Zepbound for Weight Loss (Obesity/Overweight) User Reviews (Page 5)

• Tam...
• Taken for 6 months to 1 year
• June 23, 2025

"My life has changed at 61 years old. I no longer have knee pain associated with a knee replacement. I no longer have arm issues from my rotator cuff surgery. I am currently doing the job of a 20-year-old and doing it better than most! God bless Zepbound."

• Ene...
• Taken for less than 1 month
• April 7, 2025

"Well, I am beyond the moon now that I have been approved by my insurance to take Zepbound! I have been trying to lose weight for years, practically killing myself with diets and exercise that just didn't work for my body type. I am a 59-year-young lady weighing in at 188.6 lbs. I am looking forward to my much-needed and wanted weight loss experience with Zepbound! I did my homework... Now let's go!"

• KCP...
• Taken for 1 to 6 months
• August 30, 2024

"Life-changing. Down 30 pounds in 5 months. Within a few hours of the first dose, I experienced hunger suppression, increased satiety, and best of all, reduced food noise. I thought about food 24/7 before taking this medication. Despite tracking calories and eating whole foods and eliminating most sugar, I always craved sweet and high-fat foods like ice cream and felt hungry even after a meal. On this medication, I crave veggies and fruit and protein. Side effects: as a woman going through menopause, the hot flashes have been miserable. I also have always had an extreme heat intolerance for hot weather. On this medication, hot flashes are gone and I've enjoyed summer for the first time in my life. Negative side effect: constipation. Easily manageable with Miralax and Benefiber."

• Mar...
• Taken for 1 to 6 months
• May 25, 2024

"Started using Zepbound in March 2024, at 2.5 mg. History of Obesity (BMI > 29) and Hypertension. Starting weight was 202 lb. and Blood Pressure Avg. of 153/90. As of today, May 24, 2024, currently on 10mg. My weight is currently 177 lb, having lost 25 lbs (12%) of starting weight. It was easy to learn how to use the injection pen, and it is a painless process. I am also exercising, running 4-5 days per week and weight training 2 days per week. Exercise is an important adjunct to weight loss treatment, and can help maintain muscle mass while losing weight. It is also imperative to eat foods rich in protein and green, leafy vegetables. Side effects have been minimal, with occasional constipation, which is remedied by using Miralax or similar products."

• Kat...
• Taken for 6 months to 1 year
• July 11, 2024

"Zepbound (tirzepatide) is amazing - if you are not losing much on semaglutide, see if your doctor will let you try tirzepatide. I’ve been on Zepbound seven months and I’m down 55 pounds. Took 2.5mg the first month and then spent 5 months on 5mg. Just moved up to 7.5mg this month and it has totally killed my appetite. Main side effect for me is fatigue, especially the day of the shot and the next couple of days. I plan to stay on 7.5 until I reach my goal weight and then go on maintenance. I will have to keep taking it - otherwise it is likely I will gain all the weight back. Yes, it is expensive but worth it."

• Rev...
• Taken for 1 to 6 months
• April 6, 2024

"I have been taking Zepbound for about 3 months now and have lost 18 lbs. The experience has been mostly unpleasant. The gastric issues that accompany the medication are almost unbearable. The desire to eat did not go away, and I mostly did not eat because I was always so nauseated and experiencing acid reflux. Every day has been miserable. It did make you feel good but not in a satisfied way, just full like you ate way too much to the point of feeling sick. It feels great to have lost 18 lbs, but I will probably not continue the shots due to the gastric issues."

• MDM...
• Taken for 1 to 6 months
• December 31, 2024

"Started this in October of 24, went to 5.0 mg. In November, 7.5 for two weeks in December, then dropped back to 5.0 because of a few side effects, but mostly because I lost 25 lbs. in 2.5 months. That put me about where I want to be. I've stayed steady on my weight for 3 weeks now, taking 5.0 mg. every 10 days. It's great, I've had to buy new pants that fit and feel much better. Side effects weren't too bad, but you'll definitely know it if you eat too much, and over time (a couple of months) your body will slowly get used to it. I don't crave foods as I used to and only eat what I need, which is smaller amounts. I wasn't too overweight, but at 57 I suffered from high blood pressure, and age kept my weight slowly creeping up and harder and harder to keep under control. This works great!!!"

