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User Reviews for Nucynta to treat Pain

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Nucynta Rating Summary

User Ratings
6.3/10 Average Rating
286 Ratings with 248 User Reviews

What next? Compare all 1671 medications used in the treatment of Pain.

Reviews for Nucynta

Rose · Taken for 2 to 5 years August 24, 2019

"I have about 8 separate diagnoses in my spine including severe degenerative disc disease and arthritis. I am in horrific pain all the time. I had been taking Vicodin 10 multiple times through the day and only got a short time of relief. I went to a new pain management doc and he gave me Nucynta. I haven't had anything work so well! I take 100mg 3 times a day and I have zero pain. I feel like a whole new person! I'm not counting the hours til I can take another pill. My co pay is 50 dollars with good insurance but for me its well , well worth it. Definitely worth giving this medicine a try."

Ace · Taken for 1 to 6 months August 16, 2019

"I take Nucynta in conjunction with Norco for neuralgia caused by a severe case of shingles (post herpetic nerve pain). While my pain management doctor is trying blocks on the nerves, they have yet to be successful. The combination on Nucynta and Norco are giving me the temporary relief to get me through until I can find success from a longer term solution."

Kgb856 · Taken for less than 1 month July 30, 2019

"Prescribed for neuropathic pain and psoriasis arthritis, although I also have phantom pain related to an accident and subsequent amputation. It has only been week, but it seems there's no helping everything but the phantom pain, I'm not really sure that anything is going to take that away. When that comes it is extremely sudden and it also passes just as suddenly. On the whole I'd give it an 8/10. BTW, I'm on 200 mg a day."

MajorDee July 29, 2019

"I said I would come back and share. Nucynta has literally given me my life back. I have significant chronic pain issues. I was on oxycodone for a while but felt it was no longer working. Tried a few others until this one and I have felt like my pain has been relieved significantly and I am so thankful! Even my husband noticed the difference he said it was literally like night and day. So much to the point where this medication is 4 times more expensive then the others but he said with those results its worth it."

MajorDee June 24, 2019

"I am on a trial of Nucynta medication 50mg every 6 hours. I have been on several different pain medications and lately they have not been working due to a worsening condition. I have fibromyalgia, DDD (degenerative disc disease) and arthritis in my cervical and lumbar spine as well as a tumor that caused me to have a near total mandibulectomy which is now the main source of my pain. The first few days I felt very dizzy but surprisingly my pain level is so much better I cannot believe it! I hope this continues. The only downside is the cost. My co-pay was $53 dollars and that was for 7 days worth! If this works then I have to pay another $53 dollars!! So this works for me but the cost does not so I am not sure how this will all work out."

MajorD · Taken for less than 1 month June 20, 2019

"I cannot rate this yet because I just started yesterday, 50mg every six hours. I am trying this for 7 days to evaluate the effectiveness for my chronic and acute pain. I have a almost complete mandibulectomy due to a tumor, fibromyalgia, and herniated disc and arthritis in my back. I was upset that my copay was $53 dollars for a 7 day supply! So far I have taken 3 doses. I have been extremely dizzy, and felt a little "foggy". I also started experiencing loose stools after the 2nd dose. This is my second day and I hope things get better. I will also provide an update."

Pat1sg · Taken for 2 to 5 years June 17, 2019

"I take one to two 50 mg a day in conjunction with Tramodol. Tramodol during the day and the Nucynta in the evening. The Nucynta really knocks out my joint and back pain with few side effects. Yes, it does cost a bit as there is no generic, but this has been a real help. Until I was put on this regimen I was taking way to many Ibuprofen all day long."

Mommab · Taken for less than 1 month June 10, 2019

"My doctor put me on Nucynta 50 mg 2x day for pain. I still have the back pain and no relief, it did however, make me sleep for 30+ hours, make me sick to my stomach, gave me diarrhea and did not help. I took this Saturday night at 11:00 pm. It is now Monday morning 11:30 am, and I just want to sleep. I have no appetite. I haven’t eaten anything since 5:00 pm Saturday and I’m still not hungry. This medicine is the WORST."

