Zepbound User Reviews & Ratings (Page 2)

• PRe...
• Taken for less than 1 month
• February 12, 2025

For Weight Loss (Obesity/Overweight) "On week number three, I started with stomach cramps and diarrhea. The night before, I had a huge helping of Boom Chicka Pop kettle corn. While the packaging states it only uses cane sugar, I came to the conclusion that this product (perhaps in the amount eaten) suddenly didn’t agree with me while taking Zepbound. I’ve lost 5 lbs in 2 1/2 weeks. Diarrhea and cramping subsided after 36 hours."

• Lis...
• Taken for 1 to 6 months
• April 19, 2025

For Weight Loss (Obesity/Overweight) "48 years old female started 2.5 mg one month ago and experienced very little, if any, side effects. I lost 10 lbs, started at 274. Just took my first dose of 5.0 on Thursday and initially felt fine but started to struggle with diarrhea that just won't stop. Will see if it's unrelated or not and adjust accordingly. This medication also immediately got rid of my swollen feet, and so far it has not returned. That alone is worth the cost."

• Joa...
• Taken for less than 1 month
• November 10, 2024

For Weight Loss (Obesity/Overweight) "I'm a 64-year-old woman. 5'2" and weighed 177. I've lost 10 pounds in my first 3 weeks. With the heartburn, I had to force myself to eat last night when I wasn't really hungry. I think I ate the scrambled eggs too late in the evening. I had horrible diarrhea and vomiting. That was the first time that happened. I'm hoping it's just because I ate so late on such an empty stomach. I have had no desire to eat the first 3 or 4 days after injection. I have to remind myself to eat something."

• Pau...
• April 23, 2024

For Weight Loss (Obesity/Overweight) "I am a 72-year-old female, 5'7", and 204 lbs. I started Zepbound 3 weeks ago. I don't have the nausea, diarrhea, and other ailments that I've read about, but I've had a problem with itching. From the top of my thighs, up my back and my front and my arms all itch a lot. My doctor told me to quit the injections for 3 weeks to see if it helped. For the first time, I didn't do what he recommended because at this point, I've lost 7 lbs and I'm very happy about that. Hopefully the itching will die down with time. I'm very optimistic about my success and I will continue. It's only costing me $245 a month which is very doable. Taking Benadryl and using cortisone cream seems to help."

• agm...
• Taken for 1 to 6 months
• December 18, 2024

For Weight Loss (Obesity/Overweight) "I have been on Zepbound for 16 weeks. I have lost 23 lb. I am a 6'3" 74-year-old man. I wanted a kick start to get to my goal, which I am at. Except for three weeks at 5 mg, I have been on 2.5 and am now after a brief go at 5 mg. My experience has been generally acceptable, but nausea and fatigue are a real challenge. No vomiting or diarrhea. I have had some acid reflux. The key has been to eat good clean food and stay away from fried or greasy. I have reduced my alcohol intake, but they are empty calories, and why do it? It just makes it tougher. The reason I drink some is usually social, but I have found it easier to abstain than I expected. Here's the deal: I think people lose weight on these drugs because they don't want to get sick and choose to behave and stay at a calorie deficit, and bingo, the math kicks in. It's not rocket science. I have taken a week off while on an overseas trip. Again, I didn't want to get sick. I am about to take another week off."

• Xer...
• Taken for 1 to 6 months
• May 18, 2025

For Weight Loss (Obesity/Overweight) "Began taking on January 12, 2025. Moved up dosage monthly under supervision of Physician’s Assistant from 2.5 mg to 10 mg. No noticeable side effects. Lost 30 lbs between start date and May 18, 2025 (from 268 to 238 lbs). Previously tried Ozempic and Wegovy each for about two weeks each. Had horrible side effects (explosive diarrhea and vomiting) bad enough to discontinue. Was apprehensive about Zepbound — but experience was completely different. Only exception was May 17-18, when consumed about three glasses of wine (previously had no alcohol during usage period). Had explosive diarrhea just like when using Ozempic and Wegovy. Tested for COVID on May 18, but result was negative. Intend to continue with Zepbound (despite the predatory cost — over $500/month out of pocket but with some insurance). Intend to avoid alcohol consumption and see whether side effects diminish. Pleased with Zepbound results thus far."

• Ama...
• Taken for 1 to 2 years
• March 19, 2025

For Weight Loss (Obesity/Overweight) "I have lost nearly 80 lbs over the past 20 months. My A1c has improved greatly, as has my sleep apnea. My weight has remained stable at 152 lbs over the past 6 months, and I am able to resume skiing and hiking! I can keep up with my peers again! I have made major life changes with my diet/eating and resuming regular exercise, and I look forward to maintaining a healthier lifestyle for the rest of my life! I experienced uncomfortable diarrhea, gas, and unpleasant burping initially, which resolved. I also experienced hair thinning, but not severe. I now have a somewhat flattened butt, which I have read is known as Ozempic or Zepbound butt, and am working on weight training exercises to rebuild muscle in my legs, glutes, and arms. I would not recommend this drug to anyone who is not able or willing to put in the hard work of developing lifestyle changes and including exercise and diet, due to the muscle loss factor."