• Jus...
• Taken for less than 1 month
• December 28, 2024

"After my second 2.5 shot, the side effect symptoms are too much for me to handle. I’ve barely kept any food down except for a day and a half before my second shot. I can’t find a way to prevent acute nausea, and the vomiting is now making me weak. I knew there would be side effects, but for me, this medication doesn’t work for my body. I chose to discontinue the medication and will work with my doctor to see what other options may work for me. I have been unable to participate in family and home life, feeling trapped between being so sick I can’t leave my bed and spending a lot of time vomiting or feeling like I will if I try to move or drink water. I hoped this would be the tool to help me on a healthier path, and it’s not the right one for me, but I can see how it would possibly help others if they aren’t affected by side effects."

• Gre...
• Taken for 1 to 6 months
• May 7, 2025

"I've been on Zepbound for 3 months. I have lost a total of 56.4 lbs. I have learned from friends I work with and other people's testimonies that use Zepbound that most people that don't lose weight don't want to try to change their eating habits, like giving up sugar. Even my doctor that's on it has struggles with this, lol. Zepbound is an awesome friend, a tool that helps with the fight, but you also have to be willing to make lifestyle changes too, and if you do, you'll see bigger results. Giving up sugar is the best thing that I have done for myself, I don't even crave it anymore and feel better than I ever have."

• Bob...
• Taken for 6 months to 1 year
• February 23, 2025

"I’ve been taking Zepbound for 9 months and have lost approximately 25% of my original body weight, 267 lbs down to 200 lbs. I’m a 76-year-old white male with peripheral neuropathy. One noticeable side effect that I have experienced is loss of taste, which makes it hard to enjoy food. I have reached my original goal. Another benefit I have experienced is that I can sleep without using my CPAP."

• Dia...
• Taken for less than 1 month
• June 5, 2025

"I have been so sick on Zepbound. Nonstop diarrhea weeks 2 and 3. Ended up in urgent care for IV hydration and labs. Doc took me off it after a severe reaction. It's been 2 weeks off it and I'm still suffering from diarrhea. Very weak and light-headed. Weight loss was fast. I started healthy and am now sick every day. Weight loss is not worth my overall health."

• Jun...
• Taken for 6 months to 1 year
• January 26, 2025

"I am on the lowest dose and have been on it for several months and have lost 24 lbs. I started off slowly walking 0.5 mile a day for the first week until I was able to do 3 miles a day. I had a friend walk with me, which was a good support. The last month, I have gained 3 lbs. back because of the weather, but I am back on my grind again. So far, no real side effects. When I first started, I felt a little queasy the first 24 hours."

• Anonymous
• Taken for less than 1 month
• March 27, 2025

"I had my first injection 4 days ago. I weighed in at 215. I have already seen a significant change in my desire to eat. I don't even consider eating until late afternoon now, while before, all I could think about was food and snacks. I work at a desk 8 hrs a day and have little opportunity to move. I also work in the medical field and have done extensive research. I am not one to try the latest trend or take medications. I had reservations about this journey, but I just felt like I needed to pop in and say I feel great with no side effects thus far, my mind feels better, and I have already lost some weight. I was educated by my Dr that I would not see immediate results, but I have!! He asked me to be patient with it, and I thought that this drug didn't sound promising. Others may not have experienced this, but I have!"

• LML...
• Taken for 1 to 6 months
• January 21, 2025

"5’1”, 180 lbs, 63 yrs. old female, BMI 34%. History of cardiac disease and hypothyroidism. I’ve been taking the 2.5 mg dose for six months with virtually no worrisome side effects. I do experience unusual tiredness within 8–12 hours of each dose. Who doesn’t enjoy a good nap, yeah? I'm currently experiencing moderate hair loss, which is a concern. I consulted my PCP, who agreed we should rule out other potential causes such as a recent change in thyroid medication, nutrient deficiencies, or age before deciding the next step in my weight-loss journey with Zepbound. My current weight is 142 lbs. That’s 38 lbs (an approximate 1.5 lbs/week or 6 lbs/month) weight loss over six months. It’s just the boost I needed. According to the CDC, losing 1–2 lbs per week is a healthy weight loss goal. It’s reassuring to know that my weight loss is at a healthy pace at the lowest effective dose of Tirzepatide. Thank you, Eli Lilly, for the Zepbound coupon card ($25 co-pay)."

