Zepbound for Weight Loss (Obesity/Overweight) User Reviews (Page 4)

• dil...
• Taken for 1 to 6 months
• March 10, 2025

"I have been taking Zepbound for 4 weeks. I have lost 20 pounds. I am not hungry, no side effects, more energy, and I sleep so much better. I am on 2.5. I love this drug. I did not want to believe the good reviews or the bad ones, I just needed to know for myself, and now I do. It is great. Take a chance, you will see it really works."

• mis...
• Taken for 1 to 6 months
• January 23, 2025

"I have had a good experience with Zepbound. So far, I have lost 30 lbs in 6 months. This is my take and experience. You will feel sick if you eat improperly. You're not going to lose weight and continue to eat like you have been. Butter, fat, oil, and overeating will make you feel nauseous. These drugs slow down your digestion. I learned that in the first 24 hrs. I was at a barbecue and piled the food on my plate like normal. I felt sick the rest of the day. I learned my lesson. Make sure you drink plenty of fluids. Since digestion is slower, other functions slow down too! (If you know what I mean). Don't starve yourself, that will make you feel sick too. I have found that avoiding too many carbs and eating high in protein is working for me. I'm hoping my brain is rewired for when I go off Zepbound. I don't plan on being on this forever."

• On...
• Taken for less than 1 month
• February 18, 2025

"With the initial injection of 2.5 taken before bed. I woke up with painful, swollen neck lymph nodes and extreme fatigue. The next day, the swollen lymph nodes seemed to have moved down, now in the chest/armpit area. On the 3rd day, one of my knees is swollen and horribly painful. I have absolutely never had any knee issues prior to the injection. If I get nauseous, drinking more water helps. At this start of the med, continuing is definitely not worth it."

• Bor...
• Taken for 1 to 6 months
• January 17, 2025

"I’m almost 46. I have been struggling with weight loss all my life, joined food addiction programs, and tried other diets, and nothing worked. I lost some but gained it right back. I started at 220, but in numbers, I was not diabetic, so my insurance wouldn’t cover weight loss medication. My doctor worked with me for months and kept trying until it was finally approved. I did manage to get down to 186 pounds before starting on Zepbound. I have lost an additional 22 lb in 2.5 months! I’m at 164 now, and I haven’t been here in years. I can relate to many of the comments here. I don’t think about food, no cravings. I feel satisfied. I have been doing one meal a day, and I feel great. I don’t feel anxious, deprived, or hungry. I don’t worry about what I’m going to eat next. I don’t catch myself always snacking. It’s changed my brain in a way that I’m at peace. Just started on a 7.5 gm, and I did have some nausea just the very first day, but no other side effects."

• Nan...
• Taken for 1 to 6 months
• July 26, 2025

"I have had great success with Zepbound! I am down almost 40 pounds in 3 months. I started at 201 lbs. I have been lucky not to have any issues or side effects. I do work at it. I drink lots of water and walk 20 minutes twice a day."

• Dav...
• Taken for 1 to 6 months
• September 17, 2024

"I started at the beginning of May 2024 at a weight of 236. My doctor recently retired, and I was seeing his PA, and he started me on Zepbound 2.5 for a month. I had lost several pounds and moved to 5.0 mg, which I am still on, today is September 17. The PA and I agreed that this dose seems to be working well for me - today, I am 186 pounds! This medication is amazing! I have had no side effects at all."

• Tri...
• Taken for 1 to 6 months
• September 3, 2025

"I have been on Zepbound for a month now, lowest dosage of 2.5 mg, and today I'm to start my second month with the next dosage up, but personally, I'm done. I've lost 7 pounds this August 2025, and though it may not seem like a lot to most people, it's quite something to those of us who have a very hard time losing weight. The thing is, how can a person be happy with the weight loss when you're miserable all the time? My first week went well, but come the second, the stomach aches/cramps and nausea are too much... every day, all day, through the night... sicker than a dog. I've heard good things about Zepbound, but the side effects are just too much for anyone to feel good about the journey it takes you on, and if the side effects only get worse with the higher dosages, then I might as well not eat at all for what little I can now, when I can. I'm 300+ pounds, and this was my last hope for any type of weight loss help. I don't recommend this product, the side effects outweigh any of the happy."

