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User Reviews for Nucynta to treat Pain

The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.

Nucynta Rating Summary

User Ratings
19% (46)
14% (34)
17% (41)
8% (19)
4% (9)
6% (15)
3% (7)
6% (14)
2% (6)
21% (51)
6.2/10 Average Rating
242 ratings from 259 user reviews

Compare all 1456 medications used in the treatment of Pain.

Reviews for Nucynta

Anonymous · Taken for less than 1 month July 12, 2020

“Medicine made me feel very loopy and unable to concentrate. Could not wait until it was out of my system. Made me tired for days.”

2 / 10
Laura Anderson February 13, 2020

“I've never had more side effects with any other medication. I ended up in the ER, I'll get into that more later. -Blurry vision, can't read off my phone. Can't focus eyes, they feel strained. Causes this 'psychedelic effect' where things look like it's moving with slight colors. -Chest pain. Went to ER. Gave medication to slow heart which was 150 bpm -Heart pounding, tightness in chest, fast heart rate, low blood pressure. -unable to concentrate/poor memory. Forgetting mid sentence. -Dizzy, room is spinning. Uncoordinated. -Depressed breathing -Hallucinations. Thought I saw a red bug on me but it was just my birthmark, I was hallucinating! NEVER hallucinated before. -Restlessness -Skin on hands and feet turned blue -Anxiety/depression. I have slight anxiety but not like this. Made me depressed. -Urinary pain (from coating on these pills made to prevent people from misusing) -Heaviness in limbs -Trouble swallowing -severe constipation -Indigestion -Low energy”

1 / 10
Cel · Taken for 2 to 5 years February 6, 2020

“I have been on Nucynta for over 3 years now. I suffer from scoliosis, fibromyalgia and RA. I’ve been on 100 mg 4x/day then went to 3x/day recently. Something interesting about this drug is the way it’s processed in the body. Some people lack particular gene functions that break down most pain medications. Nucynta is one of the only narcotics that bypasses this gene process, therefore people who lack the cyp-2d6 (gene) “regulator”, can get more adequate pain relief. But people not lacking this genetic predisposition often have not so good of an experience. OVERALL, for some people Nucynta (tapentadol) can be a life saver when nothing else works and I say all this for those who may want to research into why certain drugs don’t work as well for them. The only downside for me was, even though I have good insurance, it was originally over $1,200 For 90- 100mg pills. Hope this helps someone!”

10 / 10
jan January 9, 2020

“I have been unable to get this medicine so far”

1 / 10
Shano December 18, 2019

“I broke both of my feet falling off my roof in winter after fixing my satellite I than got compartment syndrome in left foot and had to have. An emergency fasciatomy for those that don't know what that is they basically had to cut my foot wide open in 3 places to relieve the pressure and cuts had to stay wide open so for about 3 months I was in horrible pain they prescribed oxycontin 60mg 2x a day and 30mg 3x a day and for pain it did absolutely nothing but in 3 months I was addicted I went to pain management dr complained he gave me nuycenta and life was such much better went from being in excruciating pain to barely any pain at all not to mention wasn't high off pills either so could actually function.. Nuycenta was a gods send when I needed it most, the only bad thing is most insurances didn't pay for it when I was on it that was in 2015 so this might b different now but I had to pay 400 a month for 60 50 mg pills”

10 / 10
Bimmerland · Taken for less than 1 month December 15, 2019

“Started nucynta 100mg every 12 hours with percocet 10/325 in between for my pain. Nucynta does nothing for pain. All it does is add another level of opioid addiction. Very expensive and does not reduce my pain level. Back to spine clinic to get lower dosage so I can cleanly get off of it. Had the same experience with levorphanol.”

1 / 10
Kinks · Taken for 5 to 10 years November 21, 2019

“I have been on Nucynta for over 6 years. I am a post cancer patient. I suffer from nerve damage from chemotherapy, fibromyalgia. Degenerative disc disease in my lower back. Dysplasia and arthritis in my left hip after 5 surgeries and bad scarring. I have had injections and tried every opioid under the sun. Until my rheumatologist started me on Nucynta life became different. I still have pain as with ANY of them . But I got my life back. There is no generic and it is expensive but taken properly it works. It may night work for everyone. But to me roxy's and oxycodone and all that are trash. The other part is I can't have anything with acetaminophen due to having cancer in my liver .so I'm very limited. I think it's worth a try. Methadone ugh no way. People never get off that. Try nucynta! Good luck! Best!”

