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Nucynta User Reviews & Ratings (Page 5)

Nucynta has an average rating of 6.3 out of 10 from a total of 279 reviews on Drugs.com. 53% of reviewers reported a positive experience, while 28% reported a negative experience.

Reviews for Nucynta

Commonly mentioned side effects
  • har...
  • December 8, 2009

For Pain "My doctor put me on Nucynta for lower back pain because I told him tabs are taking over my life and too addictive. He said try this medicine and see if you like it. It's less addictive. It takes care of the pain for about one hour but makes me sleepy so I can't take them at work. Tablets made me not only work more comfortable but feel good too. So if you want to try it just remember it's not like Lortabs or Percocets."

6 / 10
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  • Anonymous
  • July 23, 2010

For Pain "I have been taking Nucynta for about 1 1/2 years now for fibromyalgia pain in my back. I started on the low dose of 50 mg, and that worked for a while, but had to move up to 75 mg. I think I may have to move up to the next mg dose again, but that does not mean that the medication is not working. Over the years, my fibromyalgia has slowly gotten worse, and I was not on any pain medicines for it because I did not know what was wrong with me. The only side effect I have experienced (besides the drowsiness for the first 2 weeks of taking the medicine) is being itchy. This is a medication that needs to be given the chance of at least 6 weeks before you decide that it isn't working."

9 / 10
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54 Report
  • she...
  • November 12, 2010

For Pain "I was just taken off Vicodin and given Nucynta to try for my chronic pain. I have chronic, acute pancreatitis and a kidney blockage. It was hard to find a pharmacy that carried this medication. I ended up going to a hospital pharmacy to have my prescription filled. The medicine is comparable to the Vicodin. I still itch with Nucynta, but not as bad as with the Vicodin. Nucynta's pain-relieving effects are short-lived. They last for about 3 hours. They change my voice also. I sound like a frog when talking. I am having trouble sleeping. This is only day 3 of taking this medication, so I will have to keep comparing. The medication does give me energy. It makes me groggy after about 45 minutes of taking the medicine."

7 / 10
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56 Report
  • YYC...
  • May 1, 2017

For Pain "These pills are a blessing! I started with 50 mg ER twice a day, then increased to 2 x 50 mg twice a day. Three days ago, it was increased again to 150 mg ER twice a day and 75 mg for breakthrough pain. I think the ER dosage will get increased once more to reduce the amount of the 75s I'm taking throughout the day as I've had to take them every 6 hours. I have quite a few side effects: hot flashes, sweating, incredibly itchy, very shaky, decreased appetite, nausea, and today for the first time, vomiting. BUT, I'm about 80% pain-free, and to me, that's a win. I'll take the side effects (maybe not so much the vomiting), especially the decreased appetite LOL. I have tried Dilaudid, naproxen, Percocet, and a couple others that I can't remember the names."

9 / 10
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32 Report
  • TN ...
  • Taken for less than 1 month
  • July 23, 2016

For Pain "After 10 years of a combination of treatments that included fentanyl 100 mcg every 72 hrs and dilaudid 2 mg 4x prn daily with injections, facet, and nerve block. I was diagnosed with MS in early 2014 on top of a major back injury and a decade of chronic pain. I moved to a different state and was taken off these meds without taper, so I not only went through withdrawal but was sent into an MS relapse. I was put on Nucynta and was experiencing major headaches, disorientation, flushing, dizziness, and more. After my husband thought maybe my blood pressure was elevated, I took my blood pressure and discovered it was dangerously low, 75/35! When between doses, my readings were normal at 110/72, but no more than 15 minutes after it dropped again!"

1 / 10
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  • Anonymous
  • March 4, 2010

For Pain "I have had this medicine for a week now. I am not totally sure if I like it or not. I cannot sleep if I take one of these pills. They make me feel like I'm on high doses of steroids. They do help with pain from rheumatoid arthritis. If you do not have trouble sleeping, then I think this medicine could work for you. If you are already suffering from sleep problems, then I would not advise this medicine."

5 / 10
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  • sla...
  • Taken for 6 months to 1 year
  • April 15, 2016

For Pain "Was put on this by my PD for around-the-clock pain relief. At first, it seemed to work fine with minimal sides. The ER that I was on definitely didn't last anywhere close to what the company claims in their literature. Could feel it wearing off after just 3 hrs. Sides were minimal, but the hot feeling that some have mentioned here started becoming very annoying, and that was only with the 100's. Mentioned this to my PD, and all she did was put me on a higher dose - something tells me she must be getting huge kickbacks from Janssen, the mfr."