• Ano...
• Taken for 1 to 6 months
• August 15, 2025

"I was on Wegovy for a few months starting last year. I had GI issues going on and ended up getting off Wegovy in January of this year. I had gallbladder removal surgery in March. Issues went away. I consulted with my GI doctor to see if I could get back on Wegovy. He said I should be fine. Went to my PCP and asked about getting back on Wegovy. She recommended Zepbound as “side effects are less.” I’ve been on Zepbound for 3 months now. Lowest dose. After the second day of injection, I get the worst sulfur burps and diarrhea. Once I have a sulfur burp, the diarrhea is inevitable. It’s gotten to the point where it wakes me up in the middle of the night and I have to use the bathroom. This just started happening within the last month. It usually lasts about a day. Never had these issues with Wegovy. In fact, Wegovy worked much quicker with me as far as losing weight. Didn’t have these burps and diarrhea when I took it for months."

• Tpo...
• Taken for 1 to 6 months
• March 3, 2024

"50-year-old female with 100 lbs to lose and PCOS. Been on Zepbound for 6 weeks (just took 7th shot). Minimal side effects. Occasional nausea, headaches, and sore muscles, usually the day after injection, but they go away by the next day. Taking the 5 mg dose right now. I have been getting large injection site rashes with itching, burning, and swelling with the last 3 doses. The swelling and itching go down after 3-4 days, but the red spots are still visible from all 3 of the previous doses. I didn't get this with the 2.5mg dose at all. Hoping it was just this last box of the medicine and the next will be better. I have only lost 5 lbs in the 6 weeks I have been on it, which has been very disappointing. It has lowered my blood pressure though. It was on the high side of normal before, now it's perfect. Really hoping that going up to the 7.5mg dose will start having better results for me as I have got a long way to go, and hopefully the skin reactions won't get worse."

• And...
• Taken for 1 to 6 months
• June 8, 2024

"Started out great. Moved to 5.0 and had AWFUL vomiting on day 3 after injection. Dr. tried to move me back to 2.5 but Rx store was unable to get it. Went 5 weeks before it was restocked. Started 2.5 again with 0 effect. And I mean zero. Moved to 5.0 and the nausea is there, but so far, no vomiting. What concerns me is that I have suddenly been struggling with an elevated pulse and higher than normal BP. Wasn't an issue before, so not sure if it's related or incidental. May stop it because I just don't feel good. In addition over the 5 months of on and off again, I am down 4 pounds...and following a reasonable diet plan. Discouraged."

• Vio...
• Taken for less than 1 month
• May 30, 2024

"I started Zepbound about a week ago. Only had 1 injection, but for me personally, as soon as I did the injection, I immediately began to feel nauseated and dizzy for a good couple of hours, but then it subsided. I did have some anxiety about the side effects, and sometimes when I do have anxiety, I will feel nauseous and dizzy as well, so I really can’t tell if that was from the injection or anxiety. Either way, it stopped. Since then, I barely eat. I NEVER feel hungry at all, and when I do, I eat hardly a handful of something before I feel full and stop eating. I don’t know if that’s normal. I’m supposed to get 60 grams of protein a day. I drink 2 of those 30 grams of the Premier protein shakes, not my favorite, but it will do, and that keeps me feeling full for pretty much the ENTIRE day. I don’t snack at all anymore. Again, I’ve only had 1 injection but have noticed some immediate changes."

