the symptoms began to subside, but even 4 days later, I experienced fatigue. Was it worth it? Don't know yet. But wish I had been told what was possible rather than just some people 'may' experience some negative effects. My experience may not be the norm, but on the pain scale of 1-10, it was a 15. Do your research rather than taking the doctor's word. Know what you may experience."

• MAW...
• Taken for less than 1 month
• April 8, 2021

For Osteoporosis "I had a Reclast infusion 10 days ago. I had flu-like symptoms for two days and femur and pelvic pain one day. Thought I was past it. On day 8, I woke up with swelling in my hands, knees, and thighs. I cannot bend my leg to kneel with very bad pain. I’m 72 and very active. I easily do yoga, Pilates, and Qi Gong. Currently walking like a 90-year-old. I’m fatigued and in pain. It’s significantly interfering with my daily activities. Very fatigued. I drank water as instructed. Currently have a call into my rheumatologist."

• Cat...
• Taken for less than 1 month
• March 8, 2020

For Osteoporosis "I had my first Reclast infusion one week ago. The night before the infusion and for 3 nights after, I took loratadine (Claritin). The day of the infusion I drank a lot of water, took electrolytes, and 500 mg Tylenol. I asked that the infusion be given over 60 minutes rather than 30 minutes, and that was done. I had some fatigue and minor muscle aches for a few days afterwards, but no other side effects."

• Den...
• January 8, 2020

For Osteoporosis "I had my Reclast infusion about two months ago. The first week was fine, then it was downhill from there. I get chills, dizziness, a terrible cough to the point of almost choking. The fatigue is awful, I sleep 12-13 hours per day and don’t want to get out of bed. I have been to the doctor, and they have checked me for everything under the sun, including CT scans, and nothing is wrong with me. I will never do this again, and I sure hope these symptoms don’t last the entire year."

• Ire...
• June 24, 2022

For Prevention of Osteoporosis "I very nearly didn’t have my Reclast infusion because of sites like this that terrify people. I have very bad osteoporosis, and I need surgery on my back to hopefully stop my pain and enable me to walk without a walker. I listened to my doctor, read everything about Reclast (it does give you all information about possible side effects, including seeing your dentist prior to getting Reclast). I am on my 3rd day after my first infusion. I have felt heavy fatigue, a bit of aching in my body, some pain in various bones that goes away fairly quickly, a headache on top of my head that is controlled with Tylenol, and some brain fogginess. As my doctor and the nurse who administered my infusion (and told me I could leave if I was too nervous) said to me - hundreds of millions of people take this medication and are fine after feeling a bit rough for about 3 days. The ones who write about their problems are in the vast minority. To others who are scared, DON'T read these negative posts!!"

• Lun...
• November 22, 2019

For Prevention of Osteoporosis "On 11/13/2019, I had a Reclast infusion. Today is 11/22/2019. I have had body/bone pain, aches, malaise, fatigue, chills, and diarrhea since the infusion. Starting yesterday, I have severe lower abdominal cramps and I'm not eating. I am having an abdominal ultrasound next week. The effectiveness of this drug is NOT worth the pain and misery, and I won’t know for a year if it helps. #NEVER AGAIN! Think twice before you do it!"

• Lun...
• November 22, 2019

For Prevention of Osteoporosis "On 11/13/2019, I had a Reclast infusion. Today is 11/22/2019. I have had body/bone pain, aches, malaise, fatigue, chills, and diarrhea since the infusion. Starting yesterday, I have severe lower abdominal cramps and I'm not eating. I am having an abdominal ultrasound next week. The effectiveness of this drug is NOT worth the pain and misery, and I won’t know for a year if it helps. #NEVER AGAIN! Think twice before you do it!"

• Ant...
• Taken for 1 to 2 years
• August 30, 2017

For Osteoporosis "Last year's infusion brought four days of fever, made difficult because I can't take aspirin or other non-steroidal anti-inflammatories. After two weeks, I'm nostalgic for those symptoms. This time body temp has stayed in the 96.4 range (95.9 this a.m.), when it's usually 97.6-98.6, so I feel very cold-until I get a savage hot flash requiring me to mop myself off with a towel, at least once an hour. I also have muscle cramps waking me up several times a night (more than prior to treatment). I've been lightheaded and fatigued. I also have fibromyalgia, but these symptoms are different/more intense. The doc told me he can do nothing. I'm frantic because I need to work and find that almost impossible. Anyone else with a situation like mine?"

• jmo...
• Taken for less than 1 month
• May 18, 2023

For Prevention of Osteoporosis "Received the first dose of Reclast yesterday, and never again. I can tolerate the fever, chills, and even fatigue, but the severe muscle pain is nothing like I've ever experienced before. The flu, COVID, and COVID vaccine side effects are a walk in the park compared to the Reclast muscle pain. This was my first and last dose. I didn't tolerate oral Fosamax either, so I'm done with osteoporosis treatment."

• AMA...
• Taken for 6 months to 1 year
• January 1, 2020

For Osteoporosis "I had the Reclast infusion back in March 2019. I have experienced more bone pain than I did prior to the infusion. Still in pain. The day after I had the infusion I had to go to the ER due to higher than normal blood pressure. 196/102. A headache, etc. Is this normal to still be in pain and fatigued?"

• Man...
• July 17, 2020

For Osteoporosis "55-year-old with osteoporosis (genetic predisposition as well as early menopause). Had my first infusion yesterday. Did prep with lots of water and Tylenol (hence up peeing throughout the night). Today I am sore, stiff, have a headache, and fatigued. But all manageable with Tylenol and Advil (taken 2 hours apart). Deep breaths hurt and took an almost 3-hour nap today (at least during the pandemic I don’t have to work)."