• Mk6...
• Taken for 1 to 6 months
• March 10, 2025

For Weight Loss (Obesity/Overweight) "I started in January 2025 with the 2.5 dose. For the first two weeks, I experienced nausea and diarrhea off and on. For the last two weeks, I was fine. I am on my second week of 5 mg. The first week, I was so sick - I take the shot late Friday afternoon - I was in bed most of the day on Saturday with nausea and fatigue. I did vomit once. Sunday was the same. The rest of the week, I felt fine. Second shot last Friday - I was okay on Saturday - able to function but very nauseous. Woke up on Sunday and spent most of the day in bed due to nausea and fatigue. The anti-nausea medicine helps but not so much for me. Today I am functioning with some nausea. The benefits of this drug are obvious. I don't eat as much as I did before the medicine. I've lost 16 lbs so far. The nausea bothers me. I should be able to function and not get sick every weekend after a shot. I no longer have diarrhea - I am constipated instead. When I take Miralax, I cannot think about it or I get sick."

• Aut...
• Taken for 6 months to 1 year
• March 3, 2025

For Weight Loss (Obesity/Overweight) "I am 45 years old and female. I have been on Zepbound for eight months. I started at 275 lbs and am now at 235 lbs. The day after I first took it, my stomach was so full it hurt, just from my normal portion sizes. Over time, the dosage has increased to 7.5. I am a little more tired than usual, but that's a small price to pay. The vast majority of side effects occur when I overeat. There's no way to know which of these I will have then: pain in my stomach, egg burps, loud flatulence, and/or diarrhea. I have been sick a lot more than usual, along with swollen lymph nodes and hoarseness, but there's no way to know if they're related or not."

• Anonymous
• Taken for 6 months to 1 year
• March 4, 2025

For Weight Loss (Obesity/Overweight) "It was rough in the beginning, with diarrhea, then constipation and heavy belching. The diarrhea ended after about a month, but constipation has continued. In addition to those symptoms, I experienced an undercurrent of nausea for several months, with it being more pronounced just after eating. After about eight months, the nausea abated for the most part. I started on the 2.5 and moved up in dosage every 2 months or so. I am entering month 10 and am on the 12.5 dosage. For the first 6-7 months, I lost approximately 1.5 lbs/wk, and over the last 2-3 months that has slowed down a little. I have lost a total of 50 lbs. The other side effect I've experienced is I sometimes have low blood sugar in the mornings, so I will have juice or something to help take care of it. It is easy to use, and despite the rough start, I am pleased with the results."

• Lor...
• Taken for 1 to 6 months
• July 16, 2025

For Weight Loss (Obesity/Overweight) "I started on Zepbound 3 months ago. I began at 2.5 mg the first month and then went to 5 mg for 2 months. I had no side effects whatsoever. I started 7.5 mg last Sunday, and by Tuesday, I was nauseous, vomiting, and had diarrhea. It went away overnight, and now I’m fine, but not sure I want to continue with 7.5 mg due to the side effects. I have lost only 10 lbs in the 3 months I have been on it, but will have to stop taking it if these side effects continue."

• Ano...
• Taken for 1 to 6 months
• May 29, 2025

For Obstructive Sleep Apnea/Hypopnea Syndrome "Dosage 2.5. Effective for sleep apnea and weight loss. Having side effects including queasiness, lightheadedness, diarrhea, constipation, Vitamin B12 blood test elevated to 1270. Starting weight 156. Now 147 after 7 doses."

• kin...
• Taken for 1 to 6 months
• May 19, 2025

For Obstructive Sleep Apnea/Hypopnea Syndrome "Caused diarrhea, fatigue, kidney problems on lowest dosage for 4 months."

• DeN...
• Taken for 1 to 6 months
• October 29, 2024

For Weight Loss (Obesity/Overweight) "BMs are diarrhea daily, but only once or twice a day, so it's controllable. Losing weight, truly zero appetite, and when I eat, I feel full very quickly. No headaches or increased heart rate for me."

• Oti...
• Taken for less than 1 month
• April 20, 2025

For Weight Loss (Obesity/Overweight) "Lost 5 lbs the first week. Lots of diarrhea. Feeling fatigue fairly often. Rarely feel hungry. Easy to go most of the day without eating."

• Ano...
• Taken for less than 1 month
• May 27, 2025

For Weight Loss (Obesity/Overweight) "Just got started, currently in my 3rd week. Moderate to severe diarrhea started after the 3rd shot. No nausea at this point. Some stomach pain."