Mounjaro and Stomach Pain: What Users Say (Page 2)

• Ano...
• Taken for 6 months to 1 year
• March 29, 2025

For Type 2 Diabetes "Been on Mounjaro since April 24. Started on 5 mg because I was on Trulicity, which gave me severe stomach pains. Was on 10 mg before weight loss started. I’m 5’0, lost 46 lbs, and A1C is 5.8. I now take 7.5 mg to avoid more weight loss. Hoping this will be my maintenance dose. Had very mild side effects initially, now just a little constipated, but coffee cures that. Feel better about myself. Very happy. Wish this came out years ago. Been diabetic since 42. Was unable to control both for a long time. Now I’m 68, and Mounjaro has made a believer out of me. I tell everyone about it that will listen. It affects everyone differently, so don’t always listen to the naysayers. Try for yourself."

• kee...
• Taken for 1 to 2 years
• April 18, 2025

For Type 2 Diabetes "I've been on Rybelsus, Trulicity, and Ozempic with minimal results both on A1C and weight loss, and lots of stomach issues. Presently on Mounjaro 10 mg for the past year, having gradually increased dosage along the way. Side effects are constipation, and approximately every three weeks I'll have an episode of stomach pain, sulfur burps, and vomiting. It's usually in the middle of the night, throwing up dinner and anything else eaten that day, sitting on my stomach all day. Vomiting, severe sweating, chills. After that, it passes, and I feel perfectly fine until weeks later it happens again. I can tolerate this side effect, and A1C is much better."

• Loi...
• Taken for 1 to 6 months
• April 24, 2023

For Type 2 Diabetes "I have been taking Mounjaro since December 2022, beginning with the lowest dose of 2.5 mg, and increasing to 5 mg, briefly going to 7.5 mg, and currently back at 5 mg. Anyway, I had already made huge changes to my diet and reduced my insulin, but couldn’t quite get my glucose levels where I wanted them. For the most part, it’s been great. I’m now off all other diabetic medication, including insulin, and am able to keep my blood sugars within range. I have some issues with constipation and definitely need to use a little help to keep things moving. Occasionally, I have a headache for several hours after injecting. I have gotten a little bit of a sour stomach after some meals, but not bad. I have lost a little weight, not a lot, but I’m not in a hurry to lose. I think I’d probably lose more at a higher dose. My last HbA1c was 5.3, and I would like to get it lower. I had more stomach trouble at the higher dose. I'm glad that I’m on it. An injection once a week is better than daily."

• mot...
• Taken for 6 months to 1 year
• March 17, 2023

For Type 2 Diabetes "I had to start at 2.5 mg due to always having issues with new medications and stomach trouble. I tolerated that well and then moved to 5.0 mg. Hunger came on around four weeks into the medication, so I started taking 5 mg twice a week. Lost around 15 pounds during the next 5 months, then the hunger came back on. Just now started 5 mg three times a week. Will see. Not pleased with my weight loss but am happy with my blood sugar levels."

• pat...
• Taken for 1 to 6 months
• May 23, 2024

For Type 2 Diabetes "I used this for the first month at 2.5mg and did fine. Didn't really notice too much change and minimal impact on my sugar numbers. After 1 month, my doctor increased the dosage to 10mg. From that point, day 1 after my shot, I experience complete loss of appetite, chills, gastric pain. Days 2-4, I just had the loss of appetite and gastric pain, soft stools. Day 5 after my shot, loss of appetite, pain & diarrhea. The 6th day, some appetite back, less pain, no BM at all. Day of next injection was good, was able to eat more, no pain, normal BM. Day after 2nd shot at 10mg, is repeating again. I was losing some weight at the lower dosage but the sugar numbers weren't that much improved. On the higher dosage, I'm no longer losing weight but my sugars are more in line and coming down."

• Jam...
• Taken for less than 1 month
• April 30, 2025

For Type 2 Diabetes "I only took 3 doses at 2.5 mg. By the time I took the 2nd shot, I was having trouble with my stomach hurting and starting to itch. After the 3rd shot, I broke out with a rash on my back, arms, and stomach. I decided not to take the 4th shot and contacted my doctor. During my visit, they decided for me to come off of Mounjaro. I was given a steroid shot, oral medication, and an ointment for the rash. My stomach still bothers me some but seems to be getting better. This has been 4 weeks today, and the rash hasn’t gone away completely yet. When in direct sunlight, it seems to aggravate or excite the rash. I don’t know if Mounjaro has any effects on moodiness, but while I was taking it, I was in a really good mood. I would have moments of intense bliss. After I stopped using Mounjaro, I’ve had moments of moodiness. This is getting better, but I thought it’s worth mentioning."

• Jea...
• Taken for 6 months to 1 year
• May 6, 2025

For Type 2 Diabetes "Have been on the 2.5 mg for almost a year. Do not want to increase dosage. Doctor is fine with that as well. I have lost about 70 lbs. since beginning this medication. My A1C is absolutely fantastic! Better than it has ever been. My weight is the lowest it's ever been. I was actually getting concerned with the weight loss and/or possible bad nutrition. However, my last labs were all fine! I've always concentrated on protein intake. I had gastric bypass back in 2006. Weighed 312 back then, am currently at 115. But do not look sickly or undernourished. I did have a recent ER visit for severe stomach pain. No other symptoms at all. They advised that I had ileus. So have several questions for the doctor at the follow-up visit this week. Have been type 2 for many, many years. Overall happy with the Mounjaro. Do have stomach pain at times, but it is manageable."

• Tip...
• Taken for 1 to 6 months
• December 8, 2024

For Type 2 Diabetes "Try taking Benadryl 45 min before injection, and take/inject at night. I do this and don’t get the stomach pain or nausea."

• Orl...
• Taken for 1 to 6 months
• September 9, 2024

For Weight Loss (Obesity/Overweight) "Lost 60 pounds in 4 months. Stomach pain and alternating diarrhea and constipation."

• Joh...
• December 12, 2024

For Type 2 Diabetes "I am having severe stomach pain, and last week I had two swollen lymph nodes on my neck, but they have dissipated over the course of a week. I am on the highest dose of Mounjaro."

• Jea...
• Taken for 1 to 6 months
• April 9, 2023

For Weight Loss (Obesity/Overweight) "I have had some mild stomach pain and mild constipation. I am not eating as much. I have some blurred vision, but not sure if it is related to the medication."

• Lin...
• Taken for 1 to 6 months
• November 24, 2024

For Type 2 Diabetes "Better than Ozempic, which caused severe stomach pain even in low doses, and so far not the same side effects with Mounjaro."

• Rod...
• Taken for 1 to 6 months
• May 11, 2025

For Type 2 Diabetes "Too many side effects when first taken, stomach pain, awful burps, fatigue, and body aches last 2-3 days. Need to be careful to eat small plain meals to survive."

• Dan...
• Taken for 1 to 6 months
• April 27, 2023

For Type 2 Diabetes "I am experiencing stomach pain and constipation. I have had a weight loss of 10 lbs in 6 months. Insurance suddenly decided to not pay for it when I needed the next 2.5 mg increase in dosage."

• Ano...
• Taken for 1 to 6 months
• June 16, 2025

For Type 2 Diabetes "Stomach pain and diarrhea. Severe indigestion, lots of burping and gas. My mouth stays dry."

• Ano...
• Taken for 1 to 2 years
• May 21, 2025

For Type 2 Diabetes "Effective, had some nausea/vomiting and stomach pain the first couple of months, but then resolved. Have lost over 40 pounds over 18 months and A1C is 5.3. Very satisfied."