Peaches · Taken for less than 1 month May 31, 2019

"Nucynta is the worst! I've suffered from chronic pain for years & have tried many different pain meds. Long-acting, short-acting, brand, generic, tabs, caps, patch, etc, but nothing I've tried has EVER made me feel as lousy as Nucynta! Nausea, fatigue, dizziness, headache, & achy. It didn't suppress my pain the way I had expected it to considering it cost $1071.69 for 120 tabs! Thank goodness my ded was met so it cost me $0, but I'm feeling some kinda way about my ins paying this much $ for something so useless & ineffective!! I feel a refund is in order! I'd much rather go back to my Percocet 10mg × 4/day which was WAY more effective & less expensive! If you're prescribed this drug & are unable to tolerate it, be sure to have a standby available! Plus, this drug is NOT readily available at any pharmacy & has to be ordered. A p/a from the insurance is required & there is NO generic equivalent. Kudos to those Nucynta IR provides even minimal relief, and CONGRATS to those it actually works well for!"

kittycat5 · Taken for less than 1 month March 10, 2019

"I was given this medication 2 weeks ago, 50 mg 3 times a day. On week 1, I felt a significant relief from pain, but in the second week, 7 days later, I became stomach sick, vomiting and diarrhea, nauseous, and my back pain (3 fractured lumbar), came back with a vengeance, feeling the worst pain ever, and I'm still taking the prescribed dose. Whats up with that??? I'm so disappointed because I thought, after 8 years of suffering from chronic pain day after day, that I finally found something to address this pain. But no, it lasted all of 3-4 days and now I'm feeling more pain and less relief from the same drug...back again to see the doctor."

Starr317 · Taken for 5 to 10 years February 28, 2019

"I was in a MVA in 05 that left me permanently disabled with a spinal cord injury. My spinal cord was less than 2cm of being severed. Nothing helped the pain, not Fentanyl or even Morphine as my doctor suggested Methadone as a last resort, I was 37 yo and said no, not at my age. A PA offered Nucynta as she had just read an article and on this day, I got my life back! This wasn't just a game changer, it was a miracle drug, as it worked miracles for me. How does one thank the makers of this one med that did so much to help me and my family?"

EDS199 · Taken for 2 to 5 years February 10, 2019

"I am a young uni student that has been experiencing severe chronic pain for 5 years. 2 years ago my doc prescribed nucynta and it was a game changer. Before I was taking 4 different types of meds for my EDS and spinal stenosis but with no affect. Nucynta has allowed me to live with a tolerable amount of pain all while performing in university."

Vickyo · Taken for less than 1 month February 3, 2019

"I was given this drug to replace Tramadol for my CRPS (Chonic regional pain syndrome). I also take Norco 10mg 5 x a day. The Nycynta was scary. I was told by the doctor to watch for serotonin syndrome because I take Cymbalta. When I picked up the prescription the pharmacist was very concerned and went through all of the possible side effects. I took an extended release 50mg dose with no problems and then 12 hours later I took the second dose. About 6 hours later my heart started racing and did not stop for 12 hours. I called the doctor and he said do not take another dose. I went to bed with my heart rate still elevated and woke up completely drenched in sweat. It was the scariest side effects I have ever had with a drug. To this day I still wake up with sweats although not nearly as bad as when I first took this drug. I think it this drug has caused me to have some long term effects. It was awful and very dangerous. I should have been hospitalized. Beware if you are prescribed this medication. It did not help with the pain."

Kt December 21, 2018

"This is a narcotic......I took it one time and said no way!! I was so high I almost fell off the step stool. Slept for hours. Literally stoned... I was. That is not a way to treat pain. Sorry, it might help with the pain cuz you're asleep and don't feel it. There has to be a better way to treat pain then narcotics. People are dying everyday because of the opioids. Why are we still giving them out?"

Devon · Taken for 6 months to 1 year November 27, 2018

"Been on nucynta 100mg every 4 hours (max 5/day) with moderate effect. I have a synthetic disc in my back (injury from catching a seizing patient- I’m An RN) and an autoimmune disease that is affecting my nervous system so I have neuropathy everywhere. Nucynta helps with muscle pain as well as nerve pain. I take gabapentin 800mg four times a day along with baclofen for spasm and have had no problems. I’m also on 2 antidepressants (this disease process has also affected my mood and cognitive function) and an anxiolytic. Nucynta helps as much as any other med I’ve been on (hydrocodone, oxycodone, morphine, fentanyl)."