• NoR...
• Taken for less than 1 month
• November 29, 2018

For Prevention of Osteoporosis "The 1st infusion of Reclast has left me feeling fatigued, with terrible pain and swelling in my hands, especially thumb joints, that is not improving after nearly two weeks, along with overall body aches and pains, headaches, and difficulty sleeping. I would never consider taking this drug again!"

• Con...
• Taken for less than 1 month
• February 17, 2020

For Osteoporosis "It has been 3 weeks today (Feb 17th) that I had my infusion, and I am still experiencing upper respiratory headache and some blurred vision, also fatigue in the afternoon. My appetite is starting to come back, but you’re right, some foods don’t taste the same. Still have the occasional pain in my legs, not as bad, hopefully getting better. I’ve started walking again, made it 2 miles today, so that’s a positive."

• Flu...
• Taken for less than 1 month
• June 23, 2024

For Osteoporosis "I am 58 with osteoporosis. Knowing my mother experienced severe gastro issues with Fosamax, my doctor recommended Reclast. I was not told to drink water prior, so I only had a small bottle of water with me. Within 6 hours, I had COVID-like symptoms with a 101.4 fever and very achy muscles and bones. I also had indigestion, and my chest felt like an elephant was on it. I took Advil every 4-6 hours, which helped. This lasted a good 50+ hours and then turned into fatigue for another 1-2 days. Hopefully, this will have been worth it."

• pas...
• Taken for 1 to 6 months
• July 8, 2022

For Prevention of Osteoporosis "I also had horrible pain from a Reclast infusion this year. I was in the ER and was going to be admitted, but the pain was finally relieved with steroids and many IV pain meds. My pain in my spine, ribs, and shoulders was unbearable. I had severe fatigue for many weeks. I continue to have pain in my upper back. Horrible drug!"

• rvt...
• Taken for less than 1 month
• August 16, 2022

For Prevention of Osteoporosis "On day 9 of my infusion, still having a headache every day. Now my severe neck pain is just awful, I can't move my neck. Zapped all my energy, hard to get moving every day. Never again will I take this treatment!!!!"

• Ver...
• Taken for less than 1 month
• June 8, 2023

For Osteoporosis "I am 54 years old, a breast cancer survivor, and Reclast knocked me on my butt. Had it Friday afternoon, and by the evening, I had a 103°F fever, chills, and the worst bone pain I have ever experienced. It is now Thursday of the following week, and I'm waking to swollen joints and can barely walk or get ready for work. The fatigue is insane. I'm praying this helps my bone density because I am second-guessing if I can do this again."

• Kat...
• Taken for 6 months to 1 year
• June 9, 2023

For Osteoporosis "It’s been 8 months since I had my first infusion and still have back and side pain, along with pain that radiates from my back and side to my groin area. After reading about side effects again, I’m wondering if this is related to Reclast? The back pain I expected, and it occurs 2-3 times a month and is somewhat difficult to even walk. I take Advil, and that works. I still have fatigue too."

• Lin...
• Taken for less than 1 month
• August 22, 2022

For Prevention of Osteoporosis "When suggesting Reclast, my APRN said I may feel flu-like for 3-4 days. She strongly encouraged adherence to keeping hydrated and using Tylenol. I had my infusion Friday afternoon with no issues. I continued hydrating and taking Tylenol every 6 hours as instructed. I was fine on Friday but began feeling fatigued Saturday morning. This got progressively worse during the day. I moved slowly and had difficulty staying awake. By night, I had body chills. I had some pain in the area of my bladder, and several of my teeth hurt. I took Tylenol before bed and woke on Sunday feeling better, no chills, no tooth pain. I still felt tired and had some bladder discomfort. I actually slept from 1 to 2:30 pm (I never sleep during the day). I woke up feeling better and even met a friend for dinner out. Today is Monday, and I am feeling pretty normal. Maybe the best thing to do is realize you are going to feel flu-like for a few days, plan to lay low, sleep as needed, hydrate, and take your Tylenol."

• Ros...
• Taken for less than 1 month
• April 5, 2022

For Osteoporosis "After receiving an infusion on Thursday, I was in the ER Friday with chest pain and rapid heartbeat. I got checked out and no problems were found, although I still have chest pain, rapid heartbeat, dizziness, fatigue, and headache after a week. I do not recommend anyone receiving this infusion. My insurance did not cover another medication used for bone density."

• Anonymous
• Taken for less than 1 month
• May 9, 2022

For Osteoporosis "I’m an active, fit 69-year-old woman. I still work full time and am a daily gym visitor. Neither Prolia nor Evenity worked. My doctor recommended Reclast. I was simply advised to drink extra water. My infusion was in the morning. The day was uneventful until later in the evening, I had side effects of chills, feverishness, and body aches. A rough night followed by a rough morning. I actually fainted and, thank goodness, didn’t hurt anything. Days of fatigue followed. Lots of Aleve. Weird symptoms like severe pain in both thumbs! Writing now difficult. A bit better each day, but highly doubtful I’d do it again."

• Ali...
• Taken for less than 1 month
• August 4, 2022

For Osteoporosis "66 y/o female with recent diagnosis of osteoporosis. Have had osteopenia for years but unable to take Fosamax, etc., due to reflux. Took first Reclast July 18. Everything was fine for the first 24 hours, then had chills, fatigue, nausea, achy muscles, headache, and dizziness. All symptoms resolved in 3 days except dizziness, which continued for almost 2 weeks. The flu-like symptoms were bearable, but the prolonged dizziness scared me. I still get dizzy if I turn my head a certain way and have to sleep sitting up. I hope it helps my bones, but I don’t think I will take this drug again."