Zepbound and Burping: What Users Say

• Xer...
• Taken for 1 to 6 months
• May 21, 2025

For Weight Loss (Obesity/Overweight) "Second review. I'm male, 75 years old. Began taking 2.5 mg on January 12, 2025. Today is May 21, 2025. Weight dropped from 268 to 232.5 (35.5 lbs). Went to 10 mg on May 8. Took 2 weekly 10.0 doses in that time period. Suddenly, explosive diarrhea, sulfur burps, nausea, and fatigue began May 18. My PA has advised not taking my 10.0 injection tomorrow (my regular day). Think I may need to drop back to 7.5 — had no side effects at that level (or at 2.5 or 5.0). Had already decided not to go to 12.5 because I have a friend who was fine on 10.0 but encountered major side effects at 12.5. Still, even 10.0 may not be right for me. The weight loss is stunning; haven't been at this level in over five years — but for a BMI of 25, I still have over 70 lbs to go, so I don't want to abandon Zepbound altogether. It may take longer to get there, but that's fine if it means I can avoid side effects."

• Krg...
• Taken for less than 1 month
• February 4, 2025

"Follow Up: I am currently on day 11 of Zepbound 2.5 mg. As of this morning, I have lost 11.73 lbs. Daily, I documented how I felt and symptoms. The first 24 hours of injection #1, I had extreme fatigue, normal appetite, and a whole lot of belching. Day 2, belching, less hungry, no other symptoms. Day 3, I had no appetite, no other symptoms. Day 4, less than normal appetite, no other symptoms . Days 3 and 4 have just been repetitive. I have had no negative side effects, BUT I also have made sure to eat high-protein foods for every meal, even on the days I had no appetite, nothing greasy (thinking about it turns my stomach), no high-sugar foods. As of today, I’d say; if you work with the medication, the medication will work with you. Update you in a couple of weeks."

• Pro...
• Taken for 6 months to 1 year
• February 25, 2025

For Weight Loss (Obesity/Overweight) "I’ve been on Zepbound since 8/1/24 (305 lbs, 5’6). So far, I lost 65 lbs, I’m 45 lbs away from my goal. My current dose is 10 mg. I experience side effects within 24 hours of injection administration, ranging from nausea, vomiting, belching, diarrhea, abdominal pain, fatigue, and dizziness. The side effects last about 24-36 hours. The medication definitely decreases my appetite and cravings. My doctor stopped my BP medication as I continue losing weight and my BP readings are good. My husband has noticed that I stopped snoring, lol. My plan is to reach my weight goal and stop the medication. I have changed my relationship with food. I look at food more as fuel for my body instead of indulging and overeating. I also introduced portion control and exercise, mostly walking and swimming. My insurance covers the medication."