• Fin...
• Taken for 6 months to 1 year
• September 3, 2024

"I started Zepbound in March of this year, along with regular exercise and a more balanced diet. Since then, I have lost 65 lbs. For the first time in over 20 years, I am under 200 lbs. I feel great. I barely use my inhaler, my knees rarely hurt, and I can jog! My labs are all within normal limits, and I feel so much better about myself. I have very little side effects from ZB: nausea the day after I take it, intolerance to most alcoholic beverages, and I get hot after every meal. I’ll take those side effects any day if it means that I’ll continue to have my life back. I’m on the highest dose now and will continue until I reach my goal of 165. I’m 5’4'' and 44 yrs old. I’m not sure that I want to get back to my high school weight of 140 or less. Anyway, I’m not here to steer anyone, I just wanted to share how well it’s going for myself."

• My...
• Taken for 1 to 6 months
• April 22, 2024

"Since starting Zepbound 13 weeks ago to shed 60 pounds, I've gradually increased from 2.5 mg to 10 mg. It's effective, but sleepless nights have become my unwelcome companions, especially on the higher doses. Heartburn and that uncomfortable chest sensation are no picnic either. Despite dropping 30 pounds, I feel drained—fatigue, dizziness, and concentration issues plague me. To tackle these side effects, I'll either stick to 10 mg or drop to 7.5 mg. But with a $1,000 monthly price tag and the hassle of hunting down my prescription, quitting Zepbound crosses my mind. Yet, the thought of returning to the weight loss battle isn't enticing either. Swapping out heavy meals for light options like chicken and soups helps ease discomfort, but what I really crave is a solid night's sleep. I'm giving it one last shot, tweaking my diet and powering through my remaining doses before deciding—is it worth it?"

• Wis...
• Taken for 6 months to 1 year
• February 8, 2025

"I started on Zepbound on May 24. To date, I lost 36 pounds. I have 10 more to go, but I am going to have to stop taking it. Right from the first shot I took, I had right eye pain on and off. Now with the higher doses of 10, 12.5, and 15 mg, it is happening more, and I also break out in a rash/hives at the injection site, starting with dose 10 mg. I tried Benadryl 30 minutes before the shot and icing that site for 10 minutes after the injection, but that does not help. That area will itch for 3 days and leave a red mark on my skin. I used to be on Wegovy and never had that issue, but did have more stomach/diarrhea with Wegovy. Zepbound is the better one, but unfortunately, I can't take it."

• Mat...
• Taken for 6 months to 1 year
• March 18, 2025

"Question: Why wouldn’t you use this to get a head start on a new life? I started on Monjaro for weight loss and had to switch to Zepbound after three months (insurance). I always dieted and would stall after 20 pounds. My ultimate goal was to lose enough weight to safely run again. After a year, I had lost 80 lbs and was able to start running. I just finished a half marathon, one year after starting this journey. The side effects of it are what is advertised; some nausea, it can hit you but goes away quickly, the heartburn was less with Zepbound than Monjaro, and the decrease in using the bathroom is a godsend for anyone experiencing IBS. The injection is not bad with the auto pen. Take the leap and change your life!"

• Anonymous
• Taken for 1 to 6 months
• July 19, 2024

"16 weeks now on Zepbound. I am down 27 lbs. 5’5’ 170 lbs now 143 lbs. Had high cholesterol. This is a great product but you have to be ready to eat healthy too. Protein shake in the am. Protein bar in the afternoon. Try Fuffil bars. Walmart sells them, they are amazing. Salads, salmon, pork, chicken, veggies for dinner. Try Sobol, they have a great green smoothie and healthy fruit options. Kodiak products are good too. No side effects, but I chose to stay at 5 mg. No need to go up. I have so much energy now, work out 6 days a week. It’s a new me, and I’m loving it."