FLkeys · Taken for 1 to 6 months October 25, 2018

"Taking 150 mg every 8 hrs. This was to replace 15 mg morphine ER twice a day and 10 mg Oxy every 4 hrs. I get the queasy stomach and the constipation but ZERO pain relief. I think the pharma co's put this out so people think they care. Waste of time and money"

dimples · Taken for 5 to 10 years October 23, 2018

"This is the most dangerous drug on the market I was on it for ten years ninety pills a month and still needed more. I was told by doctor it was non addictive. I have written letters to the FDA and I am going to my congress man to try and get this drug pulled from the shelf. I nearly died when I came off with all the withdrawal effects. Stay well away and please write to FDA so that the drug companies stop making profit from this drug."

Steve · Taken for 1 to 2 years September 3, 2018

"On 50mg three times a day for 2 years. I took it to treat Reflex Sympathetic Dystrophy also known as Complex Regional Pain Syndrome. Tolerated well and it seemed to help a little, just enough to take the edge off the pain. After two years it stopped working so the dose was increased to 75mg 3x a day which caused the side effect of Serotonin Syndrome. I had to be hospitalized and almost died extreme acute hypertension! Almost a year later and still suffering from the incident. It ruined my life. Be extremely careful! My Doctor will not Rx it anymore for any of his patients because of the severity of adverse side effects he has witnessed in some of his patients. And if your Doctor does increase your dose or add a new drug check for interactions in case they don't know."

Luke September 1, 2018

"I wanted to take this medication to replace a stronger narcotic I was on. I have a list of problems but I was taking this for CRPS (Complex regional pain syndrome) specifically. I was very excited to try this drug, I thought I was choosing the lesser of evils by going with this. The pharmacist was very concerned when I picked it up an insisted that I get a Narcan shot for accidental overdose. I eagerly got up early the next morning to see if this stuff worked. I didn't take an other medication that day because the pharmacist scared the hell out of me. I started to feel it and was immediately disappointed by it's analgesic properties. It helped with the nerve pain a little. About a half hour went by and I started to shake uncontrollably. I got a horrible headache. My vision was so blurred I couldn't see the letters on my keyboard. I thought I would try it a couple more times thinking these side effects would improve but they just got worse. My heart started to palpitate, so I threw in the towel."

PeeWee Pony · Taken for less than 1 month July 9, 2018

"Does not help my pain at all."

Longisl631 · Taken for 1 to 6 months June 23, 2018

"All it did was make me stutter. Weak, how could they call this medicine. Does not alleviate any pain."

Mt · Taken for less than 1 month June 16, 2018

"I was taking 15mg oxycodone & 15mg OxyContin ER, my dr just switched my meds to Belbuca film & 75mcg Nucynta ER WHICH IS OUTRAGEOUS!!!! My insurance company doesn’t pay for it! $100 for 14 days of it! Neither of the meds work, they make me very tired, dizzy, headaches, The doctor said I wouldn’t have withdrawals but that’s a lie. I have zero pain relief! Complete waste of money! It has more bad side effects than good things about it!! Especially when you read on it & that’s what it first says. Please be careful."

eggman · Taken for 2 to 5 years June 16, 2018

"I've been on Nucynta ever since it first came out has been working great but now the insurance company won't pay for it supposedly because I take too many mg's of opiods a day. I've been taking two 150mg's of Nucynta ER a day and one 10mg of oxycodone a day for years they want to screw it all up...."

Kjjdorsey · Taken for 1 to 6 months February 11, 2018

"After being diagnosed with Complex regional pain syndrome (CRPS) four years ago, I have been prescribed everything from Tramadol, Butrans Patches to Percocet. It was difficult to figure out which combination of meds would work best for me. Two years ago, I had a SCS (spinal cord stimulator) implanted. It helped but it did not take the pain away. After being on Oxy and Percocet for years, I spoke with my pain management doctor to change drugs. I started on Nucynta (50 mg 4x a day) along with MS Contin and Lyrica. This combination has effectively controlled my pain. I recently decreased my dosage to 2x a day."

Bird50 February 10, 2018

"I've been on this medication for 2yrs now. I'm status-post mastectomy and reconstruction. 2013- I was taking narcotics for severe pain. This drug was recommended to me by a pain management physician. He started me off at 150mg twice daily. After 1 yr. I knew I needed to start to wean myself off these pain medications. I'm currently taking 100mg twice daily. My pain is getting less and less. I'm going to see my pain specialist next week and ask for another lower dose. Not sure if these drug comes in 75mg."