6 / 10
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  • Pat...
  • Taken for 2 to 5 years
  • June 17, 2019

For Pain "I take one to two 50 mg a day in conjunction with Tramadol. Tramadol during the day and the Nucynta in the evening. The Nucynta really knocks out my joint and back pain with few side effects. Yes, it does cost a bit as there is no generic, but this has been a real help. Until I was put on this regimen, I was taking way too many ibuprofen all day long."

9 / 10
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29 Report
  • RBr...
  • Taken for 1 to 6 months
  • January 16, 2017

For Pain "I have severe back pain and have been prescribed Norco 10 mg 6x a day for almost two years. I moved and got in with a new doctor. She prefers a conservative approach since I am young and there is a risk for addiction with opiates. I am on Nucynta 100 mg IR, and it works great. There really is no change in the way it helps with pain or makes me feel from the Norco. I like the Nucynta better personally. Only con is that it is expensive, and insurance does not want to cover it."

8 / 10
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  • Jam...
  • January 4, 2017

For Pain "Was put on Nucynta 100 mg every six hours for a two week trial after 60 mg of morphine long-term use and tolerance. I have had major hot flashes, headaches, nausea. At first, I thought maybe the conversation wasn't done correctly, but this medicine just flat out does not work for me at all. I woke up with night sweats, had to go to the bathroom and couldn't go. I'd rather go back on the morphine and adjust the dosage up. They can have this drug."

1 / 10
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38 Report
  • Ace...
  • Taken for 1 to 6 months
  • August 16, 2019

For Pain "I take Nucynta in conjunction with Norco for neuralgia caused by a severe case of shingles (post-herpetic nerve pain). While my pain management doctor is trying blocks on the nerves, they have yet to be successful. The combination of Nucynta and Norco is giving me the temporary relief to get me through until I can find success from a longer-term solution."

7 / 10
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27 Report
  • Rac...
  • April 11, 2017

For Pain "I was prescribed this pill for pain after a surgery, and it did absolutely nothing. After my first dose, I had a grand mal seizure, and I was then diagnosed with epilepsy. This pill brought out the epilepsy in me that I never knew I had. DO NOT TAKE THIS PILL."

1 / 10
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39 Report
  • Twe...
  • Taken for 2 to 5 years
  • November 3, 2016

For Pain "I have a form of muscular dystrophy and take this for my chronic severe pain. I've been on the immediate release, 2x 50 mg a day. It is a miracle for me. I can function way better than I could on Norco or Oxy, and it works way better for managing my pain than lesser painkillers like Ultram. I've tried both the ER and IR and found the ER to not be as effective for me. Nucynta IR has seriously given me more quality of life. The only downside for me is there is not yet a generic available and it's extremely expensive (even with insurance)."

10 / 10
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  • sp ...
  • Taken for 2 to 5 years
  • June 16, 2016

For Pain "Run from it. I've been taking it for four years. The more you take, the more you have to have. It's synthetic and very addictive. 100 mg tab equals 40 mg morphine. I was taking six per day. It dulls the pain, but it dulls your mind too. I'm off it now, and I feel alive, and most of my back pain is starting to subside. I take Mobic, and I'm great. When I got hurt, it actually helped, but I built up a tolerance to it over four years. I've got five discs messed up."

5 / 10
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  • ram...
  • November 7, 2009

For Pain "My experience with Nucynta was very disappointing. Did not relieve pain any more than a few ibuprofen. And it made me feel tired, sleepy. I have been on many pain medicines in the quest to find something that allows me to function. This one will be at the bottom of my list, mainly due to its poor performance for me in easing the pain, combined with sleepy, tired, and a little dizzy."

1 / 10
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  • Lad...
  • Taken for 6 months to 1 year
  • August 24, 2016

For Pain "I have been on so many hydrocodone and oxycodone strengths and combinations that have given me, on a scale of 0 to 10, a 3 at best. I have degenerative disc disease, bulging discs, and hip/SI joint pain from ankylosing spondylitis. I don't take it every day, but as I need to. That should say something right there! I take the 50 mg, up to 2 times a day. It didn't make me sick to my stomach either. I will add one caveat - I have not gotten any migraine relief, which is what it was originally prescribed for."

7 / 10
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  • SBL...
  • April 23, 2011

For Pain "I have had chronic pain for 9 years following 2 brain surgeries and 2 spinal surgeries. Nucynta has been a miracle medicine for me. It allowed me to stop Fentanyl at high dosages for 3 years. It took a little time to adjust, but now I am thrilled. It is definitely worth the try, and I have tried every strong narcotic made."

10 / 10
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44 Report
  • MrP...
  • September 15, 2014

For Pain "They had me on this combination of 100's & 150's at different times in the day. Sometimes I would take my meds just fine; other times I would take them, my head would feel like it was going to explode, the white part on computer screens would dance around, giving me wicked vertigo. I don't know why it only worked for me on a pick and choose kind of bases."

