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Durolane and Headaches: What Users Say

Headaches: mentioned by 6 users (2.3%)

Based on user experiences from 262 Durolane reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

pain 44.7%
swelling 11.5%
discomfort 8.0%
severe pain 6.9%
stiffness 3.8%
nausea 2.7%
headaches 2.3%
soreness 2.3%
tingling 1.9%
itching 1.5%

Reviews for Durolane

Commonly mentioned side effects
  • Beb...
  • December 5, 2020

For Osteoarthritis "I had Durolane injection in both knees yesterday. I have a headache so bad. I feel sick to my stomach, my left knee is larger and hard from the top of my knee and down, he drained it yesterday as well. I don’t know what to I wish I didn’t get it. This is the worst feeling. If I feel the same tomorrow I will call the Dr's office again. My right knee is very sore. They feel like someone is hitting me in the knees with a hammer, not stopping? I hope it’s not a blood clot. I don't know. I can hardly walk. For me day 2 it’s terrible, thank you for letting me tell my experience"

1 / 10
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76 Report
  • jo ...
  • Taken for less than 1 month
  • February 5, 2021

For Osteoarthritis "I am a 49-year-old female suffering from severe osteoarthritis of the right knee. Have tried steroid injections with very temporary relief (less than a month). Dr. recommended Durolane. Had my injection yesterday (2/4/2021). Pain was very intense and nearly fell when I stood up to leave. Had a pounding headache by the time I got home and had a rough time getting in the house. Iced knee and took ibuprofen as recommended. Ached through the night but I was able to sleep on and off. When I woke this morning, the pain is worse than before the injection. As I walked into the kitchen, my knee gave out and I nearly fell. I am off work today and tomorrow. Praying that taking it easy and icing my knee, the pain will subside soon. I'm wishing I didn't get the injection at this point. I have pain radiating in both directions (from knee to ankle/from knee to hip). I'll keep you updated on when and if this pain lets up."

1 / 10
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32 Report
  • Lor...
  • Taken for less than 1 month
  • January 8, 2020

For Osteoarthritis "I had a Durolane injection after 2 of another brand that went well. United Healthcare insisted on this one this time. 20 minutes after the injection, I had extreme nausea and a headache to the point of not seeing well. The pain is worse now than before any shots 2 years ago. I have no idea how to make the pain stop now."

1 / 10
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18 Report

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  • Ali...
  • October 16, 2019

For Osteoarthritis "On 10/15/19, I received my first injection of Durolane. I am 66 yrs. old with osteoarthritis, bone on bone in my knee. The initial injection hurts more than a cortisone injection, but only for a minute. The gel is thicker, so it goes in slower. Initially, I could not bend my knee or walk comfortably. I definitely could not get the injection and drive. My knee was swollen and uncomfortable for a bit, but I sat on my sofa with my knee up for the day. I did have a headache later in the day, but I took Advil and it subsided. I could not use the leg to get up from a sitting position, which was cumbersome. I went to bed that evening, woke up the next morning, and 90% of the pain was gone. I would suggest this injection as of day 2. I'm hoping it lasts a few months. If it does, I would definitely do it again."

10 / 10
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18 Report
  • Dai...
  • Taken for less than 1 month
  • June 3, 2022

For Osteoarthritis "I had Durolane injections in both knees ten days ago. My side effects included nausea, headache, back pain, tingling. Now my knees ache and burn so badly every movement is excruciating. I can barely get around the house. At seventy-two years old, this is the WORST decision I’ve ever made. PLEASE, if you are thinking about getting Durolane injections, don’t. Once it’s done, there’s no going back."

1 / 10
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11 Report
  • Cca...
  • Taken for less than 1 month
  • September 12, 2021

For Osteoarthritis "Got my injection July 29th, 2021... I've always been able to walk off the pain of my injections. Not this one, right away the pain kicked in super bad at night. I waited a few days, every night the same throbbing, itching, and tingling. Not to mention the sore I got on my injection spot. I don't recommend this shot to anyone. I've had so many side effects and my knees are more painful than before I came. Muscle weakness, dizziness, weight loss, migraines, and numbness in legs and feet. Poor blood circulation... stay away from this shot... just say NO."

1 / 10
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3 Report

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