• Ano...
• Taken for 1 to 6 months
• June 11, 2025

"As soon as I began at the 2.5 dosage, I modified my diet radically to mitigate or even entirely avoid the dreaded side effects of indigestion, nausea, constipation, heartburn, and vomiting. I also embarked on a free-weight program to build muscle. Fortunately, I’ve experienced none of the unpleasant side effects. I’ve titrated up after each 4-week dosage and am now in the middle of 7.5 mg. My doctor tells me I have lost more weight than most patients have at this point. I also have chronic inflammation, which extra weight exacerbates, and I’m watching carefully to see that marker decrease. That’s the good news. Zepbound has completely changed my relationship to food. I consider myself a “foodie.” That’s now behind me. I remind myself that it’s been only 10 weeks. I’m hopeful that at some point, I will be able to enjoy more of the foods that were once such a large part of my life."

• Daw...
• Taken for less than 1 month
• March 18, 2024

"Started Zepbound 2.5 mg just 3 days ago. For the first time in my LIFE, I am eating to nourish my body, and not to satisfy hunger or cravings! Super excited to see how the weight will drop with new habits. Downside, I wasted a pen the very first time I injected because I didn't remove the grey closure. My fault for not thoroughly following the instructions but total bummer because the cost of this med is not cheap and the pharmacy says they can't fill an Rx for just one pen. It would be nice if the manufacturer of the drug would allow a single pen to be purchased for a lesser cost."

• Nan...
• Taken for less than 1 month
• January 30, 2025

"I have just started on the 2.5 mg dose. This is the end of my second week. I’m not experiencing any side effects except belching. I’m really looking forward to my weight loss and feel confident that with some walking daily and use of light weights I will reach my goal. I’m not overdoing the exercise, as when I do, I regrettably always quit. I’m paying for this out of pocket, so this is also a great motivator for me (get my money’s worth!) Using the injection is no problem, and I’m also looking forward to no more snoring (sleep apnea), which is a bonus as I didn’t know about that until I started taking it. This will please my husband! I’m purchasing it through Eli Lilly and my dr. sends them my script, I pay them monthly, and they send it to me via mail. I’m hoping Medicare may cover this in the future, as it’s been in the news it will if you have sleep apnea."

• BK...
• Taken for 1 to 6 months
• April 5, 2025

"I started this journey at 387 lbs. On the initial dosage of 2.5 mg, I lost 12 lbs in the first month. I have no side effects to speak of, and the food noise is 90% gone - although it seems to know when I'm within 24 hours of my next injection. The weight loss from the 5 mg cycle feels like another 10 lbs, but my Dr. visit will tell the tale. I am VERY happy with this decision, and I have NO regrets."

• NJ-...
• Taken for 1 to 6 months
• January 23, 2025

"I've finished my 5th month of Zepbound injections. The dose pen makes the injection simple and painless. It took me a few weeks to actually feel that this was changing my appetite or cravings, but once it did, I have no problem resisting the habitual munching. Although my diet changes have helped the amount of food I eat at one time, I don't get the full feeling that a lot of people talk about. So I have to know when to push away from the servings. This was prescribed for weight loss, but I do have sleep apnea as well. I've lost 20 lbs, which matches the estimated 1 lb per week under this med. My goal weight is a 40 lb reduction. The only side effects that I've noticed are primarily increased gas and constipation if I don't push the fluids. So far, it's been a positive experience and I look forward to added results."

• Mer...
• Taken for 1 to 6 months
• November 5, 2024

"I started this medication in August 2024, and I have lost 35 lbs as of the beginning of November. I am very satisfied with this medication. I have rheumatoid arthritis, and being able to lose this weight has definitely helped my joint pain. I have tried other medications along with diet and exercise, and none have been as successful as Zepbound. I have been lucky that I have not had any side effects with this medication. I only have 15 more lbs to go. I would recommend this medication to anyone that has had trouble losing weight with other regimens."

• D R...
• Taken for 1 to 6 months
• March 14, 2025

"It definitely curbs your appetite, however, it destroyed my stomach. After 5 weeks, I couldn’t tolerate it anymore. I’m disappointed that my stomach and vomiting were so severe that it was not worth the risk. In a 3-week period, I had to go to the emergency room twice. I hope others have a better experience than I did."