7 / 10
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  • rag...
  • Taken for less than 1 month
  • December 22, 2017

For Pain "I have chronic pain from a defective knee implant, which is scheduled to be revised in a few months. The pain was successfully managed with Opana ER/IR. Because the FDA forced the manufacturer to remove Opana from the market, my pain management doctor switched me to Nucynta 200 mg twice daily. Within a few days, I started to experience severe side effects - constipation, nausea, stomach pain, headache, confusion, lightheadedness, inability to think clearly, joint and muscle pain, restlessness, insomnia. And the pain was only about 50% controlled. After 5 days, my doctor switched me to the fentanyl patch. Within a few days, all of the side effects went away, and my pain is much better controlled. In my opinion, Nucynta is a terrible drug."

1 / 10
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  • Anonymous
  • July 26, 2012

For Pain "On Norco-10 for 4 years - C4-C5 herniated disc. I went from 3/day to 4 or 5 a day as my tolerance built. 18-20 months ago, my doctor suggested Nucynta 100 3x a day. The max pain relief was just as good as the Norco-10, but I told the doctor that I wanted to go back to Norco because the Nucynta would 'crash' me between doses - fell off VERY quickly the last couple of hours. Got to two months ago. My doctor sends me to a PM specialist because he's not happy with all the acetaminophen. She puts me on tramadol and tells me to slowly back off the Norco. First, tramadol didn't work for pain, 2nd it nauseated me BADLY. I told her my history with Nucynta and she put me on 150 mg ER 2x/day. All GOOD 3 weeks later BUT with 1 or 2 Norco as supplements for breakthrough pain."

8 / 10
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  • Kur...
  • Taken for 1 to 6 months
  • June 24, 2016

For Pain "I took 150 mg x 2 daily of Nucynta for full-body stabbing pain, and it didn't even help one bit for the pain. I do not recommend this drug to anyone, it is a waste of time, money, and it doesn't work for moderate to severe pain. There was a survey on Facebook the other day in a support group, and Nucynta helped only 1 in 10 people for their pain. The only positive side is it had no side effects for me, but I would rather it had made me sleepy and helped my pain than waste my time and money. Disgrace of a pill."

1 / 10
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  • roo...
  • January 5, 2018

For Pain "I have herniated discs along with numerous other pain-related problems due to roofing for over 20 years and having a few nasty falls. I have been on Nucynta 100 mg IR for over 6 years, and there isn't any drug out there that compares to it. I have used Norco, Percocet, Roxy, and fentanyl patches. Only the fentanyl 25 mcg patches had any effect on the pain I've been in. Surgery will cost $14,000 after insurance pays $9,000.00, so I guess I go to stay medicated for another year to save."

8 / 10
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  • DWA...
  • Taken for 10 years or more
  • January 25, 2021

For Pain "I have been on Nucynta ER 250 mg 2x/day for several years. This medication is a lifesaver for me because it works for my pain and none of the side effects associated with other narcotics. I still have Oxycodone 10 mg for breakthrough pain management but only use as necessary. Nucynta provides relief in several different ways, and due to my genetics, it works great for me, where some will receive absolutely no relief. I do not suffer from tiredness, sleepiness, or any intestinal issues. My only issue is sometimes there are supply chain issues - the drug is manufactured in PR, and after major hurricanes, there have been disruptions. Also, pharmacists are very reluctant to fill even a day early, so it is difficult to plan your life around picking up a prescription. With all of this, I wouldn't want to change to any other pain management medication."

10 / 10
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  • Bug...
  • January 29, 2018

For Pain "I almost died taking this. Horrible heart racing and arrhythmias. Pain management gave me this after 2 very bad days after quad back injections. I took only twice. Husband had to take me to the ER at 5 in the morning due to side effects of this medication. They changed to 10 mg hydro qty 20, which helped with pain and lost sleep. I reported this to the manufacturer of this medication, and they were very understanding and seemed concerned. Never again will I take these medications due to DRs getting kickbacks from the manufacturer. Be aware first time using, and if things don't seem right, stop taking. It's garbage, IMO."

1 / 10
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  • And...
  • Taken for 5 to 10 years
  • May 7, 2016

For Pain "I have three herniated discs in my lower back. I started taking Nucynta after I built up a tolerance to other painkillers (codeine, hydrocodone, oxycodone). If I take a whole pill, it puts me to sleep, the pain goes away, but my face and neck itch; this can last 6 hours. I have found if I take half a pill, it takes the edge off the pain, and there's no itching, and I don't feel sleepy; I can work and even drive. I take these halves every 5 hours until I know the pain subsides. I'm on and off these pills; never had other side effects. I don't take them long enough (maybe 2-4 days) to get addicted."

8 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.