• Cin...
• Taken for 1 to 6 months
• August 10, 2024

"I didn’t have any side effects. I lost 15 lbs in 4 months. I lost 6 inches from my waist. I went from 37 inches to 31 inches. I’m starting to tone up. I’m back to working out 4-5 days for an hour a day. I still have ways to go, but it’s looking good and I’m feeling good."

• Ano...
• Taken for 1 to 6 months
• July 13, 2025

"I’ve been on Zepbound for almost 4 months and down 34 lbs. The only side effect I’ve experienced is the rash/itching at the injection site. I’m thankful that I’ve had no other side effects, and although it’s annoying, I’m still excited that I’m continuing to lose. It definitely curbs my appetite, and logging what I eat in an app is also very helpful! I’m hoping as my dose continues to increase gradually that I will continue to lose weight since I would like to lose 100 lbs more!"

• Eli...
• Taken for 1 to 6 months
• December 30, 2024

"I started Zepbound at 2.5. My weight was 249 and I'm 5'2''. I've lost 34 lbs starting in July. I went up to 7.5 and was doing great. Then the third dose, all the side effects started in spades. I started vomiting, no appetite, tired all the time. I drink water all the time (and I'm a reformed soda drinker). I'm suddenly itchy all the time. The weight loss has slowed down. But I'm not giving up in order to get my knee replacement. This comment section makes me feel like I'm not alone. Thanks for listening. Oh, the one thing that could make me quit is the price is ridiculous! I'm running out of money."

• Rom...
• Taken for 1 to 6 months
• December 3, 2024

"56 yr female, 257 lbs (20 years post gastric bypass). Started Zepbound 11/3 2.5 mg. Lost 12 lbs in the first 4 weeks. Minimal side effects until week 3-4. Felt dizzy, headaches, lethargic though likely due to not enough calories. 1st 5 mg dose yesterday and feel great so far. Absolutely no food noise or cravings since the 1st shot. No issues at all with the injection site or pain. Will stay at 5 mg as long as I can before increasing. This medication has been a life changer for me. I was hesitant due to reported side effects as I researched for over a year before I decided to move forward. My insurance denied, I appealed and got the decision overturned. Meds currently covered at 100%, thankfully. I am exercising though I have always walked. I am not a big eater to start with, the difference is I no longer crave foods. I eat because I have to, so I make better food choices. Looking forward to continuing on the path I am currently on."

• Bab...
• Taken for less than 1 month
• October 8, 2024

"I started Zepbound 3 weeks ago, and I have to say I feel remarkably well and really am enjoying how it has decreased my appetite and kept me on track with my high-protein and low-carb diet. I am losing 2.7 pounds a week and am also using MyNet Diary to track my intake. My BP has dropped 12-15 points, and the swelling in my legs is gone. I’m using 5 mg weekly and haven’t had side effects. First time in years I’ve felt so well. I’m psyched that I can finally reach my goals."

• Bec...
• Taken for 1 to 6 months
• August 11, 2024

"I have lost over 35 lbs in 5 months. I started at the 2.5 and have worked up to the 10. Zepbound is incredibly effective at assisting with the weight loss. Greasy fatty foods definitely upset my stomach now. The first day post-shot, I am super tired and have a very mildly upset stomach, after that, it’s fine. I am freezing all the time, so for sure take a jacket wherever you go! I am not starving and do not have cravings at all. Staying hydrated seems to help with curbing the initial side effects. Initially, I found myself hardly eating just because I wasn’t hungry. I had to make a concerted effort to make myself sit down and eat. Protein and veggies made me feel a ton better and didn’t result in any digestive discomfort. It really was a trial and error. Alcohol is not your friend, even 1 or 2 drinks makes me feel awful. I ended up naturally having a cleaner diet and drinking a lot more water just to minimize the digestive side effects."