10 / 10
Jp November 7, 2019

“I have ankylosis spondylitis since I was drafted and resulted in a 4F deferment. That was 1970. This med has been a game changer for me. I wake up not as stiff as I have been without the drug. To help with the bowel motion I drink smooth moves tea and it works. If not for My Dr. I would be homeless being unable to work. Good luck to all who suffer day by day”

9 / 10
Spanky · Taken for 6 months to 1 year November 5, 2019

“I gave this medication a rating of one because zero wasn’t an option. Very expensive and relieved no pain in my case. I hope others do better. I was bitterly deceived with this medication.”

1 / 10
Clayton · Taken for 1 to 6 months October 18, 2019

“Have been taking for about 6 weeks now and it has been effective for pain relief with only minor side effects. The only problem is the expense. With insurance it is $200.00 for a 30 day supply of 4 per day.”

10 / 10
Gerry October 17, 2019

“I have been on Nucynta 200 ERmg 3 X Day and Tramadol 50mg 3 X Day for two years now. I was on all the other pain meds from Percocet to fentanyl and Nucynta has been great for me. I have degenerative disc disease I broke my back at L4 and L5 and I have rods and screws I have a chronic case of kidney stone and kidney damage. If you have chronic pain and nothing is helping try Nucynta hopefully it might help you as it has helped me. One note, no pain medication will relieve your pain 100% but as for me my pain is 70% to 85% controlled (depending on the weather) but I have learned to live and manage my remaining pain. Apart from the medication I use ice and heat to also help with the pain. Good luck finding your pain relief because no one should live their life in chronic pain and also good luck in finding a good pain management doctor that believes you. God Bless”

9 / 10
Ritz September 24, 2019

“I don't want to give this medication a high rating. My husband was put on this medication last week at first he thought it was great that then trouble came he had problems focusing, he broke out with a rash, had constipation could not eat and always felt like he was going to throw up. When I saw the rash on his leg I immediately call the pharmacist and a pharmacist told him to stop taking this medication and on top of that he is on antidepressants and blood thinners. ”

1 / 10
Rose · Taken for 2 to 5 years August 24, 2019

“I have about 8 separate diagnoses in my spine including severe degenerative disc disease and arthritis. I am in horrific pain all the time. I had been taking Vicodin 10 multiple times through the day and only got a short time of relief. I went to a new pain management doc and he gave me Nucynta. I haven't had anything work so well! I take 100mg 3 times a day and I have zero pain. I feel like a whole new person! I'm not counting the hours til I can take another pill. My co pay is 50 dollars with good insurance but for me its well , well worth it. Definitely worth giving this medicine a try.”

10 / 10
Ace · Taken for 1 to 6 months August 16, 2019

“I take Nucynta in conjunction with Norco for neuralgia caused by a severe case of shingles (post herpetic nerve pain). While my pain management doctor is trying blocks on the nerves, they have yet to be successful. The combination on Nucynta and Norco are giving me the temporary relief to get me through until I can find success from a longer term solution.”

7 / 10
Kgb856 · Taken for less than 1 month July 30, 2019

“Prescribed for neuropathic pain and psoriasis arthritis, although I also have phantom pain related to an accident and subsequent amputation. It has only been week, but it seems there's no helping everything but the phantom pain, I'm not really sure that anything is going to take that away. When that comes it is extremely sudden and it also passes just as suddenly. On the whole I'd give it an 8/10. BTW, I'm on 200 mg a day.”

8 / 10
MajorDee July 29, 2019

“I said I would come back and share. Nucynta has literally given me my life back. I have significant chronic pain issues. I was on oxycodone for a while but felt it was no longer working. Tried a few others until this one and I have felt like my pain has been relieved significantly and I am so thankful! Even my husband noticed the difference he said it was literally like night and day. So much to the point where this medication is 4 times more expensive then the others but he said with those results its worth it.”

10 / 10
MajorDee June 24, 2019

“I am on a trial of Nucynta medication 50mg every 6 hours. I have been on several different pain medications and lately they have not been working due to a worsening condition. I have fibromyalgia, DDD (degenerative disc disease) and arthritis in my cervical and lumbar spine as well as a tumor that caused me to have a near total mandibulectomy which is now the main source of my pain. The first few days I felt very dizzy but surprisingly my pain level is so much better I cannot believe it! I hope this continues. The only downside is the cost. My co-pay was $53 dollars and that was for 7 days worth! If this works then I have to pay another $53 dollars!! So this works for me but the cost does not so I am not sure how this will all work out.”

8 / 10
MajorD · Taken for less than 1 month June 20, 2019

“I cannot rate this yet because I just started yesterday, 50mg every six hours. I am trying this for 7 days to evaluate the effectiveness for my chronic and acute pain. I have a almost complete mandibulectomy due to a tumor, fibromyalgia, and herniated disc and arthritis in my back. I was upset that my copay was $53 dollars for a 7 day supply! So far I have taken 3 doses. I have been extremely dizzy, and felt a little "foggy". I also started experiencing loose stools after the 2nd dose. This is my second day and I hope things get better. I will also provide an update.”