• Ano...
• Taken for less than 1 month
• January 16, 2025

"I started 2.5 on 1/12/25. I haven't had any side effects. What I have noticed is the reduction in my need to snack. I was always wanting something after dinner. One snack turned into 2 or 3. I don't feel that way anymore. Sometimes I feel that I don't want to eat what's in front of me at mealtimes, but I am trying very hard to eat and keep protein up. I lift heavy weights 4 days a week, and I want to retain muscle if this ends up helping me finally lose the weight I've been burdened with for my entire life. I did get a bruise at the injection site. I can't wait to weigh myself to see if I've lost. So far, feeling great!"

• Kat...
• Taken for less than 1 month
• January 26, 2025

"I am so happy with Zepbound! I have lost 20 pounds in 3 months after 25 years of trying every diet, gimmick, supplement known to man, and nothing worked except this! My frustration and disappointment come from the insurance company that won't pay for it. I have been paying out of pocket, I get vials and do my own injections to save money. Now I need to go up in dose, and my new insurance turned me down even though I meet all the criteria. I did an appeal, and they came up with another reason to turn me down. I'm on my second appeal, and it's not looking good, so I guess I just have to blow up to 300 lbs and get diabetes and have a heart attack, which all runs in my family, before they will have to pay for it. The system is rigged! I have not had any side effects or problems with this medication."

• ric...
• Taken for less than 1 month
• May 26, 2024

"So, I took one dose, unfortunately, my doctor screwed up and started me at 15mg. I've been in the ED for 36 hours and have had the worst 3 weeks of my life. This is not a review but a caution, check your script thoroughly, make sure you're taking the right dose. I need to purge this dose from my system and then start a 2.5mg dose."

• Jus...
• Taken for less than 1 month
• December 28, 2024

"After my second 2.5 shot, the side effect symptoms are too much for me to handle. I’ve barely kept any food down except for a day and a half before my second shot. I can’t find a way to prevent acute nausea, and the vomiting is now making me weak. I knew there would be side effects, but for me, this medication doesn’t work for my body. I chose to discontinue the medication and will work with my doctor to see what other options may work for me. I have been unable to participate in family and home life, feeling trapped between being so sick I can’t leave my bed and spending a lot of time vomiting or feeling like I will if I try to move or drink water. I hoped this would be the tool to help me on a healthier path, and it’s not the right one for me, but I can see how it would possibly help others if they aren’t affected by side effects."

• Ani...
• Taken for 1 to 6 months
• August 15, 2024

"I am 72 years old, starting weight of 210 on June 13, 2024. 1 month of 2.5 mg, then been on 5 mg. Absolutely no side effects. August 14, 2024, down to 189. Never hungry. Was concerned this was slow weight loss with reviews of 20 in one month. These reviews were reassuring to me."

• Sus...
• Taken for 1 to 6 months
• October 19, 2024

"Been taking Zepbound 2.5 mg for four weeks - just had my fifth injection last night. Started at 254 lbs. and have lost 18 lbs!! My last weigh-in was 236 lbs.! The only annoying side effect I had was mild constipation. I had no idea what food noise was until it was gone. Wow. Finally understand what it is to be normal. Not sure what my goal weight will be yet, somewhere between 175-150 lbs. I'm in my early 50s and finally confident I'll have sustainable weight loss."

• cli...
• Taken for 1 to 6 months
• July 31, 2024

"I asked my doctor about starting Wegovy since my efforts weren't working, but she recommended Zepbound - and I am so glad she did! My appetite is no longer controlling me, and yet those pre-diabetic low blood sugar drops are gone. After 3 months at the 5 mg dose, I'm still consistently losing about 1% of my weight each week. The only side effects are minor constipation and heartburn, but they encourage me to drink more water. I was hesitant to start because...needles...but it's so tiny I don't feel it at all. I wish I had started sooner!"