Pat1sg · Taken for 2 to 5 years June 17, 2019

“I take one to two 50 mg a day in conjunction with Tramodol. Tramodol during the day and the Nucynta in the evening. The Nucynta really knocks out my joint and back pain with few side effects. Yes, it does cost a bit as there is no generic, but this has been a real help. Until I was put on this regimen I was taking way to many Ibuprofen all day long.”

9 / 10
Mommab · Taken for less than 1 month June 10, 2019

“My doctor put me on Nucynta 50 mg 2x day for pain. I still have the back pain and no relief, it did however, make me sleep for 30+ hours, make me sick to my stomach, gave me diarrhea and did not help. I took this Saturday night at 11:00 pm. It is now Monday morning 11:30 am, and I just want to sleep. I have no appetite. I haven’t eaten anything since 5:00 pm Saturday and I’m still not hungry. This medicine is the WORST.”

1 / 10
Peaches · Taken for less than 1 month May 31, 2019

“Nucynta is the worst! I've suffered from chronic pain for years & have tried many different pain meds. Long-acting, short-acting, brand, generic, tabs, caps, patch, etc, but nothing I've tried has EVER made me feel as lousy as Nucynta! Nausea, fatigue, dizziness, headache, & achy. It didn't suppress my pain the way I had expected it to considering it cost $1071.69 for 120 tabs! Thank goodness my ded was met so it cost me $0, but I'm feeling some kinda way about my ins paying this much $ for something so useless & ineffective!! I feel a refund is in order! I'd much rather go back to my Percocet 10mg × 4/day which was WAY more effective & less expensive! If you're prescribed this drug & are unable to tolerate it, be sure to have a standby available! Plus, this drug is NOT readily available at any pharmacy & has to be ordered. A p/a from the insurance is required & there is NO generic equivalent. Kudos to those Nucynta IR provides even minimal relief, and CONGRATS to those it actually works well for!”

2 / 10
kittycat5 · Taken for less than 1 month March 10, 2019

“I was given this medication 2 weeks ago, 50 mg 3 times a day. On week 1, I felt a significant relief from pain, but in the second week, 7 days later, I became stomach sick, vomiting and diarrhea, nauseous, and my back pain (3 fractured lumbar), came back with a vengeance, feeling the worst pain ever, and I'm still taking the prescribed dose. Whats up with that??? I'm so disappointed because I thought, after 8 years of suffering from chronic pain day after day, that I finally found something to address this pain. But no, it lasted all of 3-4 days and now I'm feeling more pain and less relief from the same drug...back again to see the doctor.”

3 / 10
Starr317 · Taken for 5 to 10 years February 28, 2019

“I was in a MVA in 05 that left me permanently disabled with a spinal cord injury. My spinal cord was less than 2cm of being severed. Nothing helped the pain, not Fentanyl or even Morphine as my doctor suggested Methadone as a last resort, I was 37 yo and said no, not at my age. A PA offered Nucynta as she had just read an article and on this day, I got my life back! This wasn't just a game changer, it was a miracle drug, as it worked miracles for me. How does one thank the makers of this one med that did so much to help me and my family?”

10 / 10
EDS199 · Taken for 2 to 5 years February 10, 2019

“I am a young uni student that has been experiencing severe chronic pain for 5 years. 2 years ago my doc prescribed nucynta and it was a game changer. Before I was taking 4 different types of meds for my EDS and spinal stenosis but with no affect. Nucynta has allowed me to live with a tolerable amount of pain all while performing in university.”

10 / 10
Vickyo · Taken for less than 1 month February 3, 2019

“I was given this drug to replace Tramadol for my CRPS (Chonic regional pain syndrome). I also take Norco 10mg 5 x a day. The Nycynta was scary. I was told by the doctor to watch for serotonin syndrome because I take Cymbalta. When I picked up the prescription the pharmacist was very concerned and went through all of the possible side effects. I took an extended release 50mg dose with no problems and then 12 hours later I took the second dose. About 6 hours later my heart started racing and did not stop for 12 hours. I called the doctor and he said do not take another dose. I went to bed with my heart rate still elevated and woke up completely drenched in sweat. It was the scariest side effects I have ever had with a drug. To this day I still wake up with sweats although not nearly as bad as when I first took this drug. I think it this drug has caused me to have some long term effects. It was awful and very dangerous. I should have been hospitalized. Beware if you are prescribed this medication. It did not help with the pain.”

1 / 10